CAS 54-05-7
:Chloroquine
Description:
Chloroquine is a synthetic compound primarily known for its use as an antimalarial drug. It belongs to the class of 4-aminoquinolines and is characterized by its ability to interfere with the growth of parasites in red blood cells. The chemical formula of chloroquine is C18H26ClN3, and it has a molecular weight of approximately 319.87 g/mol. Chloroquine is typically presented as a white to off-white crystalline powder that is soluble in water and exhibits a bitter taste. Its mechanism of action involves the inhibition of heme polymerization within the malaria parasite, leading to toxic accumulation of heme. In addition to its antimalarial properties, chloroquine has also been investigated for potential antiviral effects and as an anti-inflammatory agent in conditions like rheumatoid arthritis and lupus. However, its use has been associated with various side effects, including gastrointestinal disturbances and retinal toxicity with long-term use. Due to the emergence of drug-resistant malaria strains, chloroquine's efficacy has diminished in some regions, prompting the exploration of alternative treatments.
Formula:C18H26ClN3
InChI:InChI=1/C18H26ClN3/c1-4-22(5-2)12-6-7-14(3)21-17-10-11-20-18-13-15(19)8-9-16(17)18/h8-11,13-14H,4-7,12H2,1-3H3,(H,20,21)/t14-/m0/s1
InChI key:InChIKey=WHTVZRBIWZFKQO-UHFFFAOYSA-N
SMILES:N(C(CCCN(CC)CC)C)C=1C2=C(N=CC1)C=C(Cl)C=C2
Synonyms:- (4S)-N~4~-(7-chloroquinolin-4-yl)-N~1~,N~1~-diethylpentane-1,4-diamine
- 1,4-Pentanediamine, N4-(7-chloro-4-quinolinyl)-N1,N1-diethyl-
- 1,4-Pentanediamine, N<sup>4</sup>-(7-chloro-4-quinolinyl)-N<sup>1</sup>,N<sup>1</sup>-diethyl-
- 4-(7-Chloro-4-Quinolylamino)Pentyldiethylamine
- 7-Chloro-4-[[4-(diethylamino)-1-methylbutyl]amino]quinoline
- Aralen
- Artrichin
- Bipiquin
- Capquin
- Chloraquine
- Chloro Quine Phosphate
- Chlorochin
- Chlorolex
- Chloroquin
- Cloquin
- Cloroquina
- E-Vivax
- Maliago
- N<sup>4</sup>-(7-Chloro-4-quinolinyl)-N<sup>1</sup>,N<sup>1</sup>-diethyl-1,4-pentanediamine
- Nivaquinp
- Nsc 187208
- Premoquine
- Quinoline, 7-chloro-4-[[4-(diethylamino)-1-methylbutyl]amino]-
- Reumachlor
- Ronaquine
- Rp 3377
- ST 121 (pharmaceutical)
- St 121
- N4-(7-Chloro-4-quinolinyl)-N1,N1-diethyl-1,4-pentanediamine
- Quinagamin
- Chlorquin
- Chloroquina
- 3377 RP
- Cocartrit
- Avlochlor
- Arthrochin
- Imagon
- Sopaquin
- Chingamin
- 7-chloro-4-(4-diethylamino-1-methylbutylamino)quinoline
- WIN 244
- Bemaphate
- Quinachlor
- Nivaquine B
- -[7-Chloro-4-quinolinyl]-N',N'-diethyl-1,4-pentanediamine
- Lapaquin
- SN 6718
- Cidanchin
- Quinoscan
- 7-CHLORO-4-(4-DIMETHYLAMINO-1-METHYLBUTYLAMINO)QUINOLINE
- Delagil
- Diphenylhydramine
- Nivaquine
- Bemasulph
- Elestol
- w7618
- 7-chloro-4-((4-(diethylamino)-1-methylbutyl)amino)-quinolin
- n(4)-(7-chloro-4-quinolinyl)-n(1),n(1)-diethyl-4-pentanediamine
- Resoquine
- Tanakan
- nivaquineb
- Arechin
- SN 7618
- Benaquin
- W 7618
- Mesylith
- Silbesan
- Sanoquin
- Quinercyl
- N(sup4)-(7-chloro-4-quinolinyl)-N(sup1),N(sup1)-diethyl-1,4-pentanediamine
