CAS 541550-19-0

Apilimod

Description:

Apilimod, with the CAS number 541550-19-0, is a small molecule that functions primarily as a selective inhibitor of the enzyme phosphoinositide 3-kinase (PI3K). It is known for its immunomodulatory properties, particularly in the context of autoimmune diseases and certain types of cancer. Apilimod has been studied for its ability to inhibit the production of pro-inflammatory cytokines, thereby modulating immune responses. The compound is characterized by its specific binding affinity to the target enzyme, which plays a crucial role in various cellular processes, including cell growth, proliferation, and survival. In terms of its chemical structure, Apilimod contains a pyrimidine core, which is essential for its biological activity. The substance is typically administered in a pharmaceutical context, and its efficacy and safety profiles are evaluated through clinical trials. Overall, Apilimod represents a promising therapeutic agent in the field of immunology and oncology, with ongoing research aimed at elucidating its full potential and mechanisms of action.

Formula: C₂₃H₂₆N₆O₂

InChI: InChI=1S/C23H26N6O2/c1-18-5-4-6-19(15-18)17-25-28-21-16-22(29-10-13-30-14-11-29)27-23(26-21)31-12-8-20-7-2-3-9-24-20/h2-7,9,15-17H,8,10-14H2,1H3,(H,26,27,28)

InChI key: InChIKey=HSKAZIJJKRAJAV-UHFFFAOYSA-N

SMILES: N(N=CC1=CC(C)=CC=C1)C2=CC(=NC(OCCC3=CC=CC=N3)=N2)N4CCOCC4

Synonyms:

• Apilimod
• Benzaldehyde, 3-methyl-, [6-(4-morpholinyl)-2-[2-(2-pyridinyl)ethoxy]-4-pyrimidinyl]hydrazone
• Benzaldehyde,3-methyl-, [6-(4-morpholinyl)-2-[2-(2-pyridinyl)ethoxy]-4-pyrimidinyl]hydrazone(9CI)
• Sta 5326
• LAM 002
• Benzaldehyde, 3-methyl-, 2-[6-(4-morpholinyl)-2-[2-(2-pyridinyl)ethoxy]-4-pyrimidinyl]hydrazone

APILIMOD

CAS: 541550-19-0

Formula: C₂₃H₂₆N₆O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 418.4915

Ref: IN-DA00DDDF

Apilimod

CAS: 541550-19-0

Apilimod

Purity: ≥98%

Molecular weight: 418.49g/mol

Ref: 54-BUP13447

4-(6-(2-(3-Methylbenzylidene)Hydrazinyl)-2-(2-(Pyridin-2-Yl)Ethoxy)Pyrimidin-4-Yl)Morpholine

CAS: 541550-19-0

4-(6-(2-(3-Methylbenzylidene)Hydrazinyl)-2-(2-(Pyridin-2-Yl)Ethoxy)Pyrimidin-4-Yl)Morpholine

Purity: 98%

Molecular weight: 418.49g/mol

Ref: 54-OR1023088

Apilimod

CAS: 541550-19-0

Formula: C₂₃H₂₆N₆O₂

Molecular weight: 418.50

Ref: 4Z-K-031048

Apilimod

CAS: 541550-19-0

Apilimod (STA 5326) inhibits the production of IL-12 and IL-23 and reduces dendritic cell infiltration in psoriasis.

Formula: C₂₃H₂₆N₆O₂

Purity: 99.38% - 99.89%

Color and Shape: Solid

Molecular weight: 418.49

Ref: TM-T2018

Apilimod

CAS: 541550-19-0

Apilimod is a small molecule that inhibits the activity of the signal transduction pathways involved in the activation of lymphocytes and macrophages. It has been shown to inhibit viral replication and neuronal death, as well as to induce significant cytotoxicity. Apilimod also suppresses inflammatory bowel disease by inhibiting TLR-mediated signaling pathways. Apilimod is an inhibitor of toll-like receptor (TLR) signaling for IBDs, including ulcerative colitis and Crohn's disease.

Purity: Min. 95%

Ref: 3D-BA177430