CAS 5381-24-8

Benzo[b]thiophene-3-methanol

Description:

Benzo[b]thiophene-3-methanol, with the CAS number 5381-24-8, is an organic compound characterized by its fused ring structure that combines a benzene ring with a thiophene moiety. This compound features a hydroxymethyl group (-CH2OH) at the 3-position of the benzo[b]thiophene framework, which contributes to its chemical reactivity and potential applications. Benzo[b]thiophenes are known for their aromatic properties, which can influence their stability and interactions with other chemical species. The presence of the hydroxymethyl group can enhance solubility in polar solvents and may also participate in hydrogen bonding, affecting the compound's physical properties. This substance may exhibit biological activity, making it of interest in medicinal chemistry and materials science. Its unique structure allows for various synthetic modifications, which can lead to derivatives with tailored properties for specific applications. Overall, benzo[b]thiophene-3-methanol represents a versatile compound within the realm of organic chemistry.

Formula: C₉H₈OS

InChI: InChI=1S/C9H8OS/c10-5-7-6-11-9-4-2-1-3-8(7)9/h1-4,6,10H,5H2

InChI key: InChIKey=UYGMKSKKGSUAHB-UHFFFAOYSA-N

SMILES: C(O)C=1C=2C(SC1)=CC=CC2

Synonyms:

• (1-Benzothiophen-3-yl)methanol
• 1-Benzothiophen-3-ylmethanol
• 3-(Hydroxymethyl)benzothiophene
• 3-Benzothiophenemethanol
• 3-Hydroxymetnylbenzo[B]Thiophene
• Benzo[B]Thiophene-3-Methanol
• [Benzo[b]thien-3-yl]methanol

3-Hydroxymetnylbenzo[b]thiophene

CAS: 5381-24-8

Formula: C₉H₈OS

Purity: 96%

Color and Shape: Solid

Molecular weight: 164.2242

Ref: IN-DA00D881

3-(Hydroxymethyl)benzo[b]thiophene

CAS: 5381-24-8

3-(Hydroxymethyl)benzo[b]thiophene

Molecular weight: 164.22g/mol

Ref: 54-OR23176

1-Benzothiophen-3-ylmethanol

CAS: 5381-24-8

Purity: 96%

Molecular weight: 164.2200012

Ref: 10-F718792

3-(Hydroxymethyl)benzo[b]thiophene

CAS: 5381-24-8

3-(Hydroxymethyl)benzo[b]thiophene is a potential anticancer agent that inhibits the PI3K/Akt pathway. It has been shown to have cytotoxic effects on colorectal adenocarcinoma cells, as well as other cancer cells. 3-(Hydroxymethyl)benzo[b]thiophene also binds to DNA and alters the structure of the double helix, leading to inhibition of DNA synthesis, which may lead to cell death. The compound has been tested in vitro and found to be effective against leukemia and colon cancer cells. It has also shown anticancer activity in vivo in mice, with no observable side effects or toxicity.

Formula: C₉H₈OS

Purity: Min. 95%

Molecular weight: 164.22 g/mol

Ref: 3D-FAA38124