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CAS 54063-32-0

:

Clobetasone

Description:
Clobetasone is a synthetic corticosteroid primarily used for its anti-inflammatory and immunosuppressive properties. It is characterized by its ability to reduce inflammation and alleviate symptoms associated with various skin conditions, such as eczema and dermatitis. Clobetasone functions by binding to glucocorticoid receptors, leading to the modulation of gene expression and subsequent reduction of inflammatory mediators. The substance is typically formulated as a topical cream or ointment, allowing for localized treatment with minimal systemic absorption. Its chemical structure includes a steroid backbone, which is essential for its biological activity. Clobetasone is generally well-tolerated, but like other corticosteroids, it may cause side effects such as skin thinning or irritation with prolonged use. It is classified under the category of medium-potency corticosteroids, making it suitable for treating moderate inflammatory skin conditions. As with any medication, it is important to use clobetasone under the guidance of a healthcare professional to ensure safety and efficacy.
Formula:C22H26ClFO4
InChI:InChI=1/C22H26ClFO4/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,24)17(26)10-20(16,3)22(12,28)18(27)11-23/h6-7,9,12,15-16,28H,4-5,8,10-11H2,1-3H3/t12-,15-,16-,19-,20-,21-,22-/m0/s1
InChI key:InChIKey=XXIFVOHLGBURIG-OZCCCYNHSA-N
SMILES:F[C@@]12[C@]([C@]3([C@](C)(CC1=O)[C@](C(CCl)=O)(O)[C@@H](C)C3)[H])(CCC=4[C@]2(C)C=CC(=O)C4)[H]
Synonyms:
  • (16Beta)-21-Chloro-9-Fluoro-17-Hydroxy-16-Methylpregna-1,4-Diene-3,11,20-Trione
  • (16β)-21-Chloro-9-fluoro-17-hydroxy-16-methylpregna-1,4-diene-3,11,20-trione
  • 21-Chlor-9-fluor-17-hydroxy-16beta-methyl-1,4-pregnadien-3,11,20-trion
  • 21-Chloro-11-dehydrobetamethasone
  • Clobetasona
  • Clobetasona [INN-Spanish]
  • Clobetasone [INN:BAN]
  • Clobetasonum
  • Clobetasonum [INN-Latin]
  • Pregna-1,4-diene-3,11,20-trione, 21-chloro-9-fluoro-17-hydroxy-16-methyl-, (16β)-
  • See more synonyms
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