CAS 53994-73-3

Cefaclor

Description:

Cefaclor is a semisynthetic antibiotic belonging to the cephalosporin class, primarily used to treat bacterial infections. It is effective against a range of gram-positive and some gram-negative bacteria, making it useful for respiratory tract infections, skin infections, and urinary tract infections. Cefaclor is characterized by its beta-lactam structure, which is essential for its antibacterial activity, as it inhibits bacterial cell wall synthesis. The compound is typically administered orally and is well-absorbed in the gastrointestinal tract. Its pharmacokinetics include a relatively short half-life, necessitating multiple doses throughout the day to maintain effective therapeutic levels. Common side effects may include gastrointestinal disturbances, allergic reactions, and, in rare cases, more severe hypersensitivity reactions. Cefaclor is generally contraindicated in individuals with a known allergy to cephalosporins or penicillins. As with all antibiotics, it is crucial to complete the prescribed course to prevent the development of antibiotic resistance.

Formula: C₁₅H₁₄ClN₃O₄S

InChI: InChI=1S/C15H14ClN3O4S/c16-8-6-24-14-10(13(21)19(14)11(8)15(22)23)18-12(20)9(17)7-4-2-1-3-5-7/h1-5,9-10,14H,6,17H2,(H,18,20)(H,22,23)/t9-,10-,14-/m1/s1

InChI key: InChIKey=QYIYFLOTGYLRGG-GPCCPHFNSA-N

SMILES: O=C1N2[C@@]([C@@H]1NC([C@H](N)C3=CC=CC=C3)=O)(SCC(Cl)=C2C(O)=O)[H]

Synonyms:

• (6R,7R)-7-((R)-2-Amino-2-phenylacetamido)-3-chloro-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid
• (6R,7R)-7-{[(2R)-2-amino-2-phenylacetyl]amino}-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• (6R,7R)-7-{[(2R)-2-amino-2-phenylacetyl]amino}-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hydrate (1:1)
• (6S,7R)-7-[[(2R)-2-amino-2-phenyl-acetyl]amino]-3-chloro-6-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• 3-Chloro-7-D-(2-phenylglycinamido)-3-cephem-4-carboxylic acid
• 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-((aminophenylacetyl)amino)-3-chloro-8-oxo-, (6R-(6-alpha,7-beta(R*)))-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[(aminophenylacetyl)amino]-3-chloro-8-oxo-, [6R-[6α,7β(R*)]]-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2R)-2-amino-2-phenylacetyl]amino]-3-chloro-8-oxo-, (6R,7R)-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2R)-aminophenylacetyl]amino]-3-chloro-8-oxo-, (6R,7R)-
• 7-(<span class="text-smallcaps">D</span>-2-Amino-2-phenylacetamido)-3-chloro-3-cephem-4-carboxylic acid
• 7-(D-2-Amino-2-phenylacetamido)-3-chloro-3-cephem-4-carboxylic acid
• 7-[(Aminophenylacetyl)amino]-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• Alfacet
• Ceclor
• Ceclor CD
• Ceclor MR
• Cefaclor anhydrous
• Cefaclorum
• Cephaclor
• Distaclor
• Kefral
• Lilly 99638
• Losefar
• Panoral
• Raniclor
• S 6472

Cefaclor

CAS: 53994-73-3

A second-generation cephalosporin antibiotic

Formula: C₁₅H₁₄ClN₃O₄S

Molecular weight: 367.81

Ref: 02-J64252

Cefaclor

CAS: 53994-73-3

Cefaclor

Formula: C₁₅H₁₄ClN₃O₄S

Purity: 93.5%

Color and Shape: White

Molecular weight: 367.03935

Ref: 47-792

5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,7-[[(2R)-aminophenylacetyl]amino]-3-chloro-8-oxo-, (6R,7R)-

CAS: 53994-73-3

Formula: C₁₅H₁₄ClN₃O₄S

Purity: 98%

Color and Shape: Solid

Molecular weight: 367.8074

Ref: IN-DA00I9MW

Cefaclor

CAS: 53994-73-3

Formula: C₁₅H₁₄ClN₃O₄S·xH₂O

Purity: 95.0 - 102.0 % (dried basis)

Color and Shape: White to light-yellow powder

Molecular weight: 367.81

Ref: 7W-GA0871

Cefaclor

CAS: 53994-73-3

Cefaclor

Formula: C₁₅H₁₄ClN₃O₄S

Color and Shape: almost white crystalline powder

Molecular weight: 367.81g/mol

Ref: 54-BIM0109

Cefaclor

CAS: 53994-73-3

Formula: C₁₅H₁₄ClN₃O₄S

Color and Shape: Off-White Solid

Molecular weight: 367.80

Ref: 4Z-C-662

Cefaclor, USP grade

CAS: 53994-73-3

Formula: C₁₅H₁₄ClN₃O₄S·xH₂O

Molecular weight: 367.81

Ref: 7W-GA9873

Cefaclor

Controlled Product

CAS: 53994-73-3

Formula: C₁₅H₁₄ClN₃O₄S

Color and Shape: Neat

Molecular weight: 367.81

Ref: 04-C11062550

Cefaclor

CAS: 53994-73-3

Cefaclor (Panoral) is a cephalosporin antibiotic.

Formula: C₁₅H₁₄ClN₃O₄S

Purity: 99.03% - 99.98%

Color and Shape: Solid

Molecular weight: 367.81

Ref: TM-T6436

Cefaclor RS

CAS: 53994-73-3

Color and Shape: White To Yellow-White Solid Crystalline Powder

Ref: 2K-7000370021

Cefaclor-d5 Hydrate

Controlled Product

CAS: 1426173-90-1, 53994-73-3

Applications Second-generation labelled cephalosporin antibiotic. Antibacterial.
References Gray, B.M., et al.: Antimicrob. Agents Chemother., 13, 988 (1978), Lorenz, L.J., et al.: Anal. Profiles Drug Subs., 9, 107 (1980), Hori, R., et al.: J. Pharm. Pharmacol., 40, 646 (1988),

Formula: C₁₅H₉D₅ClN₃O₄S•x(H₂O)

Color and Shape: Neat

Molecular weight: 372.84 + x(18.02)

Ref: TR-C235252

Cefaclor

CAS: 53994-73-3

Inhibitor of bacterial cell wall biogenesis; cephalosporin

Formula: C₁₅H₁₄ClN₃O₄S

Purity: Min. 95 Area-%

Color and Shape: White Powder

Molecular weight: 367.81 g/mol

Ref: 3D-AC34967

Cefaclor (CFC), 95%

CAS: 53994-73-3

Formula: C₁₅H₁₄ClN₃O₄S

Purity: min. 95%

Color and Shape: White to Pale yellow, Powder, Clear

Molecular weight: 367.8

Ref: SR-92063

Cefaclor

CAS: 53994-73-3

Formula: C₁₅H₁₄ClN₃O₄S

Purity: 98%

Color and Shape: Solid

Molecular weight: 367.8

Ref: 10-F463447

Descarboxyl Carbonyl Cefaclor

Controlled Product

CAS: 53994-73-3

Formula: C₁₅H₁₄ClN₃O₅S

Color and Shape: Neat

Molecular weight: 383.807

Ref: TR-D338740