CAS 53847-30-6

2-Arachidonylglycerol

Description:

2-Arachidonylglycerol (2-AG) is a naturally occurring endocannabinoid that plays a crucial role in the endocannabinoid system, which is involved in various physiological processes. It is a glycerolipid derived from arachidonic acid and is characterized by its structure, which includes a glycerol backbone esterified with arachidonic acid at the second carbon position. 2-AG is known for its ability to bind to cannabinoid receptors, particularly CB1 and CB2, influencing neurotransmitter release and modulating pain, appetite, and immune responses. This compound is lipid-soluble and typically found in the brain and other tissues, where it acts as a signaling molecule. Its synthesis occurs through the action of diacylglycerol lipase, while its degradation is mediated by monoacylglycerol lipase. Due to its involvement in various biological processes, 2-AG has garnered interest in research related to neuroprotection, inflammation, and potential therapeutic applications in conditions such as pain and anxiety disorders.

Formula: C₂₃H₃₈O₄

InChI: InChI=1/C23H38O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-23(26)27-22(20-24)21-25/h6-7,9-10,12-13,15-16,22,24-25H,2-5,8,11,14,17-21H2,1H3/b7-6-,10-9-,13-12-,16-15-

InChI key: InChIKey=RCRCTBLIHCHWDZ-DOFZRALJSA-N

SMILES: O(C(CO)CO)C(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O

Synonyms:

• 1,3-Dihydroxypropan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate
• 2-Arachidonylglycerol
• 2-Monoarachidonoylglycerol
• 5,8,11,14-Eicosatetraenoic acid, 2-hydroxy-1-(hydroxymethyl)ethyl ester, (5Z,8Z,11Z,14Z)-
• 5,8,11,14-Eicosatetraenoic acid, 2-hydroxy-1-(hydroxymethyl)ethyl ester, (all-Z)-
• 2-AG
• 2-Arachidonyl glycerol solution in acetonitrile
• 2-ARACHIDONOYLGLYCEROL
• 2-Arachidonylglycerol (acetonitrile solution)
• 5Z,8Z,11Z,14Z-EICOSATETRAENOIC ACID, 2-GLYCERYL ESTER
• 2-Arachidonyl Glycerol (90%)
• 2-Arachidonyl Glycerol (~70%)
• (5Z,8Z,11Z,14Z)-1,3-Dihydroxypropan-2-yl icosa-5,8,11,14-tetraenoate
• (all-Z)-5,8,11,14-Eicosatetraenoic Acid 2-Hydroxy-1-(hydroxyMethyl)ethyl Ester
• NOLADIN
• (5Z,8Z,11Z,14Z)-5,8,11,14-Eicosatetraenoicacid
• 2-Hydroxy-1-(hydroxymethyl)ethylester
• (5Z,8Z,11Z,14Z)-5,8,11,14-EICOSATETRAENOIC ACID, 2-HYDROXY-1-(HYDROXYMETHYL)ETHYL ESTER

2-Monoarachidonin

CAS: 53847-30-6

Formula: C23H38O4

Purity: >98%

Color and Shape: Liquid

Molecular weight: 378.55

Ref: 48-31-2042

2-Arachidonoyl Glycerol (1% in Acetonitrile)

CAS: 53847-30-6

Formula: C₂₃H₃₈O₄

Color and Shape: Colorless to Almost colorlessclear liquid

Molecular weight: 378.55

Ref: 3B-A3490

2-Arachidonyl glycerol

CAS: 53847-30-6

2-Arachidonyl glycerol is an endogenous cannabinoid receptor agonist, which is derived from arachidonic acid present in cellular membranes. It functions as a signaling lipid and plays a critical role in the endocannabinoid system, which is a complex network of receptors and ligands involved in maintaining physiological homeostasis. Sourced primarily from membrane phospholipids, 2-Arachidonyl glycerol acts by binding to cannabinoid receptors, CB1 and CB2, located in the central and peripheral nervous systems. This binding modulates various signaling pathways, influencing processes like inflammation, pain perception, and neuroprotection. Its uses and applications are extensive in scientific research, especially in exploring mechanisms of neurodegenerative diseases, pain management, and immune response regulation. 2-Arachidonyl glycerol also serves as a vital tool for understanding the physiological roles of endocannabinoids and their potential therapeutic implications.

Formula: C₂₃H₃₈O₄

Purity: Min. 95%

Color and Shape: Clear Liquid

Molecular weight: 378.55 g/mol

Ref: 3D-FA17965

2-Arachidonoylglycerol

CAS: 53847-30-6

In the central nervous system, 2-Arachidonoylglycerol is a second endogenous cannabinoid ligand

Formula: C₂₃H₃₈O₄

Purity: 95%

Color and Shape: Liquid

Molecular weight: 378.55

Ref: TM-T14011

2-Arachidonyl Glycerol

CAS: 53847-30-6

Formula: C₂₃H₄₀O₃

Purity: 98%

Color and Shape: Liquid

Molecular weight: 364.5619

Ref: IN-DA003GKF