CAS 54-35-3

Penicillin G procaine

Description:

Penicillin G procaine, with the CAS number 54-35-3, is a semi-synthetic antibiotic that combines penicillin G with procaine to enhance its pharmacological properties. This compound is characterized by its broad-spectrum antibacterial activity, primarily effective against gram-positive bacteria and some gram-negative organisms. It is typically administered via intramuscular injection due to its poor oral bioavailability. The procaine component serves to prolong the action of penicillin G by slowing its release into the bloodstream, thus allowing for extended therapeutic effects. Penicillin G procaine is commonly used in the treatment of various bacterial infections, including respiratory tract infections, skin infections, and certain types of syphilis. Its formulation is designed to minimize the risk of allergic reactions associated with penicillin, although hypersensitivity can still occur in some individuals. As with other penicillins, it works by inhibiting bacterial cell wall synthesis, leading to cell lysis and death. Proper storage and handling are essential to maintain its efficacy, as it is sensitive to heat and moisture.

Formula: C₁₆H₁₈N₂O₄S·C₁₃H₂₀N₂O₂

InChI: InChI=1S/C16H18N2O4S.C13H20N2O2/c1-16(2)12(15(21)22)18-13(20)11(14(18)23-16)17-10(19)8-9-6-4-3-5-7-9;1-3-15(4-2)9-10-17-13(16)11-5-7-12(14)8-6-11/h3-7,11-12,14H,8H2,1-2H3,(H,17,19)(H,21,22);5-8H,3-4,9-10,14H2,1-2H3/t11-,12+,14-;/m1./s1

InChI key: InChIKey=WHRVRSCEWKLAHX-LQDWTQKMSA-N

SMILES: C(O)(=O)[C@@H]1N2[C@@]([C@H](NC(CC3=CC=CC=C3)=O)C2=O)(SC1(C)C)[H].C(OCCN(CC)CC)(=O)C1=CC=C(N)C=C1

Synonyms:

• (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid-2-(diethylamino)ethyl 4-aminobenzoate (1:1)
• (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid-2-(diethylamino)ethyl 4-aminobenzoate hydrate (1:1:1)
• 3,3-Dimethyl-7-Oxo-6-[(Phenylacetyl)Amino]-4-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylic Acid-2-(Diethylamino)Ethyl 4-Aminobenzoate (1:1)
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-(2-phenylacetamido)-, compd. with 2-(diethylamino)ethyl p-aminobenzoate (1:1)
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[(2-phenylacetyl)amino]- (2S,5R,6R)-, compd. with 2-(diethylamino)ethyl 4-aminobenzoate (1:1)
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]- (2S,5R,6R)-, compd. with 2-(diethylamino)ethyl 4-aminobenzoate (1:1)
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]-[2S-(2α,5α,6β)]-, compd. with 2-(diethylamino)ethyl 4-aminobenzoate (1:1)
• Abbocillin DC
• Afsillin
• Ampin-penicillin
• Aquacilina
• Aquacillin
• Aquasuspen
• Avloprocil
• Benzoic acid, 4-amino-, 2-(diethylamino)ethyl ester, mono[(2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate]
• Benzoic acid, 4-amino-, 2-(diethylamino)ethyl ester, mono[[2S-(2α,5α,6β)]-3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate]
• Benzylpenicillin
• Benzylpenicillin Procaine
• Benzylpenicillin novocaine salt
• Benzylpenicillin procaine salt
• Carepen
• Cilicaine
• Crysticillin
• Depocillin
• Despacilina
• Distaquaine
• Dorsallin AR
• Duphapen
• Duracillin
• Ethacilin
• Flo-Cillin Aqueous
• Geepenil
• Hostacillin
• Hydracillin
• Ilcocillin P
• Jenacillin O
• Kabipenin
• Ledercillin
• Lenticillin
• Mammacillin
• Masticillin
• Megapen
• Micro-Pen
• Millicillin
• Mylipen
• Neoproc
• Nopcaine
• Novocaine penicillin
• Pen 50
• Pen-Fifty
• Penaquacaine G
• Penicillin G Procaine Sterile
• Penicillin G procaine
• Penicillin procaine
• Penovet
• Pentaquacaine G
• Penzal N 300
• Premocillin
• Pro-Pen
• Procain Penicillin G
• Procaine Benzylpenicillin
• Procaine benzylpenicillin salt
• Procaine benzylpenicillinate
• Procaine penicillin (G)
• Procanodia
• Prostabillin
• Retardillin
• Sharcillin
• Vetspen
• Vitablend
• Wycillin
• Sterile Penicillin G Procaine/SodiuM3∶1 API
• Benzylpenicillinic acid, procaine
• Penicillin G procaine Benzylpenicillin procaine API
• Procaine penicillin G(fortified) USP/EP/BP
• BENZYLPENICILLIN PROCAIN SALT
• PROCAINE BENZYLPENICILLIN (PROCAINE PENICILLIN) ASSAY STANDARD BP(CRM STANDARD)
• PENICILLIN-G PROCAIN SALT
• Penicillin G Procaine/Sodium 3:1 USP/EP/BP
• PROCAINE BENZYLPENICILLIN EPP(CRM STANDARD)
• Procaine penicillin G(1% lecithin/citrate acid)
• 4-Thia-1-azabicyclo3.2.0heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-(phenylacetyl)amino- (2S,5R,6R)-, compd. with 2-(diethylamino)ethyl 4-aminobenzoate (1:1)
• (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(1-oxo-2-phenylethyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
• Penicillin G procaine +1% lecithin CP200/BP/USP/EP
• Procain-Penicillin
• PENICILLIN G PROCAINE USP/EP/BP
• Penicillin G procaine sterile CP200/BP/USP/EP
• Procaine penicillin G USP/EP/BP
• BENZYLPENICILLIN PROCAINE + POTASSIC 3:1

