CAS 544684-93-7

4-[4-(Methylsulfonyl)phenyl]-3-(phenyl-d5)-

Description:

The chemical substance known as 4-[4-(Methylsulfonyl)phenyl]-3-(phenyl-d5)-, with the CAS number 544684-93-7, is a compound that features a complex aromatic structure. It contains a methylsulfonyl group, which is a sulfonyl functional group attached to a methyl group, indicating potential polar characteristics that can influence its solubility and reactivity. The presence of deuterated phenyl groups (phenyl-d5) suggests that this compound may be used in studies requiring isotopic labeling, such as NMR spectroscopy, to trace molecular interactions or dynamics. The overall structure indicates that it may exhibit significant hydrophobic characteristics due to the aromatic rings, which could affect its biological activity and interactions with other molecules. Additionally, the methylsulfonyl group may impart unique chemical reactivity, making it of interest in medicinal chemistry or materials science. As with many organic compounds, its stability, reactivity, and potential applications would depend on the specific conditions under which it is used.

Formula: C₁₇H₁₄O₄S

Synonyms:

• Vioxx-d5 (Major)
• 4-[4-(Methylsulfonyl)phenyl]-3-(phenyl-d5)-

Rofecoxib-d5

CAS: 544684-93-7

Formula: C₁₇H₉D₅O₄S

Color and Shape: White To Off-White Solid

Molecular weight: 319.39

Ref: 4Z-R-752

Vioxx-d5 (Major)

Controlled Product

CAS: 544684-93-7

Applications A selective labelled cyclooxygenase-2 (COX-2) inhibitor. Use as an anti-inflammatory, analgesic.
References Catalla-Lawson, F., et al.: J. Pharmacol. Exp. Ther., 289, 735 (1999), Ehrich, E.W., et al.: Clin. Pharmacol. Ther., 65, 336 (1999), Langman, M.J., et al.: J. Am. Med. Assoc., 282, 1929 (1999),

Formula: C₁₇₂H₅H₉O₄S

Color and Shape: Neat

Molecular weight: 319.387

Ref: TR-V670002

Vioxx-d5 (Major)

Controlled Product

CAS: 544684-93-7

Formula: C₁₇₂H₅H₉O₄S

Ref: TR-TRC-V670002

Vioxx-d5 (major)

Controlled Product

CAS: 544684-93-7

Rofecoxib is a non-steroidal anti-inflammatory drug (NSAID) that belongs to the coxib class of drugs. It is used for the relief of pain, inflammation, and stiffness associated with osteoarthritis and rheumatoid arthritis. Rofecoxib inhibits cyclooxygenase-2 (COX-2), which is responsible for making prostaglandins. COX-2 inhibitors are also used as an analgesic in cancer patients and those with chronic inflammatory diseases. Celecoxib is another NSAID that belongs to the coxib class of drugs. It has been shown to be effective in treating pain and inflammation in osteoarthritis and rheumatoid arthritis patients. These drugs may have long-term toxicity effects, such as increased risk of cancer or other diseases, but more research needs to be done before these conclusions can be made.

Formula: C₁₇H₁₄O₄S

Purity: Min. 95%

Molecular weight: 314.4 g/mol

Ref: 3D-UWA68493