CAS 538-75-0

Dicyclohexylcarbodiimide

Description:

Dicyclohexylcarbodiimide (DCC) is an organic compound widely used as a coupling agent in peptide synthesis and other organic reactions. It is characterized by its unique structure, featuring two cyclohexyl groups attached to a central carbodiimide functional group. DCC is typically a white to off-white crystalline solid at room temperature and is known for its relatively low solubility in water but good solubility in organic solvents such as dichloromethane and dimethylformamide. One of its key characteristics is its ability to activate carboxylic acids, facilitating the formation of amide bonds, which is crucial in peptide synthesis. DCC is also known for its stability under standard laboratory conditions, although it can decompose upon prolonged exposure to moisture or acidic conditions. Safety precautions are necessary when handling DCC, as it can be a skin and respiratory irritant. Overall, DCC is a valuable reagent in organic chemistry, particularly in the synthesis of complex molecules.

Formula: C₁₃H₂₂N₂

InChI: InChI=1S/C13H22N2/c1-3-7-12(8-4-1)14-11-15-13-9-5-2-6-10-13/h12-13H,1-10H2

InChI key: InChIKey=QOSSAOTZNIDXMA-UHFFFAOYSA-N

SMILES: N(=C=NC1CCCCC1)C2CCCCC2

Synonyms:

• 1,3-Dicyclohexylcarbodiimide
• Bis(cyclohexyl)carbodiimide
• Carbodiimide, N,N-Dicyclohexyl-
• Carbodiimide, dicyclohexyl-
• Cyclohexanamine, N,N'-methanetetraylbis-
• DCC
• Dccd
• Dcci
• Diciclohexilcarbodiimida
• Dicyclohexyl CARBODIMIDE
• Dicyclohexylcarbodiimid
• Dicyclohexylcarbodiimide
• N,N'-Dicyclohexyl carbodiimide
• N,N'-Dicyclohexylcarbodimide
• N,N'-Methanetetraylbis[cyclohexanamine]
• N,N'-Methanetetraylbiscyclohexanamine
• N,N'-dicyclohexyl carbodimide
• N,N'-diphenylcarbodiimide
• Nsc 30022
• Nsc 53373
• Nsc 57182

N,N'-Dicyclohexylcarbodiimide (25% in Pyridine, ca. 1.2mol/L)

CAS: 538-75-0

Formula: C₁₃H₂₂N₂

Color and Shape: Colorless to Light yellow clear liquid

Molecular weight: 206.33

Ref: 3B-D0437

N,N'-Dicyclohexylcarbodiimide

CAS: 538-75-0

Formula: C₁₃H₂₂N₂

Purity: >98.0%(GC)

Color and Shape: White or Colorless to Light yellow powder to lump to clear liquid

Molecular weight: 206.33

Ref: 3B-D0436

N,N'-Dicyclohexylcarbodiimide, 99%

CAS: 538-75-0

N,N'-Dicyclohexylcarbodiimide is a carboxyl activating reagent used in peptide synthesis. It acts as a dehydrating agent for the preparation of amides, ketones and nitriles. It is involved in the preparation of esters by reacting tertiary alcohols with carboxylic acid. It is utilized for the stereo

Formula: C₁₃H₂₂N₂

Purity: 99%

Color and Shape: White to pale yellow, Crystalline mass or fused or waxy solid

Molecular weight: 206.33

Ref: 02-A10973

N,N’-Dicyclohexylcarbodiimide

CAS: 538-75-0

Formula: C₁₃H₂₂N₂

Purity: 98.0%

Color and Shape: Solid, Low Melting Solid

Molecular weight: 206.333

Ref: 10-F128900

N,N-Dicyclohexylcarbodiimide

CAS: 538-75-0

Formula: C₁₃H₂₂N₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 206.3272

Ref: IN-DA0035B3

N,N'-Dicyclohexylcarbodiimide

CAS: 538-75-0

N,N'-Dicyclohexylcarbodiimide

Formula: C₁₃H₂₂N₂

Purity: 99%

Color and Shape: clear. colourless liquid/white fused solid

Molecular weight: 206.32718g/mol

Ref: 54-OR60045

N,N-Dicyclohexylcarbodiimide

CAS: 538-75-0

N,N-Dicyclohexylcarbodiimide

Purity: ≥98%

Molecular weight: 206.33g/mol

Ref: 54-BUP19915

N,N''-Dicyclohexylcarbodiimide

CAS: 538-75-0

Formula: C₁₃H₂₂N₂

Purity: ≥ 99.0%

Color and Shape: White to yellow crystalline solid or liquid

Molecular weight: 206.33

Ref: 7W-GE6064

N,N-Dicyclohexylcarbodiimide

CAS: 538-75-0

N,N-Dicyclohexylcarbodiimide (Dicyclohexylcarbodiimide) is a cross-linking agent used in the synthesis of active ester-containing reagents.

Formula: C₁₃H₂₂N₂

Purity: 98.28% - 99.73%

Color and Shape: Solid

Molecular weight: 206.33

Ref: TM-T19946

Bestatin Impurity 10

CAS: 538-75-0

Formula: C₁₃H₂₂N₂

Molecular weight: 206.33

Ref: 4Z-B-119013

N,N'-Dicyclohexylcarbodiimide

Controlled Product

CAS: 538-75-0

Formula: C₁₃H₂₂N₂

Color and Shape: Off-White To Light Yellow

Molecular weight: 206.33

Ref: TR-D438500

DCC

CAS: 538-75-0

DCC is a carbodiimide coupling reagent for amide and ester formation, used in peptide synthesis in presence of benzotriazole-based additives such as HOBt or HOAt to limit epimerisation. The urea by-product is highly insoluble in water and most organic solvents; therefore it can be easily removed by filtration. The insolubility of the urea makes the use of DCC unsuitable for solid-phase peptide synthesis unlike DIC, and only suitable for solution-phase couplings. Carbodiimide reagents including DCC tend to generate an N-acylurea by-product, whose formation can be controlled by forming the activated ester first and adding the amine afterwards, together with low reaction temperatures and the choice of DCM or chloroform as solvent.

Formula: C₁₃H₂₂N₂

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 206.33 g/mol

Ref: 3D-FD05508

DCCD (Redistilled for Solid-Phase Synthesis)

CAS: 538-75-0

DCCD is a chemical inhibitor of the enzyme pyruvate dehydrogenase kinase that is used to study metabolic pathways. It inhibits the activity of this enzyme by binding reversibly to its active site, thereby blocking its phosphorylation of pyruvate dehydrogenase and thus inhibiting the conversion of pyruvate into acetyl-CoA. DCCD also has been shown to have antidiabetic effects in an experimental model. This drug has been used as a reagent for polymyxin B and other chemical inhibitors in vitro experiments.

Formula: C₁₃H₂₂N₂

Purity: Min. 95%

Molecular weight: 206.33 g/mol

Ref: 3D-KDC-1023

N,N'-Dicyclohexylcarbodiimide

CAS: 538-75-0

Formula: C₁₃H₂₂N₂

Molecular weight: 206.33

Ref: ST-EA-CP-V9021

N,N-Dicyclohexyl Carbodiimide (DCC) pure, 98%

CAS: 538-75-0

Formula: C₁₃H₂₂N₂

Purity: min. 98%

Color and Shape: White to pale yellow, Semi solid

Molecular weight: 206.33

Ref: SR-79596