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CAS 54-31-9

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Furosemide

Description:
Furosemide, with the CAS number 54-31-9, is a potent loop diuretic commonly used in the treatment of conditions such as heart failure, hypertension, and edema. It functions by inhibiting the sodium-potassium-chloride co-transporter in the thick ascending limb of the loop of Henle in the kidneys, leading to increased excretion of sodium, chloride, and water. Furosemide is characterized by its relatively high solubility in water and its ability to produce rapid diuresis. The chemical structure of furosemide includes a sulfonamide group, which is essential for its pharmacological activity. It is typically administered orally or intravenously, and its effects can be observed within hours. Furosemide is also known for its potential side effects, which may include electrolyte imbalances, dehydration, and ototoxicity, particularly with rapid intravenous administration. Due to its effectiveness and rapid action, furosemide remains a critical medication in managing fluid overload and hypertension in clinical settings.
Formula:C12H11ClN2O5S
InChI:InChI=1S/C12H11ClN2O5S/c13-9-5-10(15-6-7-2-1-3-20-7)8(12(16)17)4-11(9)21(14,18)19/h1-5,15H,6H2,(H,16,17)(H2,14,18,19)
InChI key:InChIKey=ZZUFCTLCJUWOSV-UHFFFAOYSA-N
SMILES:C(O)(=O)C1=C(NCC2=CC=CO2)C=C(Cl)C(S(N)(=O)=O)=C1
Synonyms:
  • Aisemide
  • Aldic
  • Aluzine
  • Anfuramaide
  • Apo-Frusemide
  • Apo-Furosemide
  • Aquamide
  • Aquarid
  • Aquasin
  • Arasemide
  • See more synonyms
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