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CAS 54-58-0

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2-[(2-fluorophenyl)amino]benzoic acid

Description:
2-[(2-Fluorophenyl)amino]benzoic acid, also known as flufenamic acid, is a non-steroidal anti-inflammatory drug (NSAID) that belongs to the anthranilic acid derivative class. It is characterized by its chemical structure, which features a benzoic acid moiety substituted with an amino group and a fluorophenyl group. This compound exhibits anti-inflammatory, analgesic, and antipyretic properties, making it useful in the treatment of various inflammatory conditions. Flufenamic acid is typically administered in its salt form and is known for its ability to inhibit cyclooxygenase enzymes, thereby reducing the synthesis of prostaglandins involved in inflammation and pain signaling. The substance is generally soluble in organic solvents but has limited solubility in water. Its pharmacological effects are attributed to its interaction with the arachidonic acid pathway, and it may also exhibit some degree of toxicity, necessitating careful dosage and monitoring during use. As with many NSAIDs, potential side effects can include gastrointestinal disturbances and cardiovascular risks.
Formula:C13H10FNO2
InChI:InChI=1/C13H10FNO2/c14-10-6-2-4-8-12(10)15-11-7-3-1-5-9(11)13(16)17/h1-8,15H,(H,16,17)
SMILES:c1ccc(c(c1)C(=O)O)Nc1ccccc1F
Synonyms:
  • 2-(2-Fluoroanilino)Benzoic Acid
  • Benzoic Acid, 2-[(2-Fluorophenyl)Amino]-
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