- Avloclor
- 4-(4-Diethylamino-1-methylbutylamino)-7-chloroquinoline
- Clorochina
- CHLOROQUINE
- 3377 RP opalate
- 4-(4-Diethylamino-1-methylbntyla-mino)-7-chloroquinoline
- Nivaquine [as sulfate]
- N
- Reumaquin
- Tresochin
- Malaquin
- 4
- Neochin
- Malarex
- Dichinalex
- Chloroquine (base and/or unspecified salts)
- Resochin
- Quingamine
- (7-chloro-4-(4-diethylamino-1-methylbutylamino)-quinoline
- win244
- Cloroquine
- Nivachine
- Amokin
- Resochen
- rp3377
- Quinagamine
- Chemochin
- Gontochin
- 1,4-pentanediamine,n(sup4)-(7-chloro-4-quinolinyl)-n(sup1),n(sup1)-diethy
- Solprina
- sn7618
- Siragan
- Trochin
- Resoquina
- Malaren
- Chloroquinium
- N4-(7-chloroquinolin-4-yl)-N1,N1-diethylpentane-1,4-diaMine
- Bemaco
- Heliopar
- Klorokin
- Roquine
- Iroquine
- Pfizerquine
- Chlorochine
- See more synonyms
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Found 11 products.
Chloroquine
CAS:Formula:C18H26ClN3Purity:>98.0%(T)(HPLC)Color and Shape:White to Light yellow powder to lumpMolecular weight:319.887-Chloro-4-[[4-(diethylamino)-1-methylbutyl]amino]quinoline
CAS:Formula:C18H26ClN3Purity:95%Color and Shape:SolidMolecular weight:319.8721N4-(7-Chloroquinolin-4-Yl)-N1,N1-Diethylpentane-1,4-Diamine
CAS:N4-(7-Chloroquinolin-4-Yl)-N1,N1-Diethylpentane-1,4-DiamineFormula:C18H26ClN3Purity:>97%Color and Shape:SolidMolecular weight:319.87Chloroquine
CAS:Chloroquine: antimalarial, anti-inflammatory, autophagy/TLRs inhibitor, treats arthritis, effective against COVID-19 in vitro. EC50: 1.13 μM.Formula:C18H26ClN3Purity:99.5% - 99.98%Color and Shape:SolidMolecular weight:319.87Chloroquine
CAS:N4-(7-Chloroquinolin-4-yl)-N1,N1-diethylpentane-1,4-diamineFormula:C18H26ClN3Purity:95%Molecular weight:319.87Chloroquine
CAS:Applications Chloroquine used in the treatment of malaria and MDR-strains. It is a COVID19-related research product.
References Laufer, M. et al.: PLoS One., 7, e42284 (2012); Hangartner, S. et al.: Drug Test. ANal., 5, 777 (2013)Formula:C18H26ClN3Color and Shape:NeatMolecular weight:319.87Chloroquine
CAS:Chloroquine is a 4-aminoquinolone that is used to prevent and treat malaria, caused by parasitic protozoan from the Plasmodium genus. Chloroquine is are an schizonticidal agent and is a widely prescribed antimalarial compound. The antiviral activity of chloroquine in vitro has been reported in 1960’s and recent publications have brought attention to its possible benefits in the treatment of COVID-19 patients, infected with the newly emerged coronavirus (SARS-CoV-2). Current evidence shows that chloroquine inhibits SARS CoV-2 entry in host cells by interfering with endocytosis and the glycoprofile on the S-glycoprotein.Formula:C18H26ClN3Purity:Min. 95%Color and Shape:White Off-White PowderMolecular weight:319.87 g/molN4-(7-Chloroquinolin-4-yl)-N1,N1-diethylpentane-1,4-diamine
CAS:Formula:C18H26ClN3Purity:95%Color and Shape:SolidMolecular weight:319.88
![7-Chloro-4-[[4-(diethylamino)-1-methylbutyl]amino]quinoline](https://static.cymitquimica.com/products/IN/thumb/DA00DDVD.jpg)
