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CAS 54455-37-7

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N-Chloromethyl-4-nitrophthalimide [for HPLC Labeling]

Description:
N-Chloromethyl-4-nitrophthalimide, with the CAS number 54455-37-7, is a chemical compound characterized by its unique structure, which includes a nitrophthalimide moiety and a chloromethyl group. This compound is typically used in high-performance liquid chromatography (HPLC) for labeling purposes, particularly in the analysis of biomolecules. It exhibits a yellow crystalline appearance and is soluble in organic solvents, making it suitable for various analytical applications. The presence of the nitro group contributes to its reactivity, allowing it to participate in nucleophilic substitution reactions, which is essential for its labeling function. Additionally, the chloromethyl group enhances its electrophilic character, facilitating interactions with nucleophiles such as amines or thiols. Safety considerations should be taken into account when handling this compound, as it may pose health risks due to its reactive nature. Overall, N-Chloromethyl-4-nitrophthalimide is a valuable reagent in analytical chemistry, particularly in the context of biomolecular studies.
Formula:C9H5ClN2O4
Synonyms:
  • 1H-Isoindole-1,3(2H)-dione, 2-(chloromethyl)-5-nitro-
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