CAS 545-55-1

Triethylenephosphoramide

Description:

Triethylenephosphoramide (TEPA) is an organophosphorus compound characterized by its use as a solvent and reagent in various chemical applications. It is a colorless to pale yellow liquid with a relatively high boiling point and low volatility, making it suitable for high-temperature reactions. TEPA is known for its ability to act as a polar aprotic solvent, which facilitates nucleophilic reactions by stabilizing ions in solution. The compound exhibits moderate toxicity and should be handled with care, as it can cause irritation upon contact with skin or mucous membranes. Additionally, TEPA is hygroscopic, meaning it can absorb moisture from the air, which may affect its reactivity and storage conditions. Its chemical structure features a phosphorus atom bonded to nitrogen atoms, contributing to its unique properties and reactivity. Due to these characteristics, triethylenephosphoramide finds applications in organic synthesis, particularly in the preparation of phosphoramides and as a reagent in various chemical transformations.

Formula: C₆H₁₂N₃OP

InChI: InChI=1S/C6H12N3OP/c10-11(7-1-2-7,8-3-4-8)9-5-6-9/h1-6H2

InChI key: InChIKey=FYAMXEPQQLNQDM-UHFFFAOYSA-N

SMILES: P(=O)(N1CC1)(N2CC2)N3CC3

Synonyms:

• 1,1',1''-Phosphinylidynetrisaziridine
• 1,1',1''-Phosphoryltriaziridine
• 1,1′,1′′-Phosphinylidynetris[aziridine]
• A 6366
• APO
• Ai3-24915
• Aphoxide
• Aziridine, 1,1',1"-phosphinylidynetris-
• Aziridine, 1,1′,1′′-phosphinylidynetris-
• Brn 0145971
• Cbc 906288
• Ent 24915
• Hexamethylphosphoric triamide tris(1-aziridinyl)phosphine oxide
• Hsdb 1011
• Imperon fixer T
• N,N',N -triethylenephosphoramide
• N,N',N''-Tri-1,2-ethanediylphosphoric triamide
• N,N',N''-Triethylenephosphoric triamide
• Nsc 9717
• Phosphine oxide, tris(1-aziridinyl)-
• Phosphoramide, N,N',N -triethylene-
• Phosphoric acid triethylene imide
• Phosphoric triamide, N,N',N -triethylene-
• Phosphoric triamide, N,N',N''-tri-1,2-ethanediyl-
• Sk-3818
• TEF
• TEPA (pesticide)
• Tapo
• Tepa
• Tri-1-aziridinylphosphine oxide
• Triaethylenphosphorsaeureamid
• Triaethylenphosphorsaeureamid [German]
• Triaziridinophosphine oxide
• Triaziridinylphosphine oxide
• Triethylene phophoramide
• Triethylene phosphoramide
• Triethylenephosphoramide
• Triethylenephosphoric triamide
• Triethylenephosphorotriamide
• Triethylenepyrophosphoramide
• Triethylenfosforamid
• Triethylenfosforamid [Czech]
• Tris(1-aziridine)phosphine oxide
• Tris(1-aziridinyl)phosphine oxide
• Tris(1-aziridinyl)phosphine oxide, solution
• Tris(1-aziridinyl)phosphine oxide, solution [UN2501] [Poison]
• Tris(N-ethylene)phosphorotriamidate
• Tris(aziridinyl)phosphine oxide
• Tris-(1-aziridinyl)-phosphineoxide
• Tris-(1-aziridinyl)fosfinoxid
• Tris-(1-aziridinyl)fosfinoxid [Czech]
• Un2501
• Tri(aziridin-1-yl)phosphine oxide

N,N',N''-triethylenephosphoramide

CAS: 545-55-1

Formula: C₆H₁₂N₃OP

Molecular weight: 173.16

Ref: 4Z-T-184020

Triethylenephosphoramide

CAS: 545-55-1

Stability Hygroscopic, Moisture Sensitive
Applications Used as insect chemosterilant; in dyeing. Antineoplastic.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Gaines, et al.: Toxicol. Appl. Pharmacol., 14, 515 (1969), Huitema, A., et al.: Br. J. Clin. Pharmacol., 51, 61 (2001), Jinno, H., et al.: Drug Metab. Dispos., 31, 398 (2003),

Formula: C₆H₁₂N₃OP

Color and Shape: Yellowish Solid With A Low Melting Point

Molecular weight: 173.15

Ref: TR-T776600

Triethylenephosphoramide

CAS: 545-55-1

Triethylenephosphoramide (TEP) is a model system for studying the reaction mechanism of the enzyme phosphotriesterase. TEP has been used in reactions with water vapor, which causes the release of hydrogen chloride. The reaction solution is analyzed by mass spectrometry to determine the reaction products. TEP has also been shown to inhibit nitrite ion-dependent enzymes such as nitrate reductase and aminopeptidase N. TEP reacts with fluorescence probes that have been modified with response elements to detect the binding of these probes to DNA and RNA. This helps researchers identify the location of TEP in proteins and nucleic acids.

Formula: C₆H₁₂N₃OP

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 173.15 g/mol

Ref: 3D-FT28432

Triethylenephosphoramide

CAS: 545-55-1

Formula: C₆H₁₂N₃OP

Molecular weight: 173.16

Ref: ST-EA-CP-T149005