CAS 53948-51-9

Bisnortilidine

Description:

Bisnortilidine, identified by its CAS number 53948-51-9, is a chemical compound that belongs to the class of organic compounds known as amines. It is characterized by the presence of multiple nitrogen atoms, which contribute to its basicity and potential reactivity. The structure of Bisnortilidine typically features a complex arrangement of carbon and nitrogen atoms, influencing its physical and chemical properties. This compound may exhibit solubility in various organic solvents, depending on its specific functional groups and molecular structure. Bisnortilidine is often studied for its potential applications in pharmaceuticals and organic synthesis, where its unique properties can be harnessed for the development of new materials or therapeutic agents. As with many chemical substances, safety precautions should be observed when handling Bisnortilidine, as it may pose health risks or environmental hazards. Further research is essential to fully understand its behavior, reactivity, and potential applications in various fields of chemistry and industry.

Formula: C₁₅H₁₉NO₂

InChI: InChI=1/C15H19NO2/c1-2-18-14(17)15(11-7-6-10-13(15)16)12-8-4-3-5-9-12/h3-6,8-10,13H,2,7,11,16H2,1H3/t13-,15+/s2

InChI key: InChIKey=BTKAMSWFNMGLGM-UYWMCZCJNA-N

SMILES: C(OCC)(=O)[C@]1([C@H](N)C=CCC1)C2=CC=CC=C2

Synonyms:

• 3-Cyclohexene-1-carboxylic acid, 2-amino-1-phenyl-, ethyl ester, (1R,2S)-rel-
• 3-Cyclohexene-1-carboxylic acid, 2-amino-1-phenyl-, ethyl ester, trans-(+-)-
• Bisnortilidine

Bisnortilidine

Controlled Product

CAS: 53948-51-9

Applications A metabolite of Tilidine (T440300(M)), which is a controlled substance (opiate) and a analgesic. Tilidine is used in clinical trial in comparison with Nefopam. Tilidine is one of the most widely used narcotics in Germany and Belgium.
References Hengy, H., et al.: J. Pharm. Sci., 67, 1765 (1978); Cordonnier, J., et al.: J. Anal. Toxicol., 11, 144 (1987); Hajda, J., et al.: J. Clin. Pharmacol., 42, 1257 (2002); Vollmer, K.-O., et al.: Arzneim.-Forsch., 20, 990 (1970); Abeloos, J., et al.: Acta Anaesthesiol. Belg., 34, 283 (1983); Van Cauwenberge, H., et al.: Int. J. Clin. Pharmacol. Res., 12, 1 (1992)

Formula: C₁₅H₁₉NO₂

Color and Shape: Neat

Molecular weight: 245.32

Ref: TR-B508850

Bisnortilidine (1 mg/ml in Acetonitrile)

Controlled Product

CAS: 53948-51-9

Formula: C₁₅H₁₉NO₂

Color and Shape: Colourless

Molecular weight: 245.32

Ref: TR-KIT3265

Bisnortilidine

Controlled Product

CAS: 53948-51-9

Bisnortilidine is a prodrug that is hydrolyzed to form nortilidine in vivo. It has been shown to have a matrix effect on the plasma concentration-time curve, which is important for clinical relevance. The rate of formation of bisnortilidine can be determined by measuring the amount of hydrochloric acid present in human liver tissue. Bisnortilidine has a low solubility, and therefore must be dissolved in water before injection into the femoral vein. A chromatographic method has been developed to measure bisnortilidine concentrations in plasma samples. Bisnortilidine can be measured using analytical methods that are based on the concentration-time curve and excretory organs such as urine samples.

Formula: C₁₅H₁₉NO₂

Purity: Min. 95%

Color and Shape: Clear Liquid

Molecular weight: 245.32 g/mol

Ref: 3D-FB18819