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CAS 543906-09-8

:

Mavoglurant

Description:
Mavoglurant, with the CAS number 543906-09-8, is a selective antagonist of the metabotropic glutamate receptor subtype 5 (mGluR5). It is primarily investigated for its potential therapeutic applications in treating neurological disorders, particularly in conditions such as fragile X syndrome and Parkinson's disease. Mavoglurant is characterized by its ability to modulate glutamatergic signaling, which plays a crucial role in synaptic plasticity and cognitive functions. The compound is typically administered in oral form and has been studied for its effects on behavioral and cognitive outcomes in clinical trials. Its chemical structure includes a specific arrangement of functional groups that contribute to its receptor-binding properties. Mavoglurant's pharmacokinetics, including absorption, distribution, metabolism, and excretion, are essential for understanding its efficacy and safety profile. As research continues, mavoglurant's role in modulating neuropsychiatric conditions remains a significant area of interest in pharmacology and neuroscience.
Formula:C19H23NO3
InChI:InChI=1S/C19H23NO3/c1-14-5-3-6-15(13-14)8-11-19(22)10-4-7-17-16(19)9-12-20(17)18(21)23-2/h3,5-6,13,16-17,22H,4,7,9-10,12H2,1-2H3/t16-,17-,19-/m1/s1
InChI key:InChIKey=ZFPZEYHRWGMJCV-ZHALLVOQSA-N
SMILES:C(#CC1=CC(C)=CC=C1)[C@@]2(O)[C@]3([C@](N(C(OC)=O)CC3)(CCC2)[H])[H]
Synonyms:
  • Mavoglurant
  • 1H-Indole-1-carboxylic acid, octahydro-4-hydroxy-4-[2-(3-methylphenyl)ethynyl]-, methyl ester, (3aR,4S,7aR)-
  • AFQ 056
  • 1H-Indole-1-carboxylic acid, octahydro-4-hydroxy-4-[(3-methylphenyl)ethynyl]-, methyl ester, (3aR,4S,7aR)-
  • (3aR,4S,7aR)-Methyl 4-hydroxy-4-(2-M-tolylethynyl)-octahydroindole-1-carboxylate
  • GT0I9SV4F6
  • UNII-GT0I9SV4F6
  • Mavoglurant, AFQ056
  • UNII-GT0I9SV4F6; AFQ056; MAVOGLURANT; SURECN989279; GT0I9SV4F6; CHEMBL3087515; AFQ 056; AFQ-056
  • SureCN989279
  • See more synonyms
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Found 6 products.