CAS 5418-93-9

2-Amino-5-chlorobenzimidazole

Description:

2-Amino-5-chlorobenzimidazole is an organic compound characterized by its benzimidazole core, which consists of a fused benzene and imidazole ring. The presence of an amino group (-NH2) at the 2-position and a chlorine atom at the 5-position of the benzimidazole structure contributes to its unique chemical properties. This compound is typically a solid at room temperature and is soluble in polar solvents, such as water and alcohols, due to the presence of the amino group, which can engage in hydrogen bonding. It exhibits basic properties due to the amino group, allowing it to participate in various chemical reactions, including nucleophilic substitutions and coupling reactions. 2-Amino-5-chlorobenzimidazole is of interest in pharmaceutical research and may serve as a precursor or intermediate in the synthesis of biologically active compounds. Its reactivity and functional groups make it a valuable compound in organic synthesis and medicinal chemistry. Safety data should be consulted for handling and usage, as with any chemical substance.

Formula: C₇H₆ClN₃

InChI: InChI=1S/C7H6ClN3/c8-4-1-2-5-6(3-4)11-7(9)10-5/h1-3H,(H3,9,10,11)

InChI key: InChIKey=PDOCNPCPPLPXRV-UHFFFAOYSA-N

SMILES: NC=1NC=2C(N1)=CC(Cl)=CC2

Synonyms:

• 1H-Benzimidazol-2-amine, 5-chloro-
• 1H-benzimidazol-2-amine, 6-chloro-
• 2-Amino-5-chloro-1H-benzimidazole
• 2-Amino-5-chlorobenzimidazole
• 2-Amino-6-chlorobenzimidazole
• 5-Chloro-1H-benzimidazol-2-amine
• 5-Chloro-2-aminobenzimidazole
• 5-Chloro-2-benzimidazolamine
• 5-Chlorobenzoimidazol-2-ylamine
• Benzimidazole, 2-amino-5(or 6)-chloro-
• Benzimidazole, 2-amino-5-chloro-
• NSC 10545
• 6-Chloro-1H-benzimidazol-2-amine

6-Chloro-1H-benzo[d]imidazol-2-amine

CAS: 5418-93-9

Formula: C₇H₆ClN₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 167.5956

Ref: IN-DA00D9X3

6-Chloro-1H-benzimidazol-2-amine

CAS: 5418-93-9

6-Chloro-1H-benzimidazol-2-amine

Purity: 95%

Molecular weight: 167.60g/mol

Ref: 54-OR46629

5-Chloro-1H-benzoimidazol-2-ylamine

CAS: 5418-93-9

Formula: C₇H₆ClN₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 167.6

Ref: 10-F015424

6-Chloro-1H-benzimidazol-2-amine

CAS: 5418-93-9

Aminoguanidine is a drug that inhibits the activity of the enzyme guanidinoacetate methyltransferase (GAMT). It is used to treat some types of cancer, such as bladder cancer. Aminoguanidine has been shown to inhibit tumour growth and induce apoptosis in animal models. It has also been reported to be effective in a number of other cancers, including breast cancer, prostate cancer and colon cancer. Aminoguanidine binds with high affinity to protein targets, including x-ray crystallography, magnetic resonance imaging and devices. The binding site on the ligand is highly conserved among different proteins, which may explain the broad spectrum of its activity. Aminoguanidine is dose-dependent and can be administered either stepwise or as one large dose.

Formula: C₇H₆ClN₃

Purity: Min. 95%

Molecular weight: 167.6 g/mol

Ref: 3D-FAA41893