Procaine benzylpenicillin

CAS: 54-35-3

Procaine benzylpenicillin

Formula: C₁₃H₂₀N₂O₂ / C₁₃H₂₀N₂O₂C₁₆H₁₈N₂O₄SH₂O

Color and Shape: White Powder

Molecular weight: 236.15248

Ref: 47-295

(2S,5R,6R)-3,3-dimethyl-7-oxo-6-(2-phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; 2-(diethylamino)ethyl 4-aminobenzoate

CAS: 54-35-3

Formula: C₂₉H₃₈N₄O₆S

Purity: 98%

Molecular weight: 570.7002

Ref: IN-DA00I9MZ

Procaine penicillin G

CAS: 54-35-3

Procaine penicillin G

Purity: ≥98%

Molecular weight: 570.7g/mol

Ref: 54-BUP14921

Procaine penicillin G

CAS: 54-35-3

Procaine penicillin G treats syphilis, anthrax, oral infections, pneumonia, diphtheria, cellulitis, and bites.

Formula: C₂₉H₃₈N₄O₆S

Purity: 99.73%

Color and Shape: A White Crystalline Powder

Molecular weight: 570.7

Ref: TM-T4553

Penicillin G procaine

Controlled Product

CAS: 54-35-3

Penicillin G procaine is a form of penicillin that is commonly used to treat bacterial infections. It is a prodrug that undergoes hydrolysis in the body to release penicillin, its active form. Penicillin G procaine has been shown to be effective against Streptococcus pyogenes, which causes streptococcal pharyngitis, and other bacteria that are sensitive to penicillin. Penicillin G procaine is less toxic than other forms of penicillin and has minimal side effects. The pharmacological effects of the drug are due primarily to the inhibition of bacterial cell wall synthesis by binding to peptidoglycan precursors and blocking their cross-linking. The concentration–time curve for penicillin G procaine shows that it has a long half-life in humans, making it suitable for continuous treatment in patients with chronic infections.

Formula: C₁₆H₁₈N₂O₄S·C₁₃H₂₀N₂O₂

Purity: Min. 95%

Molecular weight: 570.7 g/mol

Ref: 3D-FP33385