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CAS 54504-70-0

:

Theofibrate

Description:
Theofibrate, with the CAS number 54504-70-0, is a chemical compound that belongs to the class of fibrates, which are primarily used as lipid-lowering agents. It is characterized by its ability to activate peroxisome proliferator-activated receptors (PPARs), which play a crucial role in the regulation of fatty acid metabolism and glucose homeostasis. Theofibrate is typically utilized in the management of dyslipidemia, particularly to reduce triglyceride levels and increase high-density lipoprotein (HDL) cholesterol. The compound is often administered in its ester form, which enhances its bioavailability. In terms of its chemical structure, Theofibrate features a phenoxyacetic acid moiety, contributing to its pharmacological activity. It is generally well-tolerated, but like other fibrates, it may have side effects, including gastrointestinal disturbances and potential interactions with other medications. Overall, Theofibrate represents a significant therapeutic option in the management of lipid disorders, particularly in patients who are at risk for cardiovascular diseases.
Formula:C19H21ClN4O5
InChI:InChI=1S/C19H21ClN4O5/c1-19(2,29-13-7-5-12(20)6-8-13)17(26)28-10-9-24-11-21-15-14(24)16(25)23(4)18(27)22(15)3/h5-8,11H,9-10H2,1-4H3
InChI key:InChIKey=KYAKGJDISSNVPZ-UHFFFAOYSA-N
SMILES:C(COC(C(OC1=CC=C(Cl)C=C1)(C)C)=O)N2C3=C(N=C2)N(C)C(=O)N(C)C3=O
Synonyms:
  • 1-(7-Theophyllinyl)-2-ethyl (2-(p-chlorophenoxy)isobutyrate)
  • 1-(Theophyllin-7-yl)-aethyl-2 2-(p-chlorphenoxy)-2-methylpropionat
  • 1-(Theophyllin-7-yl)-aethyl-2 2-(p-chlorphenoxy)-2-methylpropionat [German]
  • 1-(Theophyllin-7-yl)-ethyl-2 2-(p-chlorophenoxy)-2-methylpropionate
  • 2-(1,3-Dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-7-yl)ethyl 2-(4-chlorophenoxy)-2-methylpropanoate
  • 2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)ethyl 2-(4-chlorophenoxy)-2-methylpropanoate
  • 2-(p-Chlorophenoxy)-2-methylpropionic acid, ester with 7-(2-hydroxyethyl)theophylline
  • Brn 1233286
  • Clofibrate d'etofylline
  • Clofibrate d'etofylline [INN-French]
  • See more synonyms
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Found 2 products.
  • Etofylline clofibrate
    Targetmol
    + Info

    Etofylline clofibrate

    CAS:
    <p>Etofylline clofibrate has a hypolipidemic and antithrombotic effect and it also has an agonistic interaction with intimal PGI2.</p>
    Formula:C19H21ClN4O5
    Color and Shape:Solid
    Molecular weight:420.85

    Ref: TM-T15256

  • Etofylline clofibrate
    Biosynth
    + Info

    Etofylline clofibrate

    Controlled Product
    CAS:
    <p>Etofylline is a metabolite of clofibrate that has been used in the treatment of symptoms related to hyperlipidemia. It is an analog of etyfylline, which is a bronchodilator and anti-inflammatory drug. Etofylline inhibits the activity of hepatic lipase, an enzyme that causes the breakdown of triglycerides into free fatty acids and glycerol. This inhibition may be responsible for the reduction in serum cholesterol levels. The effects of etofylline on human serum have been tested using a double-blind cross-over study with healthy volunteers. Results showed that it inhibited the activity of dpp-iv, an enzyme that degrades proteins involved in blood clotting and coagulation. Etofylline also inhibits the activity of other enzymes such as phosphodiesterase, which increases cAMP levels, and acetylcholinesterase, which breaks down acetylcholine.</p>
    Formula:C19H21ClN4O5
    Purity:Min. 95%
    Molecular weight:420.85 g/mol

    Ref: 3D-ECA50470

    250mg
    957.00€
    500mg
    1,254.00€