CAS 54182-58-0

Sucralfate

Description:

Sucralfate is a medication primarily used to treat and prevent ulcers in the gastrointestinal tract. It is a complex of sucrose sulfate and aluminum hydroxide, which forms a protective barrier over ulcers and erosions in the stomach and duodenum, promoting healing. Sucralfate is characterized by its ability to adhere to damaged mucosal tissue, creating a physical barrier that protects against gastric acid and digestive enzymes. This action helps to reduce irritation and allows for the natural healing process to occur. The substance is typically administered orally and is not absorbed significantly into the bloodstream, which minimizes systemic side effects. Sucralfate is generally well-tolerated, but it may interact with other medications by inhibiting their absorption, so it is important to space its administration from other drugs. Common side effects can include constipation, dry mouth, and gastrointestinal discomfort. Overall, sucralfate is a valuable therapeutic agent in the management of peptic ulcer disease and related conditions.

Formula: C₁₂H₅₄Al₁₆O₇₅S₈

InChI: InChI=1S/C12H22O35S8.16Al.40H2O/c13-48(14,15)37-1-4-6(43-51(22,23)24)8(45-53(28,29)30)9(46-54(31,32)33)11(40-4)42-12(3-39-50(19,20)21)10(47-55(34,35)36)7(44-52(25,26)27)5(41-12)2-38-49(16,17)18;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;/h4-11H,1-3H2,(H,13,14,15)(H,16,17,18)(H,19,20,21)(H,22,23,24)(H,25,26,27)(H,28,29,30)(H,31,32,33)(H,34,35,36);;;;;;;;;;;;;;;;;40*1H2/q;16*+3;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;/p-48/t4-,5-,6-,7-,8+,9-,10+,11-,12+;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;/m1......................................................../s1

InChI key: InChIKey=DTULOKYBGCTCFP-QRLOXDDHSA-A

SMILES: O([C@@]1(COS([O-][Al+3]2([OH-])[OH-][Al+3]([OH-])([OH-])[OH-]2)(=O)=O)[C@@H](OS([O-][Al+3]3([OH-])[OH-][Al+3]([OH-])([OH-])[OH-]3)(=O)=O)[C@H](OS([O-][Al+3]4([OH-])[OH-][Al+3]([OH-])([OH-])[OH-]4)(=O)=O)[C@@H](COS([O-][Al+3]5([OH-])[OH-][Al+3]([OH-])([OH-])[OH-]5)(=O)=O)O1)[C@@H]6[C@H](OS([O-][Al+3]7([OH-])[OH-][Al+3]([OH-])([OH-])[OH-]7)(=O)=O)[C@@H](OS([O-][Al+3]8([OH-])[OH-][Al+3]([OH-])([OH-])[OH-]8)(=O)=O)[C@H](OS([O-][Al+3]9([OH-])[OH-][Al+3]([OH-])([OH-])[OH-]9)(=O)=O)[C@@H](COS([O-][Al+3]%10([OH-])[OH-][Al+3]([OH-])([OH-])[OH-]%10)(=O)=O)O6

Synonyms:

• Aluminium, hexadeca-μ-hydroxytetracosahydroxy[μ8-[1,3,4,6-tetra-O-sulfo-β-D-fructofuranosyl α-D-glucopyranoside tetrakis(hydrogen sulfato)(8-)]]hexadeca-
• Aluminum, hexadeca-μ-hydroxytetracosahydroxy[μ₈-[[1,3,4,6-tetra-O-sulfo-β-<span class="text-smallcaps">D</smallcap>-fructofuranosyl α-<smallcap>D</span>-glucopyranoside tetrakis(sulfato-κO′)](8-)]]hexadeca-
• Antepsin
• Carafate
• Citogel
• Hexadeca-μ-hydroxytetracosahydroxy[μ₈-[[1,3,4,6-tetra-O-sulfo-β-<span class="text-smallcaps">D</smallcap>-fructofuranosyl α-<smallcap>D</span>-glucopyranoside tetrakis(sulfato-κO′)](8-)]]hexadecaaluminum
• Hexagastron
• Keal
• Succosa
• Sucralafate
• Sucralfat
• Sucralfate
• Sucralfato
• Sucralfin
• Sucrate
• Sugast
• Sulcrate
• Ulcar
• Ulcerlmin
• Ulcermin
• Ulcogant
• Urbal
• Venter
• Hexadeca-μ-hydroxytetracosahydroxy[μ8-[[1,3,4,6-tetra-O-sulfo-β-D-fructofuranosyl α-D-glucopyranoside tetrakis(sulfato-κO′)](8-)]]hexadecaaluminum

