CAS 540769-28-6: Palosuran

Description: Palosuran, with the CAS number 540769-28-6, is a chemical compound that functions primarily as a selective antagonist of the endothelin receptor. It is characterized by its ability to inhibit the action of endothelin, a potent vasoconstrictor peptide involved in various physiological processes, including blood pressure regulation and vascular tone. Palosuran is notable for its potential therapeutic applications in treating conditions such as hypertension and heart failure, where modulation of the endothelin pathway may provide beneficial effects. The compound typically exhibits a favorable pharmacokinetic profile, allowing for effective oral bioavailability. Its chemical structure includes specific functional groups that contribute to its receptor selectivity and binding affinity. As with many pharmacological agents, the safety and efficacy of Palosuran are evaluated through clinical trials, and its use is subject to regulatory approval. Overall, Palosuran represents a significant interest in cardiovascular pharmacotherapy, reflecting ongoing research into endothelin receptor antagonism.

Formula: C₂₅H₃₀N₄O₂

InChI: InChI=1S/C25H30N4O2/c1-19-17-23(21-9-5-6-10-22(21)27-19)28-24(30)26-13-16-29-14-11-25(31,12-15-29)18-20-7-3-2-4-8-20/h2-10,17,31H,11-16,18H2,1H3,(H2,26,27,28,30)

InChI key: InChIKey=WYJCYXOCHXWTHG-UHFFFAOYSA-N

SMILES: O=C(NC1=CC(=NC=2C=CC=CC21)C)NCCN3CCC(O)(CC=4C=CC=CC4)CC3

Synonyms:

• ACT 058362
• 1-[2-(4-Benzyl-4-hydroxypiperidin-1-yl)ethyl]-3-(2-methylquinolin-4-yl)urea
• Urea, N-[2-[4-hydroxy-4-(phenylmethyl)-1-piperidinyl]ethyl]-N′-(2-methyl-4-quinolinyl)-
• Palosuran
• N-[2-[4-Hydroxy-4-(phenylmethyl)-1-piperidinyl]ethyl]-N′-(2-methyl-4-quinolinyl)urea

Palosuran

CAS: 540769-28-6

• Purity: ≥98%
• Molecular weight: 418.53g/mol

Palosuran

CAS: 540769-28-6

Palosuran (ACT-058362) (ACT-058362) is a new potent and specific antagonist of the human UT receptor.

• Formula: C₂₅H₃₀N₄O₂
• Purity: 98.46%
• Color and Shape: Solid
• Molecular weight: 418.53

Palosuran

CAS: 540769-28-6

Palosuran is a cyclic peptide polymerase chain that has been shown to inhibit the growth …

• Formula: C₂₅H₃₀N₄O₂
• Purity: Min. 95%
• Molecular weight: 418.53 g/mol