CAS 5401-94-5

5-Nitroindazole

Description:

5-Nitroindazole is an organic compound characterized by its nitro group attached to the indazole structure, which is a bicyclic compound consisting of a fused benzene and pyrazole ring. It is typically a yellow to orange crystalline solid that is sparingly soluble in water but more soluble in organic solvents such as ethanol and dimethyl sulfoxide. The presence of the nitro group contributes to its chemical reactivity, making it a potential candidate for various chemical reactions, including reduction and nucleophilic substitution. 5-Nitroindazole has been studied for its biological activities, including antimicrobial and anti-inflammatory properties, and has been investigated in the context of pharmacological applications. Its molecular formula reflects the presence of nitrogen and oxygen atoms, which are integral to its functionality. As with many nitro compounds, care should be taken when handling 5-nitroindazole due to potential toxicity and environmental concerns. Proper safety protocols should be followed to mitigate any risks associated with its use in laboratory or industrial settings.

Formula: C₇H₅N₃O₂

InChI: InChI=1S/C7H5N3O2/c11-10(12)6-1-2-7-5(3-6)4-8-9-7/h1-4H,(H,8,9)

InChI key: InChIKey=WSGURAYTCUVDQL-UHFFFAOYSA-N

SMILES: N(=O)(=O)C=1C=C2C(=CC1)NN=C2

Synonyms:

• 1H-Indazole, 5-nitro-
• 5-Nitro Indazole
• 5-Nitro-1H-benzopyrazole
• 5-Nitro-1H-indazole
• 5-Nitroindazoles
• Indazole, 5-nitro-
• NSC 5032
• 5-Nitroindazole

5-Nitroindazole

CAS: 5401-94-5

Formula: C₇H₅N₃O₂

Purity: >98.0%(GC)

Color and Shape: White to Light yellow to Light orange powder to crystal

Molecular weight: 163.14

Ref: 3B-N0398

5-Nitro-1H-indazole, 98+%

CAS: 5401-94-5

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Formula: C₇H₅N₃O₂

Purity: 98+%

Color and Shape: White to cream or yellow to brown, Crystals or powder or crystalline powder and/or lumpy powder

Molecular weight: 163.14

Ref: 02-A13478

1H-Indazole, 5-nitro-

CAS: 5401-94-5

Formula: C₇H₅N₃O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 163.1335

Ref: IN-DA00I9N6

5-Nitro-1H-indazole

CAS: 5401-94-5

5-Nitro-1H-indazole

Formula: C₇H₅N₃O₂

Purity: 95%

Color and Shape: faint beige/brown solid

Molecular weight: 163.13g/mol

Ref: 54-OR9104

5-Nitroindazole

CAS: 5401-94-5

Formula: C₇H₅N₃O₂

Molecular weight: 163.14

Ref: 7W-GK9144

5-Nitro-1H-indazole

CAS: 5401-94-5

Formula: C₇H₅N₃O₂

Purity: 98%

Color and Shape: Solid, Beige powder

Molecular weight: 163.038

Ref: 10-F069163

5-Nitroindazole

CAS: 5401-94-5

5-Nitroindazole is a nitro compound that has been shown to have antineoplastic properties. It inhibits the division of cells by binding to DNA and preventing the formation of hydrogen bonds between purine bases, ultimately preventing DNA replication. 5-Nitroindazole has also been shown to inhibit mitochondrial membrane potential and induce apoptosis in human cancer cells. The antimicrobial activities of 5-nitroindazole are due to its chemical structure which allows for hydrogen bonding with cell walls or other components of bacteria. It is also possible that this compound exerts its action by reacting with nitric acid to form a hydroxyl radical, which can cause oxidative damage to bacterial membranes.

Formula: C₇H₅N₃O₂

Purity: Min. 95%

Molecular weight: 163.13 g/mol

Ref: 3D-FN36705