CAS 54063-54-6

Reproterol

Description:

Reproterol is a synthetic compound classified as a selective beta-2 adrenergic agonist, primarily used in the treatment of respiratory conditions such as asthma and chronic obstructive pulmonary disease (COPD). It functions by stimulating beta-2 adrenergic receptors in the bronchial smooth muscle, leading to bronchodilation and improved airflow. Reproterol is characterized by its ability to provide rapid relief from bronchospasm, making it a valuable therapeutic agent in managing acute asthma attacks. The compound is typically administered via inhalation, allowing for direct delivery to the lungs and minimizing systemic side effects. Its pharmacological profile includes a relatively favorable safety margin, although potential side effects may include tremors, palpitations, and increased heart rate. As with other beta-2 agonists, caution is advised in patients with cardiovascular conditions. Reproterol's efficacy and safety have been evaluated in various clinical studies, contributing to its use in respiratory therapy. However, it is essential to follow medical guidelines and recommendations when using this medication.

Formula: C₁₈H₂₃N₅O₅

InChI: InChI=1S/C18H23N5O5/c1-21-16-15(17(27)22(2)18(21)28)23(10-20-16)5-3-4-19-9-14(26)11-6-12(24)8-13(25)7-11/h6-8,10,14,19,24-26H,3-5,9H2,1-2H3

InChI key: InChIKey=WVLAAKXASPCBGT-UHFFFAOYSA-N

SMILES: C(CCNCC(O)C1=CC(O)=CC(O)=C1)N2C3=C(N(C)C(=O)N(C)C3=O)N=C2

Synonyms:

• 1,2,3,6-Tetrahydro-1,3-dimethyl-7-(3-((beta,3,5-trihydroxyphenethyl)amino)propyl)-2,6-purindion
• 1H-Purine-2,6-dione, 7-[3-[[2-(3,5-dihydroxyphenyl)-2-hydroxyethyl]amino]propyl]-3,7-dihydro-1,3-dimethyl-
• 7-(3-((2-(3,5-Dihydroxyphenyl)-2-hydroxyethyl)amino)propyl)theophylline
• 7-(3-((beta,3,5-Trihydroxyphenethyl)amino)propyl)theophylline
• 7-[3-[[2-(3,5-Dihydroxyphenyl)-2-hydroxyethyl]amino]propyl]-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione
• Brn 0590567
• D 1959
• Reproterol [INN:BAN]
• Reproterolum
• Reproterolum [INN-Latin]
• Theophylline, 7-(3-((2-(3,5-dihydroxyphenyl)-2-hydroxyethyl)amino)propyl)-
• 5-26-14-00026 (Beilstein Handbook Reference)

Reproterol

CAS: 54063-54-6

Formula: C₁₈H₂₃N₅O₅

Molecular weight: 389.41

Ref: 4Z-R-167001

Reproterol-tetrahydroisoquinolone Derivative

Controlled Product

CAS: 54063-54-6

Applications Reproterol-tetrahydroisoquinolone Derivative is an impurity of Reproterol (R144650). Reproterol is an β2 adrenoceptor agonist for treating asthma. Reproterol is used as an bronchodilator.
References Sohda, T., et al.: Chem. Pharm. Bull., 30, 3580 (1982), Argenti, D., et al.: J. Clin. Pharmacol., 51, 400 (2001), Pearce, R., et al.: Drug Metab. Dispos., 34, 1035 (2006),

Formula: C₁₉H₂₃N₅O₅

Color and Shape: Neat

Molecular weight: 401.42

Ref: TR-R144654

Reproterol

Controlled Product

CAS: 54063-54-6

Applications Reproterol is an β2 adrenoceptor agonist for treating asthma. Reproterol is used as an bronchodilator.
References Sohda, T., et al.: Chem. Pharm. Bull., 30, 3580 (1982), Argenti, D., et al.: J. Clin. Pharmacol., 51, 400 (2001), Pearce, R., et al.: Drug Metab. Dispos., 34, 1035 (2006),

Formula: C₁₈H₂₃N₅O₅

Color and Shape: Brown

Molecular weight: 389.41

Ref: TR-R144650

Reproterol-d3 (Major)

Controlled Product

CAS: 54063-54-6

Applications Labelled Reproterol (R144650). Reproterol is an β2 adrenoceptor agonist for treating asthma. Reproterol is used as an bronchodilator.
References Sohda, T., et al.: Chem. Pharm. Bull., 30, 3580 (1982), Argenti, D., et al.: J. Clin. Pharmacol., 51, 400 (2001), Pearce, R., et al.: Drug Metab. Dispos., 34, 1035 (2006),

Formula: C₁₈H₂₀D₃N₅O₅

Color and Shape: Neat

Molecular weight: 392.42

Ref: TR-R144652