CAS 544-31-0: Palmitoylethanolamide
Description:Palmitoylethanolamide (PEA) is a naturally occurring fatty acid amide, specifically an N-acyl ethanolamine, that is derived from palmitic acid. It is characterized by its role as an endogenous lipid mediator, primarily involved in modulating pain and inflammation. PEA exhibits anti-inflammatory, analgesic, and neuroprotective properties, making it a subject of interest in various therapeutic applications. It is soluble in lipids and has low solubility in water, which influences its bioavailability and pharmacokinetics. PEA interacts with the endocannabinoid system, particularly by influencing the activity of cannabinoid receptors and other receptors such as TRPV1, contributing to its effects on pain perception and inflammation. Additionally, it is considered safe for use, with a favorable side effect profile, and is often explored in dietary supplements and alternative medicine for conditions like chronic pain and neuropathic disorders. Its CAS number, 544-31-0, is used for identification in chemical databases and regulatory contexts.
Formula:C18H37NO2
InChI:InChI=1S/C18H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)19-16-17-20/h20H,2-17H2,1H3,(H,19,21)
InChI key:InChIKey=HXYVTAGFYLMHSO-UHFFFAOYSA-N
SMILES:O=C(NCCO)CCCCCCCCCCCCCCC
- Synonyms:
- (Hydroxyethyl)palmitamide
- 2-(Palmitoylamino)ethanol
- 2-Palmitamidoethanol
- Am 3112
- Hexadecanamide, N-(2-hydroxyethyl)-
- Impulsin
- Loramine P 256
- Mackpeart DR 14V
- N-(2-Hydroxyethyl)hexadecanamide
- N-(2-Hydroxyethyl)palmitamide
- See more synonyms
- N-Hexadecanoylethanolamine
- N-Palmitoylethanolamide
- N-Palmitoylethanolamine
- NSC 23320
- PEA-um
- Palmitic acid ethanolamide
- Palmitic acid monoethanolamide
- Palmitic monoethanolamide
- Palmitoylethanolamide
- Palmidrol
