CAS 54-25-1

6-Azauridine

Description:

6-Azauridine, with the CAS number 54-25-1, is a nucleoside analog of uridine, where the nitrogen atom replaces the carbon atom at the 6-position of the pyrimidine ring. This modification alters its biological properties, making it of interest in various biochemical and pharmaceutical applications. 6-Azauridine exhibits antiviral activity and has been studied for its potential use in treating viral infections and certain types of cancer. The compound is soluble in water, which facilitates its use in biological studies. Its structure allows it to participate in nucleic acid metabolism, potentially interfering with RNA synthesis. Additionally, 6-Azauridine can be phosphorylated to form active triphosphate derivatives, which can be incorporated into RNA, thereby affecting the function and replication of viral genomes. As with many nucleoside analogs, the therapeutic use of 6-Azauridine may be accompanied by side effects, necessitating careful consideration in clinical applications. Overall, its unique structural characteristics and biological activities make it a compound of significant interest in medicinal chemistry and virology.

Formula: C₈H₁₁N₃O₆

InChI: InChI=1S/C8H11N3O6/c12-2-3-5(14)6(15)7(17-3)11-8(16)10-4(13)1-9-11/h1,3,5-7,12,14-15H,2H2,(H,10,13,16)/t3-,5-,6-,7-/m1/s1

InChI key: InChIKey=WYXSYVWAUAUWLD-SHUUEZRQSA-N

SMILES: O[C@H]1[C@@H](O[C@H](CO)[C@H]1O)N2C(=O)NC(=O)C=N2

Synonyms:

• 1,2,4-Triazine-3,5(2H,4H)-dione, 2-β-<span class="text-smallcaps">D</span>-ribofuranosyl-
• 2-(beta-D-ribofuranosyl)-1,2,4-triazine-3,5(2H,4H)-dione
• 2-(beta-D-ribofuranosyl)-1,2,4-triazine-3,5-diol
• 2-pentofuranosyl-1,2,4-triazine-3,5(2H,4H)-dione
• 2-β-<span class="text-smallcaps">D</span>-Ribofuranosyl-1,2,4-triazine-3,5(2H,4H)-dione
• 2-β-<span class="text-smallcaps">D</span>-Ribofuranosyl-as-triazine-3,5(2H,4H)-dione
• 6-AzUr
• 6-Azauracil 1-riboside
• 6-Azauracil-β-<span class="text-smallcaps">D</span>-riboside
• 6-Azuridine
• Azauridine
• Fsl 0296
• NSC 32074
• Rib-Azauracil
• Riboazauracil
• as-Triazine-3,5(2H,4H)-dione, 2-β-<span class="text-smallcaps">D</span>-ribofuranosyl-
• as-Triazine-3,5(2H,4H)-dione, 2-β-D-ribofuranosyl-
• 2-β-D-Ribofuranosyl-1,2,4-triazine-3,5(2H,4H)-dione

6-Azauridine

CAS: 54-25-1

Formula: C₈H₁₁N₃O₆

Purity: >99.0%(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 245.19

Ref: 3B-A0559

6-Azauridine

CAS: 54-25-1

6-Azauridine can be applied in antiviral studies. 6-azauridine inhibits de novo pyrimidine synthesis and DNA synthesis and is converted intracellularly into mono, di, and triphosphate derivatives, which incorporate into RNA and inhibit protein synthesis. It is also used as an antineoplastic antimet

Formula: C₈H₁₁N₃O₆

Molecular weight: 245.19

Ref: 02-J61309

6-Azuridine

CAS: 54-25-1

Formula: C₈H₁₁N₃O₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 245.1894

Ref: IN-DA003N34

6-Azauridine

CAS: 54-25-1

Formula: C₈H₁₁N₃O₆

Molecular weight: 245.19

Ref: 7W-GN2946

6-Azauridine

CAS: 54-25-1

6-Azauridine

Purity: 98%

Molecular weight: 245.19g/mol

Ref: 54-OR1029713

6-Azauridine

CAS: 54-25-1

6-Azauridine

Purity: ≥98%

Molecular weight: 245.19g/mol

Ref: 54-BUP18165

6-Azuridine

CAS: 54-25-1

6-Azauridine is a purine analog with antitumor effects, inhibiting DNA synthesis and inducing apoptosis in lymphatic cancers.

Formula: C₈H₁₁N₃O₆

Purity: >99.99%

Color and Shape: Solid

Molecular weight: 245.19

Ref: TM-TNU0022

6-Azauridine

CAS: 54-25-1

Inhibitor of uridine monophosphate synthase

Formula: C₈H₁₁N₃O₆

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 245.19 g/mol

Ref: 3D-NA02765

6-Azuridine

CAS: 54-25-1

Formula: C₈H₁₁N₃O₆

Purity: 98%

Molecular weight: 245.191

Ref: 10-F239460

6-Azauridine

Controlled Product

CAS: 54-25-1

Stability Hygroscopic
Applications 6-Azauridine is can be applied in antiviral studies.

Formula: C₈H₁₁N₃O₆

Color and Shape: Neat

Molecular weight: 245.19

Ref: TR-A805108