CAS 54419-31-7
:Fenirofibrate
Description:
Fenofibrate is a pharmaceutical compound primarily used as a lipid-regulating agent to manage dyslipidemia and reduce the risk of cardiovascular disease. It belongs to the class of fibrates, which are derivatives of fibric acid. The chemical formula of fenofibrate is C20H21ClO4, and it features a phenolic structure with a chlorinated aromatic ring, contributing to its lipophilic properties. Fenofibrate acts by activating peroxisome proliferator-activated receptor alpha (PPARα), which enhances the oxidation of fatty acids and decreases triglyceride levels while increasing high-density lipoprotein (HDL) cholesterol. It is typically administered in oral form and is well-absorbed in the gastrointestinal tract. The substance is characterized by its moderate solubility in water and higher solubility in organic solvents, which influences its bioavailability. Common side effects may include gastrointestinal disturbances, and it is contraindicated in patients with severe renal impairment or hypersensitivity to fenofibrate or any of its components. Overall, fenofibrate plays a significant role in lipid management and cardiovascular health.
Formula:C17H17ClO4
InChI:InChI=1/C17H17ClO4/c1-17(2,16(20)21)22-14-9-5-12(6-10-14)15(19)11-3-7-13(18)8-4-11/h3-10,15,19H,1-2H3,(H,20,21)
SMILES:CC(C)(C(=O)O)Oc1ccc(cc1)C(c1ccc(cc1)Cl)O
Synonyms:- Fenirofibrate [INN]
- Lf 2151
- (+-)-2-((alpha-(p-Chlorophenyl)-alpha-hydroxy-p-tolyl)oxy)-2-methylpropionic acid
- Fenirofibrato
- Fenirofibrato [Spanish]
- Fenirofibratum
- Fenirofibratum [Latin]
- Unii-2Vg7825Gp4
- 2-{4-[(4-Chlorophenyl)(Hydroxy)Methyl]Phenoxy}-2-Methylpropanoic Acid
- LF 433-d6
- Fenirofibrate-d6
- SGD-230-74
- 2-[4-(4-Chlorobenzyl)phenoxy]-2-methylpropionic acid
- 2-[4-[(4-Chlorophenyl)hydroxymethyl]phenoxy]-2-methyl-propanoic Acid-d6
- Fenirofibrate
- LF 433
- LF 43
- FENOFIBRIC ACID, HYDROXYMETHYL
- Hydroxymethyl Fenofibric Acid
- Hydroxymethyl Fenofibric Acid-d6
- See more synonyms
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Found 3 products.
Fenofibric acid, hydroxymethyl
CAS:Formula:C17H17ClO4Purity:97%Color and Shape:SolidMolecular weight:320.7675Fenirofibrate
CAS:Fenirofibrate is a metabolite of Fenofibrate.Formula:C17H17ClO4Color and Shape:SolidMolecular weight:320.77Fenirofibrate
CAS:Fenirofibrate is a drug that belongs to the group of drugs called fibrates. It is used to treat metabolic disorders, such as high cholesterol and triglycerides. Fenirofibrate inhibits the activity of human liver cells by inhibiting fatty acid synthesis and oxidation. It also has shown antithrombotic effects in humans. The mechanism of action of fenofibrate may be due to its ability to increase the redox potential in urine samples, which leads to hemolytic activity. The drug has been shown to stimulate growth factor production in human erythrocytes and myotubes. Fenofibrate has been shown to inhibit the activity of lipase enzymes present in the livers of rats and humans, which may contribute to its lipid-lowering properties.Formula:C17H17ClO4Purity:Min. 95 Area-%Color and Shape:PowderMolecular weight:320.77 g/mol



