CAS 5417-84-5

6-ethylmercaptopurine

Description:

6-Ethylmercaptopurine, with the CAS number 5417-84-5, is a chemical compound that belongs to the class of purine derivatives. It is characterized by the presence of a mercapto group (-SH) and an ethyl group attached to the purine structure, which contributes to its unique properties. This compound is typically a white to off-white solid and is soluble in polar solvents, such as water and alcohols, due to its functional groups. 6-Ethylmercaptopurine is primarily studied for its potential pharmacological applications, particularly in the field of oncology, as it may exhibit antitumor activity. Its mechanism of action is thought to involve the inhibition of purine metabolism, which can disrupt nucleic acid synthesis in rapidly dividing cells. As with many chemical substances, handling 6-ethylmercaptopurine requires caution due to its potential toxicity and the need for proper safety measures in laboratory settings. Overall, this compound represents an interesting area of research in medicinal chemistry and drug development.

Formula: C₇H₈N₄S

InChI: InChI=1/C7H8N4S/c1-2-12-7-5-6(9-3-8-5)10-4-11-7/h3-5H,2H2,1H3

InChI key: InChIKey=XTJLAIOQORFEOI-UHFFFAOYSA-N

SMILES: S(CC)C1=C2C(N=CN2)=NC=N1

Synonyms:

• 1H-Purine, 6-(ethylthio)-
• 6-(Ethylthio)-9H-purine
• 6-(Ethylthio)purine
• 6-(ethylsulfanyl)-5H-purine
• 6-(ethylsulfanyl)-7H-purine
• 6-Ethyl MP
• 6-Ethylthiopurine
• 9H-Purine, 6-(ethylthio)-
• Ai3-50227
• Nsc 11588
• Purine, 6-(ethylthio)-
• Qa 69
• 6-Ethylmercaptopurine
• 6-Ethylmercaptopurine
• 6-(ethylthio)-purin
• 6-(ethylthio)-7H-purine

6-(Ethylthio)-7H-purine

CAS: 5417-84-5

Formula: C₇H₈N₄S

Molecular weight: 180.2302

Ref: IN-DA00DAYY

6-Ethylmercaptopurine

CAS: 5417-84-5

Formula: C₇H₈N₄S

Purity: ≥ 98.0% (dried basis)

Color and Shape: Off-white to pale yellow powder

Molecular weight: 180.23

Ref: 7W-GL5586

6-Ethylmercaptopurine

CAS: 5417-84-5

6-Ethylmercaptopurine is a purine analogue that inhibits the synthesis of DNA. It is used as an inhibitor of protein synthesis and in the treatment of inflammatory bowel disease. 6-Ethylmercaptopurine has been shown to inhibit the activity of ATPase, which may be responsible for its ability to suppress the proliferation of cells. This drug can also act as an analog to adenosine, which can be used to determine ATP levels in a cell or tissue sample by measuring the amount of p-nitrophenyl phosphate produced. 6-Ethylmercaptopurine has been shown to block phosphatase activity, which may lead to inflammation in some cases.
6-Ethylmercaptopurine has a molecular weight of 194.2 g/mol and an optimum pH of 4.5

Formula: C₇H₈N₄S

Purity: Min. 95%

Color and Shape: Off-White Powder

Molecular weight: 180.23 g/mol

Ref: 3D-FE08008