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CAS 54143-57-6

:

Metoclopramide monohydrochloride monohydrate

Description:
Metoclopramide monohydrochloride monohydrate is a pharmaceutical compound primarily used as an antiemetic and gastroprokinetic agent. It is a white to off-white crystalline powder that is soluble in water, which facilitates its use in various formulations, including oral tablets and injectable solutions. The substance acts primarily by blocking dopamine receptors in the central nervous system, thereby reducing nausea and vomiting, and enhancing gastrointestinal motility. Its chemical structure includes a substituted benzamide, which contributes to its pharmacological properties. The monohydrochloride form indicates the presence of one hydrochloride molecule per metoclopramide molecule, while the monohydrate designation signifies the inclusion of one water molecule in the crystal structure. This compound is typically administered in controlled doses due to potential side effects, including drowsiness and extrapyramidal symptoms. As with any medication, it is essential to consider contraindications and interactions with other drugs when prescribing metoclopramide monohydrochloride monohydrate.
Formula:C14H22ClN3O2·ClH·H2O
InChI:InChI=1S/C14H22ClN3O2.ClH.H2O/c1-4-18(5-2)7-6-17-14(19)10-8-11(15)12(16)9-13(10)20-3;;/h8-9H,4-7,16H2,1-3H3,(H,17,19);1H;1H2
InChI key:InChIKey=KJBLQGHJOCAOJP-UHFFFAOYSA-N
SMILES:C(NCCN(CC)CC)(=O)C1=C(OC)C=C(N)C(Cl)=C1.Cl.O
Synonyms:
  • 4-Amino-5-chloro-N-(2-(diethylamino)ethyl)-2-methoxybenzamide monohydrochloride
  • 4-Amino-5-chloro-N-(2-(diethylamino)ethyl)-o-anisamide hydrochloride
  • 4-Amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide hydrochloride (1:1)
  • 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide hydrochloride
  • 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide hydrochloride hydrate
  • 4-amino-5-chloro-N-[2-(diéthylamino)éthyl]-2-méthoxybenzamide chlorhydrate
  • 54143-57-6
  • Benzamide, 4-amino-5-chloro-N-(2-(diethylamino)ethyl)-2-methoxy-, monohydrochloride (9CI)
  • Benzamide, 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxy-, hydrochloride, hydrate (1:1:1)
  • Benzamide, 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxy-, monohydrochloride, monohydrate
  • See more synonyms
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