CAS 546-18-9

5β-Cholanic acid

Description:

5β-Cholanic acid, also known as cholanic acid, is a steroidal compound characterized by its structure, which includes a four-ring carbon framework typical of steroids. It is a derivative of cholesterol and is classified as a bile acid precursor. This compound is typically white to off-white in appearance and is soluble in organic solvents but has limited solubility in water. 5β-Cholanic acid plays a significant role in the biosynthesis of bile acids, which are crucial for the digestion and absorption of dietary fats. Its chemical formula is C24H40O2, indicating the presence of a carboxylic acid functional group, which contributes to its acidic properties. The compound is of interest in various fields, including biochemistry and pharmacology, due to its involvement in lipid metabolism and potential therapeutic applications. Additionally, it can serve as a biochemical marker in studies related to cholesterol metabolism and liver function. Safety data should be consulted for handling and usage, as with all chemical substances.

Formula: C₂₄H₄₀O₂

InChI: InChI=1S/C24H40O2/c1-16(7-12-22(25)26)19-10-11-20-18-9-8-17-6-4-5-14-23(17,2)21(18)13-15-24(19,20)3/h16-21H,4-15H2,1-3H3,(H,25,26)/t16-,17+,18+,19-,20+,21+,23+,24-/m1/s1

InChI key: InChIKey=RPKLZQLYODPWTM-LVVAJZGHSA-N

SMILES: C[C@@]12[C@]([C@]3([C@](CC1)([C@]4(C)[C@](CC3)(CCCC4)[H])[H])[H])(CC[C@@]2([C@@H](CCC(O)=O)C)[H])[H]

Synonyms:

• (5β)-Cholan-24-oic acid
• 4-[(5S,10S,13R,17R)-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
• 5-Beta-Cholan-24-Oic Acid
• 5-Beta-Cholanic Acid
• 5β-Cholanic acid
• 5β-Cholanoic acid
• Androstane-17-butanoic acid, γ-methyl-, (5β,17β)-
• Cholan-24-Oic Acid
• Cholan-24-oic acid, (5β)-
• Cholanoic acid
• L 596205-0
• NSC 18161

5β-CHOLANIC ACID

CAS: 546-18-9

Formula: C₂₄H₄₀O₂

Purity: 99%

Color and Shape: Solid

Molecular weight: 360.5732

Ref: IN-DA00DEPI

5β-Cholanic acid

CAS: 546-18-9

5β-Cholanic acid

Purity: ≥98%

Molecular weight: 360.57g/mol

Ref: 54-BUP06626

5β-Cholanic acid

CAS: 546-18-9

Formula: C₂₄H₄₀O₂

Purity: ≥ 95.0%

Color and Shape: White to off-white powder

Molecular weight: 360.57

Ref: 7W-GL5273

5β-Cholanic acid

CAS: 546-18-9

5β-Cholanic acid (5beta-Cholanic acid) is a potent γ-secretase modulator used in Alzheimer's disease research.

Formula: C₂₄H₄₀O₂

Purity: 98.91% - 99.89%

Color and Shape: Soild

Molecular weight: 360.57

Ref: TM-T88859

5-β-Cholanic Acid

CAS: 546-18-9

Formula: C₂₄H₄₀O₂

Molecular weight: 360.58

Ref: 4Z-C-203002

Cholanoic Acid

Controlled Product

CAS: 546-18-9

Formula: C₂₄H₄₀O₂

Color and Shape: Neat

Molecular weight: 360.57

Ref: TR-C431430

5β-Cholanic acid

Controlled Product

CAS: 546-18-9

5beta-Cholanic acid is a fatty acid that is the product of cholesterol metabolism. It has been shown to inhibit tumor growth by binding to ATP-binding cassette transporter and blocking the transport of tumor cells. 5beta-Cholanic acid also inhibits HIV infection by interfering with the virus's ability to bind and enter host cells. 5beta-Cholanic acid may also be used as a treatment for autoimmune diseases such as multiple sclerosis, rheumatoid arthritis, ulcerative colitis and Crohn's disease. This compound has been shown to inhibit mitochondrial membrane potential and induce apoptosis in prostate cancer cells in vitro. The mechanism of action for this compound is not well understood but it may be due to its ability to decrease ATP levels in mitochondria or interfere with the production of bile acids from cholesterol by inhibiting hydroxylation reactions.

Formula: C₂₄H₄₀O₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 360.57 g/mol

Ref: 3D-FC71630