CAS 54350-48-0
:Etretinate
Description:
Etretinate is a synthetic retinoid, primarily used in dermatology for the treatment of severe skin disorders, particularly psoriasis. It is characterized by its ability to modulate cellular differentiation and proliferation, making it effective in managing hyperproliferative skin conditions. Chemically, etretinate is a derivative of vitamin A and exhibits a structure that allows it to interact with retinoic acid receptors, influencing gene expression related to skin cell growth and differentiation. The substance is lipophilic, which aids in its absorption and efficacy when applied topically. However, etretinate is known for its long half-life and potential for teratogenic effects, leading to strict regulations regarding its use, especially in women of childbearing age. Due to its side effects and the availability of newer retinoids, etretinate has largely been replaced in clinical practice by other treatments. It is important to handle etretinate with caution, considering its pharmacological properties and safety profile.
Formula:C23H30O3
InChI:InChI=1S/C23H30O3/c1-8-26-23(24)14-17(3)11-9-10-16(2)12-13-21-18(4)15-22(25-7)20(6)19(21)5/h9-15H,8H2,1-7H3/b11-9+,13-12+,16-10+,17-14+
InChI key:InChIKey=HQMNCQVAMBCHCO-DJRRULDNSA-N
SMILES:C(=C/C(=C/C=C/C(=C/C(OCC)=O)/C)/C)\C1=C(C)C(C)=C(OC)C=C1C
Synonyms:- 2,4,6,8-Nonatetraenoic acid, 9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-, ethyl ester, (2E,4E,6E,8E)-
- 2,4,6,8-Nonatetraenoic acid, 9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-, ethyl ester, (all-E)-
- Ethyl 9-(4-Methoxy-2,3,6-Trimethylphenyl)-3,7-Dimethylnona-2,4,6,8-Tetraenoate
- Ethyl all-trans-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoate
- Ethyl etrinoate
- Ro 10-9359
- Tegison
- Tigason
- Tigasone
- ethyl (2E,4E,6E,8E)-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoate
- ethyl (all-E)-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoate
- Etretinate
- ethyletrinoate
- ro10-9359
- tetraenoate
- (2E,4E,6E,8E)-9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoic acid ethyl
- (all-E)-9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoic Acid Ethyl Ester
- TRIMETHYLMETHOXYPHENYLETHYLRETINOATE
- 2,4,6,8-nonanetetraenoicacid,9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl
- 3,7-dimethyl-9-(4-methoxy-2,3,6-trimethylphenyl)-2,4,6,8-nonanetetraenoicaci
- (2E,4E,6E,8E)-9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonanetetraenoic acid ethyl ester
- all-trans-ethylester
- (2E,4E,6E,8E)-9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoic acid ethyl ester
- AcitretinEthylEster(ForAcitretin)
- ethylall-trans-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nona
- See more synonyms
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Found 13 products.
Acitretin Related Compound B (ethyl (all-E)-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoate)
CAS:Carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides etc not elsewhere specified or includedFormula:C23H30O3Color and Shape:Yellow PowderMolecular weight:354.21949Acitretin EP Impurity B (Etretinate, Acitretin USP Related Compound B)
CAS:Formula:C23H30O3Molecular weight:354.49Etretinate
CAS:Formula:C23H30O3Purity:>98.0%(HPLC)Color and Shape:White to Yellow to Green powder to crystalMolecular weight:354.49Etretinate
CAS:<p>Etretinate (Ro 10-9359), an oral retinoid, treats psoriasis by promoting cell differentiation and reducing cell growth and inflammation.</p>Formula:C23H30O3Purity:97.89%Color and Shape:Crystals Crystalline SolidMolecular weight:354.48Etretinate
CAS:Controlled Product<p>Used to treat psoriasis; teratogenic</p>Formula:C23H30O3Purity:Min. 98 Area-%Color and Shape:White Yellow PowderMolecular weight:354.21949
