CAS 5378-62-1

2-chloro-5-(hydrazinylcarbonyl)benzenesulfonamide

Description:

2-Chloro-5-(hydrazinylcarbonyl)benzenesulfonamide, with the CAS number 5378-62-1, is a chemical compound characterized by its sulfonamide functional group, which is known for its antibacterial properties. This compound features a chloro substituent at the 2-position and a hydrazinylcarbonyl group at the 5-position of a benzene ring, contributing to its unique reactivity and potential biological activity. The presence of the sulfonamide group suggests that it may exhibit properties similar to other sulfonamide antibiotics, although its specific pharmacological effects would depend on its structure and interactions within biological systems. The hydrazine moiety can also indicate potential applications in medicinal chemistry, particularly in the development of antitumor agents. In terms of physical properties, compounds of this nature may exhibit moderate solubility in polar solvents and may be sensitive to light and moisture. Overall, 2-chloro-5-(hydrazinylcarbonyl)benzenesulfonamide represents a compound of interest in both synthetic and medicinal chemistry contexts.

Formula: C₇H₈ClN₃O₃S

InChI: InChI=1/C7H8ClN3O3S/c8-5-2-1-4(7(12)11-9)3-6(5)15(10,13)14/h1-3H,9H2,(H,11,12)(H2,10,13,14)

SMILES: c1cc(c(cc1C(=NN)O)S(=O)(=O)N)Cl

Synonyms:

• 2-Chloro-5-(Hydrazinocarbonyl)Benzenesulfonamide

2-Chloro-5-(hydrazinecarbonyl)benzenesulfonamide

CAS: 5378-62-1

Formula: C₇H₈ClN₃O₃S

Color and Shape: Solid

Molecular weight: 249.6747

Ref: IN-DA00DQFV

2-Chloro-5-(hydrazinocarbonyl)benzenesulfonamide

Controlled Product

CAS: 5378-62-1

Applications 2-Chloro-5-(hydrazinocarbonyl)benzenesulfonamide is an intermediate in the synthesis of Besulpamide (B319750) which is an antihypertensive agent. It also exhibits diuretic activity in rats and dogs.
References Bojarska, J., et al.: J. Mol. Struct. 1116, 22 (2016); Colombo, M., et al.: Methods Find Exp Clin Pharmacol. 9, 101 (1987); Esteve, J., et al.: Methods Find Exp Clin Pharmacol.9, 121 (1987)

Formula: C₇H₈ClN₃O₃S

Color and Shape: Neat

Molecular weight: 249.67

Ref: TR-C370000

2-Chloro-5-(hydrazinecarbonyl)benzene-1-sulfonamide

CAS: 5378-62-1

2-Chloro-5-(hydrazidecarbonyl)benzene-1-sulfonamide is an aliphatic aldehyde that is used to synthesize other chemicals. It can be synthesized from the condensation of 2-chloroacetaldehyde with hydrazine and formaldehyde in the presence of a base. This compound has been shown to have diuretic and saluretic properties, which are due to its ability to increase urine flow by inhibiting reabsorption of sodium ions in the kidney tubules. 2-Chloro-5-(hydrazidecarbonyl)benzene-1-sulfonamide is soluble in alcohols and dioxane, but insoluble in water. This compound hydrolyzes in acidic conditions, so it cannot be stored for long periods without protection from moisture.

Formula: C₇H₈ClN₃O₃S

Purity: Min. 95%

Molecular weight: 249.68 g/mol

Ref: 3D-FAA37862