CAS 538-79-4

Metanicotine

Description:

Metanicotine, with the CAS number 538-79-4, is a chemical compound that is structurally related to nicotine, a well-known alkaloid found in tobacco. It is characterized by its pyridine and pyrrolidine rings, which contribute to its pharmacological properties. Metanicotine is primarily recognized for its potential effects on the central nervous system, as it acts as a nicotinic acetylcholine receptor agonist. This interaction can influence neurotransmitter release and has implications for cognitive function and addiction. The compound is typically studied in the context of neuropharmacology and may have applications in understanding nicotine dependence and withdrawal. Additionally, metanicotine's solubility and stability in various solvents make it a subject of interest in medicinal chemistry. However, due to its structural similarity to nicotine, it may also exhibit similar toxicity and side effects, necessitating careful handling and consideration in research settings. Overall, metanicotine serves as a valuable compound for exploring the mechanisms of nicotine action and its broader implications in pharmacology.

Formula: C₁₀H₁₄N₂

InChI: InChI=1S/C10H14N2/c1-11-7-3-2-5-10-6-4-8-12-9-10/h2,4-6,8-9,11H,3,7H2,1H3

InChI key: InChIKey=JUOSGGQXEBBCJB-UHFFFAOYSA-N

SMILES: C(=CCCNC)C=1C=CC=NC1

Synonyms:

• (3E)-N-methyl-4-pyridin-3-ylbut-3-en-1-amine
• TC-2403
• TC-2403-12
• N-Methyl-4-(3-pyridinyl)-3-buten-1-amine
• Metanicotine
• NSC 66331
• N-methyl-4-(pyridin-3-yl)but-3-en-1-amine
• Pyridine, 3-[4-(methylamino)-1-butenyl]-
• 3-Buten-1-amine, N-methyl-4-(3-pyridinyl)-

Metanicotine

CAS: 538-79-4

Metanicotine is a synthetic drug that binds to the acetylcholine receptor, which is found in the brain and on neurons. It also binds to the peripheral nicotinic acetylcholine receptors, which are located on muscle cells outside of the central nervous system. Metanicotine has been shown to be an agonist at both types of receptor. The effect of metanicotine on the body depends on its concentration and duration of exposure. Chronic exposure can lead to bowel disease, while short-term exposure is associated with antinociceptive effects. Metanicotine has been shown to bind more strongly than nicotine in studies using cd-1 mice, providing a possible explanation for its increased potency. In addition, metanicotine is not broken down by acetylcholinesterase as quickly as nicotine, meaning it can have prolonged effects on cholinergic function and behavior.

Formula: C₁₀H₁₄N₂

Purity: Min. 95%

Molecular weight: 162.23 g/mol

Ref: 3D-AAA53879

Metanicotine

CAS: 538-79-4

Metanicotine is a selective nicotinic agonist with antinociceptive properties.

Formula: C₁₀H₁₄N₂

Color and Shape: Solid

Molecular weight: 162.23

Ref: TM-T69134