CAS 54197-66-9

6-Hydroxy-3,4-dihydro-2(1H)-quinolinone

Description:

6-Hydroxy-3,4-dihydro-2(1H)-quinolinone, with the CAS number 54197-66-9, is a chemical compound that belongs to the class of quinolinones, which are bicyclic compounds containing a quinoline ring fused with a lactam. This substance is characterized by the presence of a hydroxyl group at the 6-position and a saturated dihydro structure, which contributes to its unique chemical properties. It typically exhibits moderate solubility in polar solvents due to the hydroxyl group, while its aromatic nature may allow for interactions with various biological targets. The compound may possess biological activity, making it of interest in medicinal chemistry and pharmacology. Its structural features suggest potential applications in drug development, particularly in the synthesis of derivatives that could enhance therapeutic efficacy. Additionally, the compound's stability and reactivity can be influenced by the presence of functional groups, making it a subject of study in organic synthesis and material science.

Formula: C₉H₉NO₂

InChI: InChI=1S/C9H9NO2/c11-7-2-3-8-6(5-7)1-4-9(12)10-8/h2-3,5,11H,1,4H2,(H,10,12)

InChI key: InChIKey=HOSGXJWQVBHGLT-UHFFFAOYSA-N

SMILES: OC=1C=C2C(NC(=O)CC2)=CC1

Synonyms:

• 2(1H)-Quinolinone, 3,4-dihydro-6-hydroxy-
• 2-Oxo-1,2,3,4-tetrahydroquinolin-6-ol
• 3,4-Dihydro-6-hydroxy-2-[1H]-quinolinone
• 3,4-Dihydro-6-hydroxycarbostyril
• 3,4-Dihydroquinoline-2,6-diol
• 6-Hydroxy-1,2,3,4-tetrahydro-2-quinolinone
• 6-Hydroxy-2(1H)-3,4-Dihydroquinolinone
• 6-Hydroxy-2-Oxo-1,2,3,4-Tetrahydro Quinoline
• 6-Hydroxy-2-Oxo-1,2,3,4-Tetrahydroquinoline (6-Hq)
• 6-Hydroxy-2-oxo-1,2,3,4-tetrahydroquinoline
• 6-Hydroxy-3,4-dihydro carbostilyl
• 6-Hydroxy-3,4-dihydro-1H-quinolin-2-one
• 6-Hydroxy-3,4-dihydrocarbostyril
• 6-Hydroxy-3,4-dihydroquinazolone
• 6-Hydroxyl-3.4-dihydro-2-(1H)-quinolinone
• 6-hydroxy-3,4-dihydro-2(1H)-quinolinone
• 6-hydroxy-3,4-dihydroquinolin-2(1H)-one
• Carbostyril, 3,4-dihydro-6-hydroxy-

3,4-Dihydro-6-hydroxy-2(1H)-quinolinone

CAS: 54197-66-9

Formula: C₉H₉NO₂

Purity: >98.0%(HPLC)(N)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 163.18

Ref: 3B-D3448

Cilostazol Related Compound A (6-hydroxy-3,4-dihydro-1H-quinolin-2-one)

CAS: 54197-66-9

Lactams not elsewhere specified or included

Formula: C₉H₉NO₂

Color and Shape: Yellow White Powder

Molecular weight: 163.17

Ref: 45-1134164

3,4-Dihydro-6-hydroxy-2(1H)-quinolinone

CAS: 54197-66-9

Formula: C₉H₉NO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 163.1733

Ref: IN-DA003N8B

6-Hydroxy-2-oxo-1,2,3,4-tetrahydroquinoline

CAS: 54197-66-9

Formula: C₉H₉NO₂

Purity: ≥ 98.0%

Color and Shape: White to off-white crystalline powder

Molecular weight: 163.17

Ref: 7W-GK0779

6-Hydroxy-3,4-dihydro-1H-quinolin-2-one

Controlled Product

CAS: 54197-66-9

Formula: C₉H₉NO₂

Color and Shape: Neat

Molecular weight: 163.17

Ref: 86-MM0796.02

3,4-Dihydro-6-hydroxyquinolin-2(1H)-one

CAS: 54197-66-9

3,4-Dihydro-6-hydroxyquinolin-2(1H)-one

Purity: 98%

Molecular weight: 163.17g/mol

Ref: 54-OR11065

Cilostazol USP Related Compound A

CAS: 54197-66-9

Formula: C₉H₉NO₂

Molecular weight: 163.18

Ref: 4Z-C-0713

6-Hydroxy-3,4-dihydro-1H-quinoline-2-one

Controlled Product

CAS: 54197-66-9

Impurity Cilostazol USP Related Compound A
Applications A metabolite of Cilostazole.
References Gitto, R., et al.: J. Med. Chem., 46, 3758 (2003), Xie, Z., et al.: Bioorg. Med. Chem. Lett., 15, 4803 (2005),

Formula: C₉H₉NO₂

Color and Shape: Neat

Molecular weight: 163.17

Ref: TR-H941423

6-Hydroxy-2-oxo-1,2,3,4-tetrahydroquinoline

CAS: 54197-66-9

Formula: C₉H₉NO₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 163.176

Ref: 10-F011766

6-Hydroxy-3,4-dihydro-1H-quinoline-2-one

CAS: 54197-66-9

This is a quinoline derivative that has been shown to have inotropic and cardioprotective effects. It has been shown to increase the duration of action potentials and contractions in isolated heart muscle, as well as to improve the function of the heart by reducing the rate of myocardial oxygen consumption. 6-Hydroxy-3,4-dihydro-1H-quinoline-2-one has been shown to have anti-inflammatory properties and may be useful for treating respiratory diseases such as asthma. This compound is also used as a precursor for some pharmaceutical drugs, including chloroquine, mefloquine, amodiaquine, and primaquine. The compound is metabolized into conjugates that are recycled back into the body or excreted in human urine; this process is regulated by the balance between conjugation reactions and hydrolysis reactions.

Formula: C₉H₉NO₂

Purity: Min. 95%

Molecular weight: 163.17 g/mol

Ref: 3D-FH24220

Cilostazol USP Related Compound A

CAS: 54197-66-9

Formula: C₉H₉NO₂

Molecular weight: 163.18

Ref: ST-EA-CP-C6001