3'-Adenylic acid, also known as cyclic adenosine monophosphate (cAMP), is a cyclic nucleotide that plays a crucial role in cellular signaling processes. It is characterized by its cyclic structure, which consists of a ribose sugar, a phosphate group, and adenine as the nitrogenous base. The unique 3' to 5' phosphodiester bond in cAMP allows it to function as a secondary messenger in various biological pathways, particularly in the regulation of metabolism, gene expression, and cell signaling. cAMP is synthesized from ATP by the enzyme adenylate cyclase and is degraded by phosphodiesterases. Its levels are tightly regulated within the cell, as fluctuations can significantly impact physiological responses. This compound is involved in numerous signaling cascades, including those triggered by hormones like adrenaline and glucagon, making it vital for processes such as glycogen breakdown and lipolysis. The CAS number 54447-85-7 identifies this specific cyclic nucleotide, which is widely studied for its role in biochemistry and pharmacology.

3'-Adenylic acid, adenylyl-(3'→5')-adenylyl-(3'→5')-, cyclic nucleotide (9CI)

54447-85-7: 3'-Adenylic acid, also known as cyclic adenosine monophosphate (cAMP), is a cyclic nucleotide that plays a crucial role in cellular signaling processes. It is characterized by its cyclic structure, which consists of a ribose sugar, a phosphate group, and adenine as the nitrogenous base. The unique 3' to 5' phosphodiester bond in cAMP allows it to function as a secondary messenger in various biological pathways, particularly in the regulation of metabolism, gene expression, and cell signaling. cAMP is synthesized from ATP by the enzyme adenylate cyclase and is degraded by phosphodiesterases. Its levels are tightly regulated within the cell, as fluctuations can significantly impact physiological responses. This compound is involved in numerous signaling cascades, including those triggered by hormones like adrenaline and glucagon, making it vital for processes such as glycogen breakdown and lipolysis. The CAS number 54447-85-7 identifies this specific cyclic nucleotide, which is widely studied for its role in biochemistry and pharmacology.

<p>Cyclic tri-AMP is a key element of the cyclic oligonucleotide-based anti-phage signaling system (CBASS), functioning as a second messenger in the immune defense against viral infections. It activates DNA endonuclease NucC through binding, leading to cell death and demonstrating antiviral properties.</p>

CAS 54447-85-7

3'-Adenylic acid, adenylyl-(3'→5')-adenylyl-(3'→5')-, cyclic nucleotide (9CI)

Cyclic tri-AMP

Ref: TM-T88085