CAS 54522-52-0

Methylprotodioscin

Description:

Methylprotodioscin is a naturally occurring steroidal saponin, primarily found in various plant species, particularly in the genus Dioscorea. It is characterized by its complex molecular structure, which includes a steroid backbone and sugar moieties, contributing to its biological activity. This compound is known for its potential pharmacological properties, including anti-inflammatory, immunomodulatory, and anticancer effects. Methylprotodioscin has garnered interest in traditional medicine and modern pharmacology due to its ability to influence various biological pathways. Its solubility and stability can vary depending on the solvent and environmental conditions, which can affect its bioavailability and efficacy. As with many saponins, it may exhibit surface-active properties, influencing cell membrane interactions. Research into methylprotodioscin continues to explore its therapeutic potential and mechanisms of action, making it a subject of interest in both natural product chemistry and drug development. However, further studies are necessary to fully elucidate its pharmacokinetics and safety profile.

Formula: C₅₂H₈₆O₂₂

InChI: InChI=1S/C52H86O22/c1-21(20-66-46-40(61)39(60)36(57)31(18-53)70-46)10-15-52(65-7)22(2)33-30(74-52)17-29-27-9-8-25-16-26(11-13-50(25,5)28(27)12-14-51(29,33)6)69-49-45(73-48-42(63)38(59)35(56)24(4)68-48)43(64)44(32(19-54)71-49)72-47-41(62)37(58)34(55)23(3)67-47/h8,21-24,26-49,53-64H,9-20H2,1-7H3/t21-,22+,23+,24+,26+,27-,28+,29+,30+,31-,32-,33+,34+,35+,36-,37-,38-,39+,40-,41-,42-,43+,44-,45-,46-,47+,48+,49-,50+,51+,52-/m1/s1

InChI key: InChIKey=HSSJYSJXBOCKQM-GVTGEURHSA-N

SMILES: C[C@@]12[C@]([C@]3([C@](CC1)([C@]4(C)C(=CC3)C[C@@H](O[C@H]5[C@H](O[C@H]6[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O6)[C@@H](O)[C@H](O[C@H]7[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O7)[C@@H](CO)O5)CC4)[H])[H])(C[C@]8([C@@]2([C@H](C)[C@](CC[C@H](CO[C@@H]9O[C@H](CO)[C@@H](O)[C@H](O)[C@H]9O)C)(OC)O8)[H])[H])[H]

Synonyms:

• (3beta,22R,25R)-26-(beta-D-glucopyranosyloxy)-22-methoxyfurost-5-en-3-yl 6-deoxy-alpha-L-mannopyranosyl-(1->2)-[6-deoxy-alpha-L-mannopyranosyl-(1->4)]-(2xi)-beta-D-arabino-hexopyranoside
• (3β,22α,25R)-26-(β-<span class="text-smallcaps">D</smallcap>-Glucopyranosyloxy)-22-methoxyfurost-5-en-3-yl O-6-deoxy-α-<smallcap>L</smallcap>-mannopyranosyl-(1→2)-O-[6-deoxy-α-<smallcap>L</smallcap>-mannopyranosyl-(1→4)]-β-<smallcap>D</span>-glucopyranoside
• 22-Methoxylprotodioscin
• 22-O-Methylprotodioscin
• 3b,26-Dihydroxy-22a-methoxyfurost-5-ene 3-O-beta-chacotrioside 26-O-beta-D-glucopyranoside
• 3β,26-Dihydroxy-22α-methoxyfurost-5-ene 3-O-β-chacotrioside 26-O-β-<span class="text-smallcaps">D</span>-glucopyranoside
• NSC 698790
• Smilax saponin B
• β-<span class="text-smallcaps">D</smallcap>-Glucopyranoside, (3β,22α,25R)-26-(β-<smallcap>D</smallcap>-glucopyranosyloxy)-22-methoxyfurost-5-en-3-yl O-6-deoxy-α-<smallcap>L</smallcap>-mannopyranosyl-(1→2)-O-[6-deoxy-α-<smallcap>L</span>-mannopyranosyl-(1→4)]-
• (3β,22α,25R)-26-(β-D-Glucopyranosyloxy)-22-methoxyfurost-5-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[6-deoxy-α-L-mannopyranosyl-(1→4)]-β-D-glucopyranoside
• 3β,26-Dihydroxy-22α-methoxyfurost-5-ene 3-O-β-chacotrioside 26-O-β-D-glucopyranoside
• β-D-Glucopyranoside, (3β,22α,25R)-26-(β-D-glucopyranosyloxy)-22-methoxyfurost-5-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[6-deoxy-α-L-mannopyranosyl-(1→4)]-

Methyl protodioscin

CAS: 54522-52-0

Formula: C₅₂H₈₆O₂₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 1063.2260

Ref: IN-DA00DB8Y

Methyl protodioscin

CAS: 54522-52-0

Formula: C₅₂H₈₆O₂₂

Molecular weight: 1063.24

Ref: 7W-GY3135

Methyl protodioscin

CAS: 54522-52-0

Formula: C₅₂H₈₆O₂₂

Purity: 95%~99%

Molecular weight: 1063.24

Ref: BP-BP0939

Methyl protodioscin

CAS: 54522-52-0

Methyl protodioscin boosts HDL, lowers LDL and triglycerides, has anti-cancer effects, and promotes apoptosis via mitochondrial pathways.

Formula: C₅₂H₈₆O₂₂

Purity: 99.308% - 99.73%

Color and Shape: Solid

Molecular weight: 1063.23

Ref: TM-T3771

Methyl protodioscin

CAS: 54522-52-0

Methyl protodioscin is a natural compound that has been shown to have a promising therapeutic effect on autoimmune diseases. Methyl protodioscin is derived from soybean extract and it is known to inhibit the translocation of bacteria across the gut wall, which could be due to its ability to regulate mucin gene expression. In vitro assays show that methyl protodioscin has an effect on mitochondrial membrane potential, which may be related to its anti-inflammatory properties. The effects of methyl protodioscin on mitochondrial functions were studied in C. glabrata, and it was shown that this compound can be used as a therapeutic agent for balloon injury.
Methyl protodioscin also inhibits the growth of Candida albicans and other fungi in vivo, suggesting that this compound might have antifungal activity.

Formula: C₅₂H₈₆O₂₂

Purity: Min. 95%

Molecular weight: 1,063.23 g/mol

Ref: 3D-OM73875

Methylprotodioscin

Controlled Product

CAS: 54522-52-0

Stability Hygroscopic
Applications Methylprotodioscin is a steroidal saponin compound found in a number of plant species. It is known to be the active component of the herbal aphrodisiac plant Tribulus terrestris. It has also shown to produce significant increases in the levels of the hormonal levels in animal studies.
References Gauthaman, K., et al.: Inter. J. Phytother. Phytopharm., 15, 44 (2008); Ganzera, M., et al.: J. Pharmac. Sci., 90(11), 1752 (2001);

Formula: C₅₂H₈₆O₂₂

Color and Shape: Neat

Molecular weight: 1063.23

Ref: TR-M328245