CAS 53924-05-3

7-Chloroindole

Description:

7-Chloroindole is an organic compound characterized by its indole structure, which consists of a fused benzene and pyrrole ring, with a chlorine atom substituted at the 7-position. This substitution influences its chemical reactivity and properties. The compound typically appears as a solid at room temperature and is known for its potential applications in medicinal chemistry, particularly in the development of pharmaceuticals and agrochemicals. 7-Chloroindole exhibits moderate solubility in organic solvents, while its solubility in water is limited. The presence of the chlorine atom can enhance its biological activity and lipophilicity, making it a subject of interest in various chemical research fields. Additionally, 7-Chloroindole can participate in various chemical reactions, including electrophilic substitutions and nucleophilic attacks, due to the electron-rich nature of the indole ring. Safety data indicates that, like many halogenated compounds, it should be handled with care, as it may pose health risks upon exposure. Overall, 7-Chloroindole is a versatile compound with significant implications in synthetic and medicinal chemistry.

Formula: C₈H₆ClN

InChI: InChI=1S/C8H6ClN/c9-7-3-1-2-6-4-5-10-8(6)7/h1-5,10H

InChI key: InChIKey=WMYQAKANKREQLM-UHFFFAOYSA-N

SMILES: ClC1=C2C(=CC=C1)C=CN2

Synonyms:

• 1H-Indole, 7-chloro-
• 7-chloro-1H-indole
• Indole, 7-chloro-
• 7-Chloroindole

7-Chloroindole

CAS: 53924-05-3

Formula: C₈H₆ClN

Purity: >98.0%(GC)

Color and Shape: White to Light yellow to Dark green powder to crystal

Molecular weight: 151.59

Ref: 3B-C2436

7-Chloroindole, 98%

CAS: 53924-05-3

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₈H₆ClN

Purity: 98%

Molecular weight: 151.6

Ref: 02-L17637

1H-Indole, 7-chloro-

CAS: 53924-05-3

Formula: C₈H₆ClN

Purity: 98%

Color and Shape: Solid

Molecular weight: 151.5929

Ref: IN-DA00I9MI

7-Chloroindole

CAS: 53924-05-3

Formula: C₈H₆ClN

Molecular weight: 151.60

Ref: 7W-GK9503

7-Chloro-1H-indole

CAS: 53924-05-3

7-Chloro-1H-indole

Formula: C₈H₆ClN

Purity: ≥95%

Color and Shape: brown powder

Molecular weight: 151.59g/mol

Ref: 54-OR3666

7-Chloroindole

CAS: 53924-05-3

7-Chloroindole is a potent compound that inhibits bacterial growth. It has been shown to inhibit the growth of tumour cell lines at submicromolar concentrations, with an IC50 of 0.5 µM. 7-Chloroindole also strongly inhibits the growth of Staphylococcus aureus, with an IC50 of 0.1 µM. This compound does not cause cell death by caspase-independent pathways, but rather induces a dry weight increase and surface methodology changes in cells treated with this compound. 7-Chloroindole belongs to the class of compounds known as carotenoids and has been shown to have a neutral pH optimum. It is formed through an enzymatic reaction involving two molecules of malonyl-CoA and one molecule each of acetate and chlorophyllide a.

Formula: C₈H₆ClN

Color and Shape: Powder

Molecular weight: 151.59 g/mol

Ref: 3D-FC52475

7-Chloroindole

CAS: 53924-05-3

Formula: C₈H₆ClN

Purity: 98%

Color and Shape: White powder

Molecular weight: 151.59

Ref: 10-F040176