CAS 54012-92-9

8-Amino-1,2,3,4-tetrahydroquinoline

Description:

8-Amino-1,2,3,4-tetrahydroquinoline is a bicyclic organic compound characterized by its fused ring structure, which includes a quinoline moiety with an amino group at the 8-position. This compound typically appears as a colorless to pale yellow solid and is soluble in polar organic solvents. Its molecular structure contributes to its potential biological activity, making it of interest in medicinal chemistry, particularly for its possible applications in drug development. The presence of the amino group enhances its reactivity and ability to form hydrogen bonds, which can influence its interaction with biological targets. Additionally, 8-amino-1,2,3,4-tetrahydroquinoline may exhibit various pharmacological properties, including antimicrobial and anti-inflammatory activities. As with many nitrogen-containing heterocycles, it may also participate in various chemical reactions, such as alkylation and acylation, making it a versatile intermediate in organic synthesis. Safety and handling precautions should be observed, as with all chemical substances, due to potential toxicity and reactivity.

Formula: C₉H₁₂N₂

InChI: InChI=1S/C9H12N2/c10-8-5-1-3-7-4-2-6-11-9(7)8/h1,3,5,11H,2,4,6,10H2

InChI key: InChIKey=LILSBXJJIIFDGR-UHFFFAOYSA-N

SMILES: NC1=C2C(=CC=C1)CCCN2

Synonyms:

• 1,2,3,4-Tetrahydroquinolin-8-amine
• 8-Quinolinamine, 1,2,3,4-tetrahydro-
• 1,2,3,4-tetrahydroquinolin-8-amine
• Quinoline, 8-amino-1,2,3,4-tetrahydro-
• 1,2,3,4-Tetrahydro-8-quinolinamine
• 8-Amino-1,2,3,4-tetrahydroquinoline

8-Amino-1,2,3,4-tetrahydroquinoline

CAS: 54012-92-9

Formula: C₉H₁₂N₂

Purity: 95%

Molecular weight: 148.2050

Ref: IN-DA00D8U6

1,2,3,4-Tetrahydroquinolin-8-amine

CAS: 54012-92-9

1,2,3,4-Tetrahydroquinolin-8-amine

Purity: 95%

Molecular weight: 148.20g/mol

Ref: 54-OR95506

1,2,3,4-Tetrahydroquinolin-8-amine

CAS: 54012-92-9

Purity: 95%

Molecular weight: 148.2089996

Ref: 10-F721147

1,2,3,4-Tetrahydro-quinolin-8-ylamine

CAS: 54012-92-9

1,2,3,4-Tetrahydro-quinolin-8-ylamine is an experimental drug that acts as a tuberculosis prophylactic. It is the first quinoline derivative identified to have this effect and has shown promising results in vitro. This compound targets an enzyme that is involved in the synthesis of mycolic acid, which forms part of the cell wall of Mycobacterium tuberculosis. 1,2,3,4-Tetrahydro-quinolin-8-ylamine was found to be effective at inhibiting the growth of M. tuberculosis by binding to its protein and interfering with its function. The compound also inhibited the production of histamine from human cells in culture. Histochemical staining experiments showed that it can inhibit inflammatory responses in rat brain tissue.

Formula: C₉H₁₂N₂

Purity: Min. 95%

Molecular weight: 148.21 g/mol

Ref: 3D-ECA01292