CAS 5398-36-7

Ethyl 2-amino-4-thiazolecarboxylate

Description:

Ethyl 2-amino-4-thiazolecarboxylate is an organic compound characterized by its thiazole ring, which is a five-membered heterocyclic structure containing sulfur and nitrogen. This compound features an ethyl ester functional group, contributing to its reactivity and solubility in organic solvents. The presence of the amino group (-NH2) enhances its potential for forming hydrogen bonds, making it a versatile intermediate in organic synthesis. Ethyl 2-amino-4-thiazolecarboxylate is often utilized in the synthesis of various pharmaceuticals and agrochemicals due to its biological activity, particularly in the development of antimicrobial and anti-inflammatory agents. Its molecular structure allows for various substitution reactions, making it a valuable building block in medicinal chemistry. Additionally, it is important to handle this compound with care, as it may pose health risks if ingested or inhaled, and proper safety protocols should be followed during its use in laboratory settings.

Formula: C₆H₈N₂O₂S

InChI: InChI=1S/C6H8N2O2S/c1-2-10-5(9)4-3-11-6(7)8-4/h3H,2H2,1H3,(H2,7,8)

InChI key: InChIKey=XHFUVBWCMLLKOZ-UHFFFAOYSA-N

SMILES: C(OCC)(=O)C1=CSC(N)=N1

Synonyms:

• 2-Amino-1,3-Thiazole-4-Carboxylate
• 2-Amino-1,3-thiazole-4-carboxylic acid ethyl ester
• 2-Amino-4-(ethoxycarbonyl)-1,3-thiazole
• 2-Amino-4-Thiazolecarboxylic acid ethyl ester
• 2-Amino-4-ethoxycarbonylthiazole
• 2-Aminothiazol-4-carboxylic acid ethyl ester
• 2-Aminothiazole-4-carboxylic Acid Ethyl Ester
• 2-Imino-2,3-dihydro-thiazole-4-carboxylic acid ethyl ester
• 4-Thiazolecarboxylic acid, 2-amino-, ethyl ester
• Ethyl 2-amino-1,3-thiazole-4-carboxylate
• Ethyl 2-amino-4-thiazolecarboxylate
• NSC 43547

Ethyl 2-Aminothiazole-4-carboxylate

CAS: 5398-36-7

Formula: C₆H₈N₂O₂S

Purity: >98.0%(GC)(T)

Color and Shape: White to Orange to Green powder to crystal

Molecular weight: 172.20

Ref: 3B-E1215

Ethyl 2-aminothiazole-4-carboxylate, 98%

CAS: 5398-36-7

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₆H₈N₂O₂S

Purity: 98%

Color and Shape: Powder, Pale cream to cream to pale yellow

Molecular weight: 172.20

Ref: 02-H30634

Ethyl 2-aminothiazole-4-carboxylate

CAS: 5398-36-7

Formula: C₆H₈N₂O₂S

Purity: 97%

Color and Shape: Solid

Molecular weight: 172.2049

Ref: IN-DA003Q38

Ethyl 2-amino-1,3-thiazole-4-carboxylate

CAS: 5398-36-7

Ethyl 2-amino-1,3-thiazole-4-carboxylate

Formula: C₆H₈N₂O₂S

Purity: ≥95%

Color and Shape: yellow powder

Molecular weight: 172.20g/mol

Ref: 54-OR10473

Ethyl 2-aminothiazole-4-carboxylate

CAS: 5398-36-7

Formula: C₆H₈N₂O₂S

Purity: 97%

Color and Shape: Solid

Molecular weight: 172.2

Ref: 10-F017326

Ethyl 2-Amino-1,3-thiazole-4-carboxylate

Controlled Product

CAS: 5398-36-7

Formula: C₆H₈N₂O₂S

Color and Shape: Neat

Molecular weight: 172.2

Ref: TR-E678465

Ethyl 2-amino-thiazole-4-carboxylate

CAS: 5398-36-7

Ethyl 2-amino-thiazole-4-carboxylate (ETAC) is an inhibitor of protein synthesis. It binds to the dna and inhibits transcription, leading to cell death by inhibiting the production of proteins vital for cell division. ETAC has been shown to have cytotoxic activity against cancer cells and hemolytic activity. It also has a strong fluorescence probe property, which may be used in cancer diagnosis. ETAC can inhibit protein synthesis in cells that are resistant to other antimicrobial agents and platinum-based chemotherapy, making it a potential treatment for these infections. The pharmacokinetic properties of ETAC are not well studied but it is excreted through urine, suggesting that it is hydrophilic and may be metabolized with glucuronidation or sulfation. The molecular modeling study suggests that the hydrogen bond between ETAC and the dna phosphate group may explain its inhibitory effects on DNA synthesis.

Formula: C₆H₈N₂O₂S

Purity: Min. 99.0 Area-%

Molecular weight: 172.21 g/mol

Ref: 3D-FE43670

Acotiamide Impurity 3

CAS: 5398-36-7

Formula: C₆H₈N₂O₂S

Molecular weight: 172.2

Ref: ST-EA-CP-A45005