CAS 53882-12-5

Lodoxamide

Description:

Lodoxamide, with the CAS number 53882-12-5, is a chemical compound primarily used as an anti-allergic agent. It belongs to the class of compounds known as mast cell stabilizers, which function by inhibiting the release of histamine and other inflammatory mediators from mast cells. This action helps alleviate symptoms associated with allergic reactions, such as conjunctivitis and rhinitis. Lodoxamide is typically administered in the form of eye drops for ocular conditions or as a nasal spray for respiratory allergies. The compound is characterized by its relatively low solubility in water, which influences its formulation and delivery methods. Additionally, it has a specific molecular structure that contributes to its pharmacological properties, including its ability to selectively target mast cells. Safety and efficacy profiles have been established through clinical studies, making it a valuable option in allergy management. As with any medication, potential side effects may occur, and it is essential for users to consult healthcare professionals for appropriate use.

Formula: C₁₁H₆ClN₃O₆

InChI: InChI=1S/C11H6ClN3O6/c12-7-5(14-8(16)10(18)19)1-4(3-13)2-6(7)15-9(17)11(20)21/h1-2H,(H,14,16)(H,15,17)(H,18,19)(H,20,21)

InChI key: InChIKey=RVGLGHVJXCETIO-UHFFFAOYSA-N

SMILES: N(C(C(O)=O)=O)C1=C(Cl)C(NC(C(O)=O)=O)=CC(C#N)=C1

Synonyms:

• 2,2'-[(2-Chloro-5-Cyanobenzene-1,3-Diyl)Diimino]Bis(Oxoacetic Acid)
• 2,2′-((2-Chloro-5-Cyano-1,3-Phenylene)Bis(Azanediyl))Bis(2-Oxoacetic Acid)
• 2,2′-[(2-Chloro-5-cyano-1,3-phenylene)diimino]bis[2-oxoacetic acid]
• 2-[2-Chloro-5-cyano-3-(oxaloamino)anilino]-2-oxoacetic acid
• Acetic acid, 2,2'-((2-chloro-5-cyano-1,3-phenylene)diimino)bis(2-oxo-
• Lodoxamida
• Lodoxamida [INN-Spanish]
• Lodoxamide [INN:BAN]
• Lodoxamidum
• Lodoxamidum [INN-Latin]
• N,N'-(2-Chlor-5-cyan-3-phenylen)dioxamsaeure
• Thilomide
• Unii-Spu695Od73

2-[2-chloro-5-cyano-3-(oxaloamino)anilino]-2-oxoacetic acid

CAS: 53882-12-5

Formula: C₁₁H₆ClN₃O₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 311.6348

Ref: IN-DA003AEL

Lodoxamide

CAS: 53882-12-5

Lodoxamide

Purity: ≥98%

Molecular weight: 311.63g/mol

Ref: 54-BUP13264

Lodoxamide

CAS: 53882-12-5

Lodoxamide (Lodoxamidum) is an antiallergic drug acting as a mast-cell stabilizer. It is effective in the treatment of asthma and allergic conjunctivitis.

Formula: C₁₁H₆ClN₃O₆

Purity: 99.13% - 99.81%

Color and Shape: Solid

Molecular weight: 311.63

Ref: TM-T4566

Lodoxamide

CAS: 53882-12-5

Lodoxamide is a type of ophthalmic medication known as a mast cell stabilizer, which is chemically synthesized from non-steroidal structures. It works by inhibiting the degranulation of sensitized mast cells and subsequent release of inflammatory mediators such as histamine. This action is achieved through the stabilization of the cell membrane of mast cells, thus preventing cellular activation.

Formula: C₁₁H₆ClN₃O₆

Purity: Min. 95 Area-%

Molecular weight: 311.63 g/mol

Ref: 3D-FL180660

Lodoxamide-15N2,d2

Controlled Product

CAS: 53882-12-5

Applications Lodoxamide-15N2,d2 is the labelled form of Lodoxamide which is an antiallergic drug that acts as a mast cell stabilizer. It is effective in the treatment of allergic conjunctivitis and in decreasing vascular permeability.
References Ciprandi, G., et al.: Allergy, 51(12), 946-951 (1996); Bayer, Atilla., et al.: Ophthalmologica, 217(2), 119-123 (2003)

Formula: C₁₁H₄D₂ClN₁₅N₂O₆

Color and Shape: Neat

Molecular weight: 315.63

Ref: TR-L469367

Lodoxamide

Controlled Product

CAS: 53882-12-5

Stability Hygroscopic
Applications Lodoxamide is an antiallergic drug that acts as a mast cell stabilizer. It is effective in the treatment of allergic conjunctivitis and in decreasing vascular permeability.
References Ciprandi, G., et al.: Allergy, 51(12), 946-951 (1996); Bayer, Atilla., et al.: Ophthalmologica, 217(2), 119-123 (2003)

Formula: C₁₁H₆ClN₃O₆

Color and Shape: Neat

Molecular weight: 311.63

Ref: TR-L469365