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CAS 5446-77-5

:

ethyl 4-sulfamoylbenzoate

Description:
Ethyl 4-sulfamoylbenzoate, with the CAS number 5446-77-5, is an organic compound characterized by its sulfonamide functional group and an ester linkage. It features a benzoate structure where a sulfonamide group is attached to the para position of the aromatic ring. This compound is typically a white to off-white solid and is soluble in polar organic solvents. Ethyl 4-sulfamoylbenzoate exhibits properties that make it useful in medicinal chemistry, particularly in the development of pharmaceuticals due to its potential antibacterial and anti-inflammatory activities. The presence of the sulfonamide group contributes to its biological activity, while the ethyl ester enhances its solubility and bioavailability. As with many sulfonamides, it may also exhibit some degree of toxicity and should be handled with care in laboratory settings. Its synthesis often involves the reaction of 4-aminobenzoic acid derivatives with ethyl chloroformate and a sulfonamide reagent, highlighting its relevance in organic synthesis and drug development.
Formula:C9H11NO4S
InChI:InChI=1/C9H11NO4S/c1-2-14-9(11)7-3-5-8(6-4-7)15(10,12)13/h3-6H,2H2,1H3,(H2,10,12,13)
SMILES:CCOC(=O)c1ccc(cc1)S(=O)(=O)N
Synonyms:
  • Benzoic Acid, 4-(Aminosulfonyl)-, Ethyl Ester
  • Ethyl 4-sulfamoylbenzoate
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