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CAS 53847-30-6

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2-Arachidonylglycerol

Description:
2-Arachidonylglycerol (2-AG) is a naturally occurring endocannabinoid that plays a crucial role in the endocannabinoid system, which is involved in various physiological processes. It is a glycerolipid derived from arachidonic acid and is characterized by its structure, which includes a glycerol backbone esterified with arachidonic acid at the second carbon position. 2-AG is known for its ability to bind to cannabinoid receptors, particularly CB1 and CB2, influencing neurotransmitter release and modulating pain, appetite, and immune responses. This compound is lipid-soluble and typically found in the brain and other tissues, where it acts as a signaling molecule. Its synthesis occurs through the action of diacylglycerol lipase, while its degradation is mediated by monoacylglycerol lipase. Due to its involvement in various biological processes, 2-AG has garnered interest in research related to neuroprotection, inflammation, and potential therapeutic applications in conditions such as pain and anxiety disorders.
Formula:C23H38O4
InChI:InChI=1/C23H38O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-23(26)27-22(20-24)21-25/h6-7,9-10,12-13,15-16,22,24-25H,2-5,8,11,14,17-21H2,1H3/b7-6-,10-9-,13-12-,16-15-
InChI key:InChIKey=RCRCTBLIHCHWDZ-DOFZRALJSA-N
SMILES:O(C(CO)CO)C(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O
Synonyms:
  • 1,3-Dihydroxypropan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate
  • 2-Arachidonylglycerol
  • 2-Monoarachidonoylglycerol
  • 5,8,11,14-Eicosatetraenoic acid, 2-hydroxy-1-(hydroxymethyl)ethyl ester, (5Z,8Z,11Z,14Z)-
  • 5,8,11,14-Eicosatetraenoic acid, 2-hydroxy-1-(hydroxymethyl)ethyl ester, (all-Z)-
  • 2-AG
  • 2-Arachidonyl glycerol solution in acetonitrile
  • 2-ARACHIDONOYLGLYCEROL
  • 2-Arachidonylglycerol (acetonitrile solution)
  • 5Z,8Z,11Z,14Z-EICOSATETRAENOIC ACID, 2-GLYCERYL ESTER
  • See more synonyms
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