CAS 53823-08-8

Cascaroside A

Description:

Cascaroside A is a natural compound primarily derived from the bark of the cascara sagrada tree (Rhamnus purshiana), known for its use in traditional medicine as a laxative. It belongs to the class of compounds known as glycosides, specifically a type of anthraquinone glycoside. Cascaroside A exhibits a yellowish-brown color and is characterized by its bitter taste. Its chemical structure includes a sugar moiety linked to an anthraquinone backbone, which contributes to its biological activity. The compound is soluble in water and alcohol, making it suitable for extraction in various formulations. Cascaroside A is known for its laxative properties, primarily due to its ability to stimulate intestinal motility. Additionally, it may possess antioxidant and anti-inflammatory effects, although further research is needed to fully understand its pharmacological profile. As with many herbal compounds, the use of cascaroside A should be approached with caution, as excessive consumption can lead to adverse effects, including abdominal cramping and diarrhea.

Formula: C₂₇H₃₂O₁₄

InChI: InChI=1/C27H32O14/c28-6-9-4-11-16(26-24(37)22(35)19(32)14(7-29)39-26)10-2-1-3-13(18(10)21(34)17(11)12(31)5-9)40-27-25(38)23(36)20(33)15(8-30)41-27/h1-5,14-16,19-20,22-33,35-38H,6-8H2/t14-,15-,16+,19-,20-,22+,23+,24-,25-,26+,27-/m1/s1

InChI key: InChIKey=MNAYRSRTNMVAPR-ZHVWOXMGSA-N

SMILES: O[C@H]1[C@]([C@]2(C=3C(=C(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)C=CC3)C(=O)C=5C2=CC(CO)=CC5O)[H])(O[C@H](CO)[C@@H](O)[C@@H]1O)[H]

Synonyms:

• 9(10H)-Anthracenone, 10-β-D-glucopyranosyl-8-(β-D-glucopyranosyloxy)-1-hydroxy-3-(hydroxymethyl)-, (10S)-
• Cascaroside A
• (10S)-10-β-D-Glucopyranosyl-8-(β-D-glucopyranosyloxy)-1-hydroxy-3-(hydroxymethyl)-9(10H)-anthracenone
• 9(10H)-Anthracenone, 10-β-D-glucopyranosyl-8-(β-D-glucopyranosyloxy)-1-hydroxy-3-(hydroxymethyl)-, (S)-
• 10-β-D-Glucopyranosyl-8-(β-D-glucopyranosyloxy)-1-hydroxy-3-(hydroxymethyl)anthracen-9(10H)-one
• CASCAROSIDEA
• 10-β-D-Glucopyranosyl-8-(β-D-glucopyranosyloxy)-1-hydroxy-3-(hydroxymethyl)-9(10H)-anthracenone
• Aloin 8-O-β-D-glucopyranoside

Cascaroside A

CAS: 53823-08-8

Formula: C₂₇H₃₂O₁₄

Molecular weight: 580.54

Ref: 4Z-C-378001

Cascaroside a

CAS: 53823-08-8

Natural glycoside

Formula: C₂₇H₃₂O₁₄

Purity: ≥ 95.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 580.53

Ref: 5G-83564

Cascaroside A

CAS: 53823-08-8

Cascaroside A is a natural anthraquinone glycoside, which is extracted primarily from the bark of Rhamnus purshiana, commonly known as cascara sagrada. This glycoside functions by stimulating peristalsis in the colon, primarily through an interaction with nerve cells in the colon wall. The enzymatic hydrolysis of Cascaroside A in the digestive tract releases anthraquinones, which act as irritants to the intestinal mucosa. This irritation prompts increased peristaltic action and moisture retention in the bowel.

Formula: C₂₇H₃₂O₁₄

Purity: Min. 95%

Molecular weight: 580.5 g/mol

Ref: 3D-DCA82308

Cascaroside A

CAS: 53823-08-8

Formula: C₂₇H₃₂O₁₄

Molecular weight: 580.54

Ref: ST-EA-CP-C259001