CAS 5427-99-6

N-(2-Nitrophenyl)glycine

Description:

N-(2-Nitrophenyl)glycine, with the CAS number 5427-99-6, is an organic compound characterized by the presence of both an amino group and a carboxylic acid group, making it an amino acid derivative. It features a nitrophenyl group, which contributes to its distinct chemical properties, including potential reactivity and solubility characteristics. This compound typically appears as a crystalline solid and is soluble in polar solvents due to the presence of the amino and carboxylic acid functional groups. The nitro group on the phenyl ring can influence the compound's electronic properties, making it a subject of interest in various chemical reactions and applications, including studies in medicinal chemistry and as a potential intermediate in organic synthesis. Additionally, its structural features may impart specific biological activities, making it relevant in pharmacological research. Safety data should be consulted, as nitro compounds can exhibit toxicity and environmental concerns.

Formula: C₈H₈N₂O₄

InChI: InChI=1S/C8H8N2O4/c11-8(12)5-9-6-3-1-2-4-7(6)10(13)14/h1-4,9H,5H2,(H,11,12)

InChI key: InChIKey=LGBCEZSPCHBRFQ-UHFFFAOYSA-N

SMILES: N(CC(O)=O)C1=C(N(=O)=O)C=CC=C1

Synonyms:

• 2-[(2-Nitrophenyl)amino]acetic acid
• Glycine, N-(o-nitrophenyl)-
• NSC 12787
• [(2-Nitrophenyl)Amino]Acetic Acid
• glycine, N-(2-nitrophenyl)-
• N-(2-Nitrophenyl)glycine
• N-(2-Nitrophenyl)glycine

2-[(2-Nitrophenyl)amino]acetic acid

CAS: 5427-99-6

Formula: C₈H₈N₂O₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 196.1601

Ref: IN-DA00E0WL

2-((2-Nitrophenyl)amino)acetic acid

CAS: 5427-99-6

2-((2-Nitrophenyl)amino)acetic acid

Purity: 95%

Molecular weight: 196.16g/mol

Ref: 54-OR1052216

2-[(2-nitrophenyl)amino]acetic acid

CAS: 5427-99-6

Purity: 95%

Molecular weight: 196.1620026

Ref: 10-F665346

2-[(2-Nitrophenyl)amino]acetic acid

CAS: 5427-99-6

2-[(2-Nitrophenyl)amino]acetic acid (2NPA) is a selective antagonist with high affinity for the acetylcholine receptor. It has been shown to inhibit ionic currents in Xenopus oocytes expressing α-subunits of the nicotinic acetylcholine receptor. The compound binds to the site on the receptor that is normally occupied by acetylcholine and prevents it from binding to its normal binding site, thereby inhibiting functional activity. 2NPA was found to be a potent inhibitor of acetylcholine release in rat brain synaptosomes and inhibited acetylcholinesterase activity. 2NPA also inhibits cholinergic neurotransmission in the hippocampus, which may be due to its ability to block nicotinic receptors.

Formula: C₈H₈N₂O₄

Purity: Min. 95%

Molecular weight: 196.16 g/mol

Ref: 3D-FAA42799