CAS 54340-58-8

Meptazinol

Description:

Meptazinol is a synthetic compound classified as a non-opioid analgesic and a muscle relaxant. It is primarily used for its analgesic properties in the management of pain, particularly in surgical settings. The substance acts as a central nervous system depressant, providing relief from discomfort without the addictive potential associated with opioids. Meptazinol exhibits a unique mechanism of action, influencing various neurotransmitter systems, including serotonin and norepinephrine pathways. It is typically administered via oral or parenteral routes, depending on the clinical scenario. The compound has a relatively short half-life, necessitating careful dosing to maintain effective analgesia. Side effects may include sedation, dizziness, and gastrointestinal disturbances, which are important considerations in patient management. Due to its specific pharmacological profile, meptazinol is often utilized in combination with other analgesics to enhance pain control while minimizing adverse effects. As with any medication, it is essential to consider contraindications and potential interactions with other drugs when prescribing meptazinol.

Formula: C₁₅H₂₃NO

InChI: InChI=1/C15H23NO/c1-3-15(10-4-5-11-16(2)12-15)13-6-8-14(17)9-7-13/h6-9,17H,3-5,10-12H2,1-2H3

InChI key: InChIKey=JLICHNCFTLFZJN-UHFFFAOYSA-N

SMILES: C(C)C1(CN(C)CCCC1)C2=CC(O)=CC=C2

Synonyms:

• 1-Methyl-3-ethyl-3-(m-hydroxyphenyl)hexahydro-1H-azepine
• 259-109-9
• 3-(3-Ethyl-1-Methylazepan-3-Yl)Phenol
• 3-(3-Ethylhexahydro-1-methyl-1H-azepin-3-yl)phenol
• 4-(3-Ethyl-1-Methyl-Azepan-3-Yl)Phenol
• 54340-58-8
• Meptamizol
• phenol, 3-(3-ethylhexahydro-1-methyl-1H-azepin-3-yl)-
• Meptazinol
• (±)-Meptazinol
• Meptazinol USP/EP/BP
• (+/-)-3-(3-ethyl-1-Methylhexahydro-1H-azepin-3-yl)phenol
• 3-(1-Methyl-3-ethylhexahydro-1H-azepine-3-yl)phenol
• Meptazinol A
• MEPTAZINOL 54340-58-8

Meptazinol-13C-d3

CAS: 54340-58-8

Formula: C₁₄₁₃CH₂₀D₃NO

Color and Shape: Off-White Solid

Molecular weight: 237.37

Ref: 4Z-M-106003

Meptazinol

CAS: 54340-58-8

Formula: C₁₅H₂₃NO

Molecular weight: 233.36

Ref: 4Z-M-106001

Meptazinol-13C,d3 Hydrochloride

Controlled Product

CAS: 2012598-38-6, 54340-58-8, 59263-76-2

Formula: C₁₄CH₂₀D₃NO·HCl

Color and Shape: Neat

Molecular weight: 273.82

Ref: TR-M225082

Meptazinol

CAS: 54340-58-8

Meptazinol is a centrally acting analgesic that inhibits the synthesis of prostaglandins in the central nervous system. It is an ester hydrochloride that has been studied pharmacokinetically and molecularly docked to the cholinergic receptor. Meptazinol has shown to be highly effective in geriatric patients, with a more rapid onset of action than morphine and similar duration of effect. The drug also has a lower incidence of side effects, such as sedation and respiratory depression, which are common with opioid drugs. Meptazinol is chemically stable under acidic conditions, but decomposes at higher pH levels due to its amine group. Biological properties have been determined using the LC-MS/MS method on rat brain tissue samples, showing that meptazinol binds to receptors for opioids with high affinity and selectivity.

Formula: C₁₅H₂₃NO

Purity: Min. 95%

Molecular weight: 233.35 g/mol

Ref: 3D-ECA34058