CAS 541-22-0

Decamethonium bromide

Description:

Decamethonium bromide is a synthetic quaternary ammonium compound primarily used as a neuromuscular blocking agent in clinical settings. It functions by competitively inhibiting the action of acetylcholine at the neuromuscular junction, leading to muscle paralysis, which is particularly useful during surgical procedures or in intensive care for facilitating intubation. The compound is characterized by its long-chain alkyl structure, which contributes to its potency and duration of action. Decamethonium bromide is typically administered intravenously and has a rapid onset of action, although its effects can be prolonged. It is important to monitor patients closely for potential side effects, including cardiovascular effects and respiratory depression, due to its mechanism of action. The compound is soluble in water, which aids in its administration, and it is generally stored in a cool, dry place to maintain stability. As with all neuromuscular blockers, its use requires careful consideration of dosage and patient-specific factors to ensure safety and efficacy.

Formula: C₁₆H₃₈N₂·2Br

InChI: InChI=1S/C16H38N2.2BrH/c1-17(2,3)15-13-11-9-7-8-10-12-14-16-18(4,5)6;;/h7-16H2,1-6H3;2*1H/q+2;;/p-2

InChI key: InChIKey=HLXQFVXURMXRPU-UHFFFAOYSA-L

SMILES: C([N+](C)(C)C)CCCCCCCCC[N+](C)(C)C.[Br-]

Synonyms:

• 1,10-Decanediaminium, N,N,N,N′,N′,N′-hexamethyl-, dibromide
• 1,10-Decanediaminium, N¹,N¹,N¹,N¹⁰,N¹⁰,N¹⁰-hexamethyl-, bromide (1:2)
• Ammonium, decamethylenebis[trimethyl- bromide]
• Ammonium, decamethylenebis[trimethyl-, dibromide
• C 10 (onium compound)
• Decacuran
• Decamethonium dibromide
• Decamethylene-1,10-bistrimethylammonium dibromide
• Decamethylenebis[trimethylammonium bromide]
• Decane-1,10-bis(trimethylammonium bromide)
• Syncurine

Decamethonium Bromide

CAS: 541-22-0

Formula: C₁₆H₃₈Br₂N₂

Purity: >98.0%(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 418.30

Ref: 3B-D1314

Decamethonium bromide

CAS: 541-22-0

Decamethonium bromide (Syncurine) is a neuromuscular blocker and nicotinic AChR partial agonist.

Formula: C₁₆H₃₈Br₂N₂

Purity: 99.90%

Color and Shape: Physical Description Crystals Derived From Methanol And Acetone (Ntp 1992)

Molecular weight: 418.29

Ref: TM-T0818

Decamethonium Bromide

CAS: 541-22-0

Formula: C₁₆H₃₈Br₂N₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 418.2943

Ref: IN-DA003P9B

Decamethonium bromide

CAS: 541-22-0

Decamethonium bromide

Purity: ≥98%

Molecular weight: 418.29g/mol

Ref: 54-BUP18870

Decamethonium bromide

CAS: 541-22-0

Formula: (CH₃)₃N(Br)(CH₂)₁₀N(Br)(CH₃)₃

Molecular weight: 418.29

Ref: 7W-GL2458

Decamethonium Bromide

CAS: 541-22-0

Decamethonium Bromide

Purity: 98%

Molecular weight: 418.30g/mol

Ref: 54-OR72793

DECAMETHONIUM BROMIDE

CAS: 541-22-0

Purity: 98%

Molecular weight: 418.302002

Ref: 10-F842545

Decamethonium Bromide

Controlled Product

CAS: 541-22-0

Applications Decamethonium Bromide is a nicotinic acetylcholine receptor partial agonist.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Formula: C₁₆H₃₈N₂₂• 2(Br

Color and Shape: Neat

Molecular weight: 258.49 + 2(79.90)

Ref: TR-D212453

Decamethonium bromide

CAS: 541-22-0

Decamethonium bromide is a potent and selective antagonist of nicotinic acetylcholine receptors. It is used in the treatment of autoimmune diseases, such as myasthenia gravis, Lambert-Eaton syndrome, and Guillain-Barre syndrome. Decamethonium bromide has been shown to inhibit the enzyme activity of acetylcholinesterase, which leads to an accumulation of acetylcholine at neuromuscular junctions. This causes muscle paralysis and increased bronchoconstriction in humans. In animal models, decamethonium bromide has been shown to be a potent inhibitor of receptor activity in the muscle tissue.

Formula: C₁₆H₃₈Br₂N₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 418.29 g/mol

Ref: 3D-FD61447