CAS 53936-56-4

Phenol, 4-[(tetrahydro-2H-pyran-2-yl)oxy]-

Description:

Phenol, 4-[(tetrahydro-2H-pyran-2-yl)oxy]- is an organic compound characterized by the presence of a phenolic hydroxyl group (-OH) attached to a tetrahydro-2H-pyran moiety. This compound features a phenol ring, which contributes to its aromatic properties, and the tetrahydropyran group, which introduces a cyclic ether structure. The presence of the ether linkage enhances its solubility in organic solvents while maintaining some degree of polarity due to the hydroxyl group. This compound is typically colorless to pale yellow and may exhibit a mild aromatic odor. It is important in various chemical applications, including as an intermediate in organic synthesis and potentially in the development of pharmaceuticals or agrochemicals. Safety data indicates that, like many phenolic compounds, it may pose risks such as skin irritation or toxicity if ingested or inhaled, necessitating appropriate handling and safety measures in laboratory or industrial settings.

Formula: C₁₁H₁₄O₃

InChI: InChI=1S/C11H14O3/c12-9-4-6-10(7-5-9)14-11-3-1-2-8-13-11/h4-7,11-12H,1-3,8H2

InChI key: GFBCWCDNXDKFRH-UHFFFAOYSA-N

SMILES: C1CCOC(C1)OC2=CC=C(C=C2)O

Synonyms:

• 4-(Tetrahydro-2H-pyran-2-yloxy)phenol
• 4-Hydroxyphenyl tetrahydropyranyl ether
• 4-[(2-Tetrahydropyranyl)oxy]phenol
• Deoxyarbutin
• Deoxy Arbutin
• 4-[(Tetrahydro-2H-pyran-2-yl)oxy]phenol

4-(Tetrahydro-2H-pyran-2-yloxy)phenol

CAS: 53936-56-4

Formula: C₁₁H₁₄O₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 194.2271

Ref: IN-DA00I9MK

Deoxyarbutin, 10mM (in DMSO)

CAS: 53936-56-4

Deoxyarbutin, 10mM (in DMSO)

Formula: C₁₁H₁₄O₃

Purity: ≥98%, 10 mM in DMSO

Molecular weight: 194.23

Ref: 54-BUP20008

4-[(2-Tetrahydropyranyl)oxy]phenol

CAS: 53936-56-4

4-[(2-Tetrahydropyranyl)oxy]phenol

Formula: C₁₁H₁₄O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 194.22706

Ref: 54-OR471648

Deoxyarbutin

CAS: 53936-56-4

Deoxyarbutin

Purity: ≥98%

Molecular weight: 194.23g/mol

Ref: 54-BUP18116

Deoxyarbutin

CAS: 53936-56-4

Formula: C₁₁H₁₄O₃

Color and Shape: Neat

Molecular weight: 194.23

Ref: 04-C12145600

Deoxyarbutin

CAS: 53936-56-4

Formula: C₁₁H₁₄O₃

Purity: 95%~99%

Molecular weight: 194.23

Ref: BP-BP0483

Deoxyarbutin

Controlled Product

CAS: 53936-56-4

Stability Hygroscopic
Applications Deoxyarbutin acts as a skin whitening agent through the inhibition of tyrosinase. A safer alternative to the use of hydroquinone and arbutin.
References Lin, C. et al.: Int. J. Mol. Sci., 12, 5946 (2011); Hu, Z. et al.: J. Dermatol. Sci., 55, 179 (2009);

Formula: C₁₁H₁₄O₃

Color and Shape: Neat

Molecular weight: 194.23

Ref: TR-D232105

Deoxyarbutin

CAS: 53936-56-4

DeoxyArbutin(IC50=50 nM) inhibits tyrosinase activity reversibly.

Formula: C₁₁H₁₄O₃

Purity: 99.04% - 99.88%

Color and Shape: White Solid

Molecular weight: 194.23

Ref: TM-T6463

4-((Tetrahydro-2H-pyran-2-yl)oxy)phenol

CAS: 53936-56-4

Formula: C₁₁H₁₄O₃

Purity: 95%

Color and Shape: Solid

Molecular weight: 194.23

Ref: 10-F091803

Deoxyarbutin

CAS: 53936-56-4

4-((Tetrahydro-2H-pyran-2-yl)oxy)phenol

Formula: C₁₁H₁₄O₃

Purity: 98%

Molecular weight: 194.23

Ref: IN-DG223904

Deoxyarbutin

CAS: 53936-56-4

Deoxyarbutin is a natural compound found in plants, including the fruits of the bearberry plant. It is an inhibitor of tyrosinase, an enzyme that catalyzes the conversion of tyrosinase to melanin. Deoxyarbutin has been shown to be cytostatic and inhibit skin cells from producing melanin. This may be due to its ability to inhibit tyrosinase activity by binding to the hydroxyl group on tyrosine molecules.

Formula: C₁₁H₁₄O₃

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 194.23 g/mol

Ref: 3D-FD15587