CAS 53866-33-4

17B-estradiol-D2 98 atom % D

Description:

17B-estradiol-D2, with the CAS number 53866-33-4, is a deuterated form of the natural hormone estradiol, which is a key estrogen in the human body. The "D2" designation indicates that two hydrogen atoms in the molecule have been replaced with deuterium, a stable isotope of hydrogen. This modification can enhance the stability and tracking of the compound in various biochemical studies. The substance retains the core characteristics of estradiol, including its role in regulating various physiological processes such as reproductive functions, bone density, and cardiovascular health. As a synthetic derivative, 17B-estradiol-D2 is often used in research applications, particularly in studies involving hormone metabolism and pharmacokinetics. Its high purity level, indicated by "98 atom % D," suggests that it is suitable for precise analytical applications, including mass spectrometry. Overall, this compound serves as a valuable tool in both clinical and laboratory settings for understanding estrogen-related pathways and effects.

Formula: C₁₈H₂₂D₂O₂

InChI: InChI=1/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14?,15?,16?,17-,18?/m0/s1/i3D,10D

SMILES: CC12CCC3c4cc(c(c(c4CCC3C1CC[C@@H]2O)[2H])O)[2H]

Synonyms:

• Estra-1,3,5(10)-triene-2,4-D2-3,17-diol, (17-beta)-
• 2,4-Dideuterioestradiol
• (17beta)-(2,4-~2~H_2_)estra-1,3,5(10)-triene-3,17-diol

17β-Estradiol-2,4-d2

CAS: 53866-33-4

Purity: 98 atom % D

Color and Shape: White Solid

Molecular weight: 274.40

Ref: 3U-D5432

17β-Estradiol-2,4-d2

CAS: 53866-33-4

17β-Estradiol-2,4-d2 is a deuterated compound of 17β-Estradiol. 17β-Estradiol has a CAS number of 50-28-2. Estradiol is an Estrogen. The mechanism of action of estradiol is as an Estrogen Receptor Agonist.

Formula: C₁₈H₂₂D₂O₂

Color and Shape: Solid

Molecular weight: 274.39

Ref: TM-TMIJ-0028

17β-Estradiol D2 (2,4-D2)

Controlled Product

CAS: 53866-33-4

Formula: C₁₈D₂H₂₂O₂

Color and Shape: Neat

Molecular weight: 274.39

Ref: 04-C13213102

17β-Estradiol-2,4-d2

Controlled Product

CAS: 53866-33-4

Applications 17beta-Estradiol-2,4-d2 (CAS# 53866-33-4) is a useful isotopically labeled research compound.

Formula: C₁₈D₂H₂₂O₂

Color and Shape: Neat

Molecular weight: 274.39

Ref: TR-E888011

17β-Estradiol-d2

Controlled Product

CAS: 53866-33-4

17-Estradiol-3,17-diol (17-E2) is the most potent estrogen found in humans. It has been shown to be able to stimulate the growth of breast cancer cells and is a known carcinogen in animals. 17-E2 is metabolized by cytochrome P450 enzymes into catechol estrogens, which are reactive and can bind to DNA. These metabolites can cause mutations that lead to cancer. Analysis of human breast tissue has revealed that 17-E2 is synthesized from estradiol by aromatase and then converted into catechol estrogens by 17β-hydroxysteroid dehydrogenase type 1. 17-E2 also binds to estrogen receptors, which may be linked with the development of certain cancers. The presence of 17-E2 in the environment has been linked with an increased risk for cancer in humans, as it can enter the body through water or food contaminated with waste products.

Formula: C₁₈H₂₂D₂O₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 274.39 g/mol

Ref: 3D-FE170247