CAS 54143-55-4

Flecainide

Description:

Flecainide is a class IC antiarrhythmic medication primarily used to treat certain types of serious irregular heartbeats, such as atrial fibrillation and ventricular tachycardia. It functions by blocking sodium channels in cardiac cells, which helps to stabilize the cardiac membrane and reduce excitability. Flecainide is typically administered orally and is known for its high bioavailability. The substance is characterized by its relatively low solubility in water, which can affect its absorption and distribution in the body. Its chemical formula is C17H20F6N2O3, and it has a molecular weight that reflects its complex structure, which includes a fluorinated aromatic ring. Flecainide is also associated with potential side effects, including proarrhythmia, particularly in patients with structural heart disease. Therefore, careful monitoring is essential during treatment. Overall, flecainide is a potent antiarrhythmic agent that requires a thorough understanding of its pharmacokinetics and pharmacodynamics for safe and effective use in clinical practice.

Formula: C₁₇H₂₀F₆N₂O₃

InChI: InChI=1S/C17H20F6N2O3/c18-16(19,20)9-27-12-4-5-14(28-10-17(21,22)23)13(7-12)15(26)25-8-11-3-1-2-6-24-11/h4-5,7,11,24H,1-3,6,8-10H2,(H,25,26)

InChI key: InChIKey=DJBNUMBKLMJRSA-UHFFFAOYSA-N

SMILES: C(NCC1CCCCN1)(=O)C2=C(OCC(F)(F)F)C=CC(OCC(F)(F)F)=C2

Synonyms:

• Benzamide, N-(2-piperidinylmethyl)-2,5-bis(2,2,2-trifluoroethoxy)-
• Flecaine
• Flecainide
• N-(2-Piperidinylmethyl)-2,5-bis(2,2,2-trifluoroethoxy)benzamide

Flecainide

CAS: 54143-55-4

Formula: C₁₇H₂₀F₆N₂O₃

Purity: 95%

Color and Shape: Solid

Molecular weight: 414.3427

Ref: IN-DA003SF2

Flecainide

CAS: 54143-55-4

Flecainide

Purity: 98%

Molecular weight: 414.34g/mol

Ref: 54-PC109156

rac-Flecainide

CAS: 54143-55-4

Formula: C₁₇H₂₀F₆N₂O₃

Molecular weight: 414.35

Ref: 4Z-F-381

Flecainide

CAS: 54143-55-4

Flecainide is an orally administered antiarrhythmic agent acting as a sodium channel blocker and IKr inhibitor,PSVT.

Formula: C₁₇H₂₀F₆N₂O₃

Purity: 99.896%

Color and Shape: Solid

Molecular weight: 414.34

Ref: TM-T21391

Flecainide Impurity 7

CAS: 54143-55-4

Formula: C₁₂H₈F₆O₆

Molecular weight: 362.18

Ref: 4Z-F-3815

Flecainide

CAS: 54143-55-4

Applications Flecainide is an antiarrhythmic (class IC).
References Hodess, A.B., et al.: J. Cardiovasc. Pharmacol., 1, 427 (1979), Somani, P., et al.: Clin. Pharmacol. Ther., 27, 464 (1980), Alessi-Severini, S., et al.: Anal. Profiles Drug Subs. Excip., 21, 169 (1992)

Formula: C₁₇H₂₀F₆N₂O₃

Color and Shape: Neat

Molecular weight: 414.34

Ref: TR-F390000

rac-Flecainide

CAS: 54143-55-4

Rac-Flecainide is an antiarrhythmic drug that belongs to the class of nonsteroidal anti-inflammatory drugs. It is used for the treatment of ventricular arrhythmias, atrial arrhythmias, and cardiac conduction disturbances. Rac-Flecainide has been shown to be effective in treating tachycardia, especially when associated with structural heart disease or other cardiac disease. Rac-Flecainide is a sodium salt that can interact with other pharmacological agents such as nonsteroidal anti-inflammatory drugs, which may increase the risk of adverse effects.

Formula: C₁₇H₂₀F₆N₂O₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 414.34 g/mol

Ref: 3D-FF27520

Flecainide

CAS: 54143-55-4

Purity: 98%

Molecular weight: 414.3479919

Ref: 10-F791093