SUCRALFATE CRS

CAS: 54182-58-0

SUCRALFATE CRS

Ref: 41-Y0001324

Sucralfate

CAS: 54182-58-0

Sucralfate (Sucrose octasulfate–aluminum complex) is a cytoprotective agent, an oral gastrointestinal medication primarily indicated for the treatment of active

Formula: C₁₂H₅₄Al₁₆O₇₅S₈

Purity: 98%

Color and Shape: White Amorphous Powder

Molecular weight: 2086.75

Ref: TM-T1338

Aluminum,hexadeca-m-hydroxytetracosahydroxy[m8-[[1,3,4,6-tetra-O-sulfo-b-D-fructofuranosyl a-D-glucopyranoside tetrakis(sulfato-kO')](8-)]]hexadeca-

CAS: 54182-58-0

Formula: C₁₂H₅₄Al₁₆O₇₅S₈

Color and Shape: Solid

Molecular weight: 2086.7368

Ref: IN-DA01CCK2

Sucralfate, USP grade

CAS: 54182-58-0

Formula: C₁₂H₅₄Al₁₆O₇₅S₈

Color and Shape: White to off-white powder

Molecular weight: 2086.74

Ref: 7W-GC9742

Sucralfate

CAS: 54182-58-0

Formula: C₁₂H₃₀Al₈O₅₁S₈·nAlOH

Molecular weight: 1462.65 n*78.00

Ref: 4Z-S-155001

Sucrose octasulfate-aluminum complex

CAS: 54182-58-0

Formula: C₁₂H₅₄Al₁₆O₇₅S₈

Color and Shape: White to off-white powder

Molecular weight: 2086.74

Ref: 7W-GC0234

Sucralfate

CAS: 54182-58-0

Applications An inhibitor of peptic hydrolysis and stomach acidity. Used as an anti-ulcerative.
References Mayberr, J.F., et al.: Brit. J. Clin. Pract., 32, 291 (1978); Brogden, R.N., et al.: Drugs, 27, 194 (1984);

Formula: C₁₂H₅₄Al₁₆O₇₅S₈

Color and Shape: Neat

Molecular weight: 2086.74

Ref: TR-S692350

Sucralfate

CAS: 54182-58-0

Sucralfate is a drug that is used to treat and prevent injury-related inflammation by forming a protective barrier on the lining of the stomach and duodenum. Sucralfate has been shown to be effective in the treatment of infectious diseases, such as viral or bacterial infections, and also for radiation enteritis and ulcerative colitis. Sucralfate may interfere with the absorption of other drugs, such as acyclic nucleoside phosphonates, which are used to treat HIV/AIDS. This drug has also been shown to have anti-inflammatory properties through inhibition of prostaglandin synthesis. Sucralfate has been shown to have anti-inflammatory properties through inhibition of prostaglandin synthesis.

Formula: C₁₂H₅₄Al₁₆O₇₅S₈

Color and Shape: White Off-White Powder

Molecular weight: 2,086.74 g/mol

Ref: 3D-OS05733

Sucrose Octasulphate Aluminium Salt (Sucralfate) extrapure, 30-36%

CAS: 54182-58-0

Formula: C₁₂H₅₄Al₁₆O₇₅S₈

Color and Shape: White to off-white, Powder, Clear

Molecular weight: 2086.74

Ref: SR-47973

Sucralfate

CAS: 54182-58-0

Formula: C₁₂H₅₄Al₁₆O₇₅S₈

Molecular weight: 2086.7

Ref: ST-EA-CP-S46000