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CAS 54419-31-7

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Fenirofibrate

Description:
Fenofibrate is a pharmaceutical compound primarily used as a lipid-regulating agent to manage dyslipidemia and reduce the risk of cardiovascular disease. It belongs to the class of fibrates, which are derivatives of fibric acid. The chemical formula of fenofibrate is C20H21ClO4, and it features a phenolic structure with a chlorinated aromatic ring, contributing to its lipophilic properties. Fenofibrate acts by activating peroxisome proliferator-activated receptor alpha (PPARα), which enhances the oxidation of fatty acids and decreases triglyceride levels while increasing high-density lipoprotein (HDL) cholesterol. It is typically administered in oral form and is well-absorbed in the gastrointestinal tract. The substance is characterized by its moderate solubility in water and higher solubility in organic solvents, which influences its bioavailability. Common side effects may include gastrointestinal disturbances, and it is contraindicated in patients with severe renal impairment or hypersensitivity to fenofibrate or any of its components. Overall, fenofibrate plays a significant role in lipid management and cardiovascular health.
Formula:C17H17ClO4
InChI:InChI=1/C17H17ClO4/c1-17(2,16(20)21)22-14-9-5-12(6-10-14)15(19)11-3-7-13(18)8-4-11/h3-10,15,19H,1-2H3,(H,20,21)
SMILES:CC(C)(C(=O)O)Oc1ccc(cc1)C(c1ccc(cc1)Cl)O
Synonyms:
  • Fenirofibrate [INN]
  • Lf 2151
  • (+-)-2-((alpha-(p-Chlorophenyl)-alpha-hydroxy-p-tolyl)oxy)-2-methylpropionic acid
  • Fenirofibrato
  • Fenirofibrato [Spanish]
  • Fenirofibratum
  • Fenirofibratum [Latin]
  • Unii-2Vg7825Gp4
  • 2-{4-[(4-Chlorophenyl)(Hydroxy)Methyl]Phenoxy}-2-Methylpropanoic Acid
  • LF 433-d6
  • See more synonyms
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Found 3 products.
  • Fenofibric acid, hydroxymethyl

    CAS:
    Formula:C17H17ClO4
    Purity:97%
    Color and Shape:Solid
    Molecular weight:320.7675

    Ref: IN-DA00D9TE

    5mg
    509.00€
    10mg
    513.00€
    25mg
    To inquire
    50mg
    To inquire
    100mg
    To inquire
  • Fenirofibrate

    CAS:
    Fenirofibrate is a metabolite of Fenofibrate.
    Formula:C17H17ClO4
    Color and Shape:Solid
    Molecular weight:320.77

    Ref: TM-T31771

    5mg
    238.00€
  • Fenirofibrate

    CAS:
    Fenirofibrate is a drug that belongs to the group of drugs called fibrates. It is used to treat metabolic disorders, such as high cholesterol and triglycerides. Fenirofibrate inhibits the activity of human liver cells by inhibiting fatty acid synthesis and oxidation. It also has shown antithrombotic effects in humans. The mechanism of action of fenofibrate may be due to its ability to increase the redox potential in urine samples, which leads to hemolytic activity. The drug has been shown to stimulate growth factor production in human erythrocytes and myotubes. Fenofibrate has been shown to inhibit the activity of lipase enzymes present in the livers of rats and humans, which may contribute to its lipid-lowering properties.
    Formula:C17H17ClO4
    Purity:Min. 95 Area-%
    Color and Shape:Powder
    Molecular weight:320.77 g/mol

    Ref: 3D-FF23251

    1mg
    148.00€
    2mg
    193.00€