CAS 5394-23-0

4,7-Dichloro-1,10-phenanthroline

Description:

4,7-Dichloro-1,10-phenanthroline is an organic compound characterized by its structure, which features a phenanthroline backbone with chlorine substituents at the 4 and 7 positions. This compound is typically a solid at room temperature and exhibits a crystalline form. It is known for its chelating properties, particularly with metal ions, making it useful in coordination chemistry and analytical applications. The presence of chlorine atoms enhances its electron-withdrawing characteristics, influencing its reactivity and solubility in various solvents. 4,7-Dichloro-1,10-phenanthroline is often employed in the synthesis of metal complexes and can serve as a ligand in coordination compounds. Additionally, it may exhibit fluorescence properties, which can be utilized in various detection methods. Safety precautions should be taken when handling this compound, as it may pose health risks if ingested or inhaled. Overall, its unique structural features and reactivity make it a valuable compound in both research and industrial applications.

Formula: C₁₂H₆Cl₂N₂

InChI: InChI=1S/C12H6Cl2N2/c13-9-3-5-15-11-7(9)1-2-8-10(14)4-6-16-12(8)11/h1-6H

InChI key: InChIKey=GIEQBYJCGYHHSU-UHFFFAOYSA-N

SMILES: ClC=1C=2C(=C3C(=CC2)C(Cl)=CC=N3)N=CC1

Synonyms:

• 1,10-Phenanthroline, 4,7-dichloro-
• 4,7-Dichloro-o-phenanthroline
• K0052
• NSC 626
• 4,7-Dichloro-1,10-phenanthroline

4,7-Dichloro-1,10-phenanthroline

CAS: 5394-23-0

Formula: C₁₂H₆Cl₂N₂

Purity: >98.0%(GC)(T)

Color and Shape: White to Almost white powder to crystaline

Molecular weight: 249.09

Ref: 3B-D5690

4,7-Dichloro-1,10-phenanthroline

CAS: 5394-23-0

Formula: C₁₂H₆Cl₂N₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 249.0954

Ref: IN-DA003KK3

4,7-Dichloro-1,10-phenanthroline

CAS: 5394-23-0

4,7-Dichloro-1,10-phenanthroline

Formula: C₁₂H₆Cl₂N₂

Purity: ≥95%

Color and Shape: yellow solid

Molecular weight: 249.10g/mol

Ref: 54-OR315158

4,7-Dichloro-1,10-phenanthroline

CAS: 5394-23-0

Formula: C₁₂H₆Cl₂N₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 249.09

Ref: 10-F327520

4,7-Dichloro-1,10-phenanthroline

CAS: 5394-23-0

4,7-Dichloro-1,10-phenanthroline is a bidentate ligand that binds to the chloride anion and has been shown to have anticancer activity against leukemia cells. This compound has also been shown to inhibit the proliferation of cervical cancer cells and chronic myeloid leukemia cells. 4,7-Dichloro-1,10-phenanthroline enhances the fluorescence of human chronic myeloid leukemia cells in a cytometry assay by increasing hydrogen bonding between the cell membrane and fluorophore. This enhancement effect was seen at concentrations of 0.01 μM and higher. 4,7-Dichloro-1,10-phenanthroline also binds to DNA and has been shown to be effective against cancer cells in a luminescent human chronic myeloid leukemia (MRC5) assay.

Formula: C₁₂H₆Cl₂N₂

Purity: Min. 95%

Molecular weight: 249.09 g/mol

Ref: 3D-FAA39423