CAS 5413-85-4

5-Amino-4,6-dichloropyrimidine

Description:

5-Amino-4,6-dichloropyrimidine is a heterocyclic organic compound characterized by a pyrimidine ring substituted with amino and dichloro groups. Its molecular formula is C4H3Cl2N3, indicating the presence of chlorine atoms at the 4 and 6 positions of the pyrimidine ring, along with an amino group at the 5 position. This compound typically appears as a solid and is soluble in polar solvents, reflecting its polar functional groups. It is often utilized in the synthesis of pharmaceuticals and agrochemicals due to its ability to act as a building block in the formation of more complex molecules. The presence of the amino group allows for further chemical modifications, making it versatile in organic synthesis. Additionally, 5-amino-4,6-dichloropyrimidine may exhibit biological activity, which can be explored in various research applications. Safety data should be consulted for handling and usage, as with any chemical substance, to ensure proper precautions are taken.

Formula: C₄H₃Cl₂N₃

InChI: InChI=1S/C4H3Cl2N3/c5-3-2(7)4(6)9-1-8-3/h1H,7H2

InChI key: InChIKey=NIGDWBHWHVHOAD-UHFFFAOYSA-N

SMILES: NC=1C(Cl)=NC=NC1Cl

Synonyms:

• 4,6-Dichloro-5-aminopyrimidine
• 4,6-Dichloro-5-pyrimidinamine
• 4,6-Dichloropyrimidin-5-Amine
• 4,6-Dichloropyrimidin-5-Ylamine
• 5-Pyrimidinamine, 4,6-dichloro-
• NSC 7851
• Pyrimidine, 5-amino-4,6-dichloro-
• 5-Amino-4,6-dichloropyrimidine

5-Amino-4,6-dichloropyrimidine

CAS: 5413-85-4

Formula: C₄H₃Cl₂N₃

Purity: >98.0%(N)

Color and Shape: White to Light yellow to Light orange powder to crystal

Molecular weight: 163.99

Ref: 3B-A1395

5-Amino-4,6-dichloropyrimidine, 98+%

CAS: 5413-85-4

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₄H₃Cl₂N₃

Purity: 98+%

Color and Shape: White to cream, Crystals or powder or crystalline powder

Molecular weight: 163.99

Ref: 02-B24985

5-Amino-4,6-dichloropyrimidine

CAS: 5413-85-4

Formula: C₄H₃Cl₂N₃

Purity: 96%

Color and Shape: Solid

Molecular weight: 163.9927

Ref: IN-DA00346X

5-Amino-4,6-dichloropyrimidine

CAS: 5413-85-4

Formula: C₄H₃Cl₂N₃

Molecular weight: 164.00

Ref: 7W-GK5292

5-Amino-4,6-dichloropyrimidine

CAS: 5413-85-4

5-Amino-4,6-dichloropyrimidine

Formula: C₄H₃Cl₂N₃

Purity: 98%

Color and Shape: pale brown solid

Molecular weight: 163.99g/mol

Ref: 54-OR8769

5-Amino-4,6-dichloropyrimidine

Controlled Product

CAS: 5413-85-4

Applications An intermediate in the production of many biological inhibitors.
References Lambertucci, C., et al.: Bioorg. Med. Chem., 17, 2812 (2009), Lebsack, A., et al.: Bioorg. Med. Chem. Lett., 19, 40 (2009), Griffith, D., et al.: J. Med. Chem., 52, 234 (2009),

Formula: C₄H₃Cl₂N₃

Color and Shape: Neat

Molecular weight: 163.99

Ref: TR-A604725

5-Amino-4,6-dichloropyrimidine

CAS: 5413-85-4

5-Amino-4,6-dichloropyrimidine is a fluorescent probe that can be used in the detection of nucleophiles. It has been shown to inhibit the growth of cells infected with herpes simplex virus and hl-60 cells. This compound has also been shown to have nicotinic acetylcholine receptor activity and can be used as an analog for purines. The nitrogen atoms in this molecule are responsible for its anti-cancer properties. 5-Amino-4,6-dichloropyrimidine binds to epidermal growth factor (EGF) and blocks its binding site on the cell surface, reducing cancer cell proliferation. Benzyl groups on either end of this molecule act as a protective group against acid hydrolysis, making it stable in acidic environments such as stomach acid. This drug also contains chlorine atoms that make it easy to synthesize and purify by reacting with trifluoroacetic acid.

Formula: C₄H₃Cl₂N₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 163.99 g/mol

Ref: 3D-FA11123

5-Amino-4,6-dichloropyrimidine

CAS: 5413-85-4

Formula: C₄H₃Cl₂N₃

Purity: 96%

Color and Shape: Solid

Molecular weight: 163.99

Ref: 10-F024634