CAS 54127-31-0

2,3-Dichloro-5-(chloromethyl)pyridine

Description:

2,3-Dichloro-5-(chloromethyl)pyridine is a chlorinated pyridine derivative characterized by the presence of two chlorine atoms at the 2 and 3 positions and a chloromethyl group at the 5 position of the pyridine ring. This compound typically appears as a colorless to pale yellow liquid or solid, depending on its physical state at room temperature. It is known for its reactivity due to the presence of multiple halogen substituents, which can participate in various chemical reactions, including nucleophilic substitutions and electrophilic aromatic substitutions. The compound is soluble in organic solvents and may exhibit moderate toxicity, necessitating careful handling and appropriate safety measures during use. Its applications may include serving as an intermediate in the synthesis of pharmaceuticals, agrochemicals, or other organic compounds. As with many chlorinated compounds, it is important to consider environmental and health impacts, as well as regulatory guidelines regarding its use and disposal.

Formula: C₆H₄Cl₃N

InChI: InChI=1S/C6H4Cl3N/c7-2-4-1-5(8)6(9)10-3-4/h1,3H,2H2

InChI key: InChIKey=XJCSQVBPRZIYPY-UHFFFAOYSA-N

SMILES: C(Cl)C=1C=C(Cl)C(Cl)=NC1

Synonyms:

• Pyridine, 2,3-dichloro-5-(chloromethyl)-
• 2,3-Dichloro-5-(chloromethyl)pyridine
• 5-Chloromethyl-2,3-dichloropyridine

2,3-Dichloro-5-(chloromethyl)pyridine

CAS: 54127-31-0

Formula: C₆H₄Cl₃N

Purity: 95%

Color and Shape: Solid

Molecular weight: 196.4617

Ref: IN-DA00DHXP

5-(Chloromethyl)-2,3-dichloropyridine

CAS: 54127-31-0

5-(Chloromethyl)-2,3-dichloropyridine

Formula: C₆H₄Cl₃N

Purity: >95% (hnmr) (Typical Value in Batch COA)

Color and Shape: Low-Melting Solid

Molecular weight: 196.46g/mol

Ref: 54-OR43617

2,3-Dichloro-5-(chloromethyl)pyridine

CAS: 54127-31-0

Formula: C₆H₄Cl₃N

Purity: 95%

Molecular weight: 196.46

Ref: 10-F322606

2,3-Dichloro-5-(chloromethyl)pyridine

Controlled Product

CAS: 54127-31-0

Applications 2,3-Dichloro-5-(chloromethyl)pyridine is an intermediate used in the synthesis of 5-Chloro Imidacloprid (C366910), which is an impurity of Imidacloprid (I274990), a neonicotinoid; the active ingredient in certain neuro-active insecticides.
References Kagabu, S., et al.: J. Pesticide. Sci., 31, 150 (2006); Sung, N.D., et al.: Sung, N.D., et al.: Bull. Korean. Chem. Soc., 27, 1741 (2006); Tomizawa, M., et al.: J. Med. Chem., 52, 3735 (2009); Chem. and Eng. News 90: 10 (2012)

Formula: C₆H₄Cl₃N

Color and Shape: Neat

Molecular weight: 196.462

Ref: TR-D434610

5-(Chloromethyl)-2,3-dichloropyridine

CAS: 54127-31-0

5-(Chloromethyl)-2,3-dichloropyridine is a chlorinating agent that selectively converts alkenes to the corresponding dialkyl chlorides. It reacts with carbon monoxide to form a palladium catalyst and alkoxycarbonylation products. The yield of 5-(chloromethyl)-2,3-dichloropyridine is dependent on the type of substrate used and ranges from 60% to 100%.

Formula: C₆H₄Cl₃N

Purity: Min. 95%

Molecular weight: 196.46 g/mol

Ref: 3D-ECA12731