CAS 54-71-7
:Pilocarpine hydrochloride
Description:
Pilocarpine hydrochloride is a medication primarily used to treat conditions such as glaucoma and dry mouth (xerostomia). It is a synthetic alkaloid derived from the leaves of the Pilocarpus plant. As a hydrochloride salt, it is typically presented as a white to off-white crystalline powder that is soluble in water. Pilocarpine acts as a muscarinic agonist, stimulating the parasympathetic nervous system, which leads to increased salivation and lacrimation, as well as a reduction in intraocular pressure by facilitating aqueous humor outflow. The compound has a relatively low molecular weight and exhibits a moderate pKa, indicating its behavior as a weak base. Its pharmacological effects can lead to side effects such as sweating, increased salivation, and gastrointestinal disturbances. Due to its mechanism of action, pilocarpine is contraindicated in patients with certain conditions, such as asthma or other respiratory issues, where increased secretions could pose a risk. Overall, pilocarpine hydrochloride is a valuable therapeutic agent in specific medical contexts.
Formula:C11H17ClN2O2
InChI:InChI=1/C11H16N2O2/c1-3-10-8(6-15-11(10)14)4-9-5-12-7-13(9)2/h5,7-8,10H,3-4,6H2,1-2H3/t8-,10-/m0/s1
InChI key:InChIKey=RNAICSBVACLLGM-GNAZCLTHSA-N
SMILES:C([C@@H]1[C@H](CC)C(=O)OC1)C=2N(C)C=NC2.Cl
Synonyms:- (3S,4R)-3-ethyl-4-[(1-methyl-1H-imidazol-5-yl)methyl]dihydrofuran-2(3H)-one
- (3S,4R)-3-ethyl-4-[(1-methyl-1H-imidazol-5-yl)methyl]dihydrofuran-2(3H)-one hydrochloride (1:1)
- 2(3H)-Furanone, 3-ethyldihydro-4-[(1-methyl-1H-imidazol-5-yl)methyl]-, hydrochloride (1:1), (3S,4R)-
- 2(3H)-Furanone, 3-ethyldihydro-4-[(1-methyl-1H-imidazol-5-yl)methyl]-, monohydrochloride, (3S,4R)-
- 2(3H)-Furanone, 3-ethyldihydro-4-[(1-methyl-1H-imidazol-5-yl)methyl]-, monohydrochloride, (3S-cis)-
- Adsorbocarpine
- Almocarpine
- Isopto Carpine
- Nsc 5746
- Pilocar
- Pilocar SMP
- Pilocarpal
- Pilocarpina, Clorhidrato
- Pilocarpine Hcl
- Pilocarpine chloride
- Pilocarpine muriate
- Pilocarpine, chlorhydrate
- Pilocarpine, monohydrochloride
- Pilocarpinhydrochlorid
- Pilocarpinium chloride
- Pilocel
- Pilogel
- Pilovisc
- Salagen
- Sanpilo
- Vistacarpin N
- Pilocarpine hydrochloride
- Pilocarpine hydrochloride
- 3-ETHYL-4-[(1-METHYL-5-IMIDAZOLYL)METHYL]TETRAHYDROFURAN-2-ONE HYDROCHLORIDE
- 3-ethyldihydro-4-[(1-methyl-1h-imidazol-5-yl)methyl]-2(3h)-furanonmonohydr
- pilomiotin
- (3S-CIS)-3-ETHYLDIHYDRO-4-[(1-METHYL-1H-IMIDAZOL-5-YL)METHYL]-2(3H)-FURANONE HYDROCHLORIDE
- (3s-cis)-ochlorid
- pilocarpinemuriate
- 3-ethyldihydro-4-[(1-methyl-1H-imidazol-5-yl)methyl]-,monohydrochloride,(3S-cis)-2(3H)-Furanone
- mi-piloophthsol
- ALMOCARPINE HYDROCHLORIDE
- amisturap
- (3S,4R)-4,5-DIHYDRO-3-ETHYL-4-(1-METHYL-1H-IMIDAZOL-5-YLMETHYL)-2(3H)-FURANONE HYDROCHLORIDE
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Found 13 products.
Pilocarpine Hydrochloride
CAS:Formula:C11H16N2O2·HClPurity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:244.72PILOCARPINE HYDROCHLORIDE CRS
CAS:<p>PILOCARPINE HYDROCHLORIDE CRS</p>Formula:C11H16N2O2Color and Shape:Crystalline Powder. White. Colourless. Powder.Molecular weight:208.2569Pilocarpine Hydrochloride
CAS:<p>Other alkaloids,natural or reproduced by synthesis, and their salts, ethers,esters&other derivatives, nesoi</p>Formula:C11H16N2O2·ClHColor and Shape:Colorless Translucent White PowderMolecular weight:244.09786(3S,4R)-3-Ethyldihydro-4-[(1-methyl-1H-imidazol-5-yl)methyl]-2(3H)-furanone hydrochloride
CAS:Formula:C11H17ClN2O2Purity:99%Color and Shape:SolidMolecular weight:244.7179Pilocarpine Hydrochloride
CAS:<p>Pilocarpine Hydrochloride (NSC 5746 HCl) is an M3-type muscarinic acetylcholine receptor agonist. High-Quality, Low-Cost!</p>Formula:C11H16N2O2·HClPurity:98% - 99.89%Color and Shape:Oil Or Crystals SolidMolecular weight:244.72(+)-Pilocarpine hydrochloride
CAS:Formula:C11H16N2O2HClPurity:(anhydrous basis) EP 99.0 - 101.0 %, USP 98.0 - 102.0 %Color and Shape:Colourless, white or almost white crystalline powder or crystals, hygroscopicMolecular weight:244.72Pilocarpine hydrochloride
CAS:Natural alkaloidFormula:C11H16N2O2HClPurity:≥ 95.0 % (HPLC)Color and Shape:PowderMolecular weight:244.72Pilocarpine hydrochloride
CAS:<p>Pilocarpine hydrochloride is a cholinergic agonist, which is a derivative of the natural alkaloid pilocarpine. This compound is sourced from the leaves of the *Pilocarpus* species, particularly *Pilocarpus microphyllus* and *Pilocarpus jaborandi*. Its mode of action involves the stimulation of muscarinic receptors, primarily M3 receptors, which leads to increased secretion from exocrine glands and smooth muscle stimulation. In ophthalmology, pilocarpine hydrochloride is utilized to manage conditions such as glaucoma and ocular hypertension by inducing miosis to improve aqueous humor outflow and reduce intraocular pressure. Additionally, it is applied in the treatment of xerostomia (dry mouth), particularly in patients suffering from Sjögren's syndrome or those undergoing radiation therapy, by enhancing salivary gland secretion. Its clinical applications underscore its importance as a tool in both ocular and salivary gland dysfunction management.</p>Formula:C11H17ClN2O2Purity:Min. 95%Color and Shape:White PowderMolecular weight:244.72 g/molPilocarpine Hydrochloride
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Antiglaucoma agent; miotic; sialogogue.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Al-Badr, A.A., et al.: Anal. Profiles Drug Subs., 12, 385 (1983), Vivino, F.B., et al.: Arch. Intern. Med., 159, 174 (1999), Horiot, J.-C., et al.: Radiother. Oncol., 55, 233 (2000),<br></p>Formula:C11H16N2O2·ClHColor and Shape:White To Off-WhiteMolecular weight:244.72
![(3S,4R)-3-Ethyldihydro-4-[(1-methyl-1H-imidazol-5-yl)methyl]-2(3H)-furanone hydrochloride](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA003BD9.jpg&w=3840&q=75)
