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CAS 53950-14-4

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Cefalexin lysine salt

Description:
Cefalexin lysine salt is a pharmaceutical compound derived from cefalexin, a first-generation cephalosporin antibiotic. It is primarily used to treat bacterial infections by inhibiting cell wall synthesis in susceptible bacteria. The lysine salt form enhances the solubility and stability of cefalexin, making it more bioavailable for therapeutic use. Cefalexin itself is effective against a range of gram-positive and some gram-negative bacteria, making it useful for treating infections such as respiratory tract infections, skin infections, and urinary tract infections. The compound typically appears as a white to off-white crystalline powder and is soluble in water, which facilitates its formulation in oral and injectable dosage forms. Its pharmacokinetics include rapid absorption after oral administration, with peak plasma concentrations occurring within a few hours. Common side effects may include gastrointestinal disturbances, allergic reactions, and, in rare cases, more severe hypersensitivity reactions. As with any antibiotic, appropriate use is crucial to minimize the risk of developing antibiotic resistance.
Formula:C16H17N3O4S·C6H14N2O2
InChI:InChI=1S/C16H17N3O4S.C6H14N2O2/c1-8-7-24-15-11(14(21)19(15)12(8)16(22)23)18-13(20)10(17)9-5-3-2-4-6-9;7-4-2-1-3-5(8)6(9)10/h2-6,10-11,15H,7,17H2,1H3,(H,18,20)(H,22,23);5H,1-4,7-8H2,(H,9,10)/t10-,11-,15-;5-/m10/s1
InChI key:InChIKey=CSXICSKZWGBACI-SSDGIDNNSA-N
SMILES:O=C1N2[C@@]([C@@H]1NC([C@H](N)C3=CC=CC=C3)=O)(SCC(C)=C2C(O)=O)[H].[C@H](CCCCN)(C(O)=O)N
Synonyms:
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[(aminophenylacetyl)amino]-3-methyl-8-oxo-, [6R-[6α,7β(R*)]]-, compd. with L-lysine (1:1)
  • Cefalexin lysine salt
  • L-Lysine, mono[[6R-[6α,7β(R*)]]-7-[(aminophenylacetyl)amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate]
  • L-Lysine, (6R,7R)-7-[[(2R)-2-amino-2-phenylacetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate (1:1)
  • L-Lysine mono((6R-(6alpha,7beta(R*)))-7-((aminophenylacetyl)amino)-3-methyl-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylate)
  • (6R,7R)-7-{[amino(phenyl)acetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid - L-lysine (1:1)
  • L-Lysine, mono[(6R,7R)-7-[[(2R)-aminophenylacetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate]
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